NACC2 and MTA2

Number of citations of the paper that reports this interaction (PMID 22926524)
0

Data Source:
BioGRID (pull down)

		NACC2	MTA2
Gene Name		NACC family member 2, BEN and BTB (POZ) domain containing	metastasis associated 1 family, member 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Chromatin Nucleus NuRD Complex Nuclear Body	Histone Deacetylase Complex Nuclear Chromatin Nucleoplasm Transcription Factor Complex Membrane NuRD Complex Protein Complex
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Binding Transcription Factor Activity RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription Histone Deacetylase Activity Protein Binding Protein Homodimerization Activity Histone Deacetylase Binding	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Binding Transcription Factor Activity RNA Polymerase II Transcription Factor Binding RNA Polymerase II Repressing Transcription Factor Binding Sequence-specific DNA Binding Transcription Factor Activity Histone Deacetylase Activity Protein Binding Zinc Ion Binding Nucleosomal DNA Binding
	Biological Process	Transcription From RNA Polymerase II Promoter Positive Regulation Of Cell Proliferation Negative Regulation Of Cell Proliferation Posttranscriptional Regulation Of Gene Expression Histone Deacetylation Cellular Protein Complex Localization Negative Regulation Of Transcription, DNA-templated Protein Homooligomerization Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle By Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage	Negative Regulation Of Transcription From RNA Polymerase II Promoter DNA Methylation Chromatin Organization Chromatin Assembly Or Disassembly Histone Deacetylation ATP-dependent Chromatin Remodeling Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways			Chromatin modifying enzymes Chromatin organization HDACs deacetylate histones RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase I Transcription RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Clearance
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: EPS8 HDAC2 MTA1 MTA2 MTA3	21 interactors: APPL1 APPL2 BCL11B ESR1 FKBP3 HDAC2 HIST3H3 HNRNPD MBD3 MBD3L2 MED30 NACC2 RBBP4 RBBP7 SATB1 SATB2 SPEN TP53 TSC22D3 UBE3C YY1
Entrez ID		138151	9219
HPRD ID		09831	07233
Ensembl ID		ENSG00000148411	ENSG00000149480
Uniprot IDs		Q96BF6	O94776
PDB IDs
Enriched GO Terms of Interacting Partners?		Chromatin Organization Regulation Of Gene Expression, Epigenetic Chromosome Organization Organelle Organization Histone Deacetylation Protein Deacetylation ATP-dependent Chromatin Remodeling Circadian Regulation Of Gene Expression Positive Regulation Of Protein Autoubiquitination Circadian Rhythm Chromatin Remodeling Regulation Of Protein Autoubiquitination Maintenance Of Chromatin Silencing Actin Polymerization-dependent Cell Motility Locomotory Behavior Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of MHC Class II Biosynthetic Process Exit From Mitosis Fungiform Papilla Formation Negative Regulation Of Cardiac Muscle Cell Proliferation Rhythmic Process Negative Regulation Of Biosynthetic Process Fungiform Papilla Morphogenesis Behavioral Response To Ethanol Locomotor Rhythm Positive Regulation Of Receptor Biosynthetic Process Regulation Of Actin Cytoskeleton Organization Fungiform Papilla Development Regulation Of Sarcomere Organization Eyelid Development In Camera-type Eye Histone Modification Regulation Of Actin Filament-based Process Hair Follicle Placode Formation Positive Regulation Of Oligodendrocyte Differentiation Tongue Morphogenesis Negative Regulation Of Cardiac Muscle Tissue Development Single-organism Behavior Rac Protein Signal Transduction Regulation Of Receptor Biosynthetic Process Circadian Behavior Histone H4 Deacetylation Rhythmic Behavior Regulation Of Cytoskeleton Organization Barbed-end Actin Filament Capping Actin Crosslink Formation Dendritic Cell Migration Regulation Of Transcription, DNA-templated Entrainment Of Circadian Clock By Photoperiod Regulation Of Nucleic Acid-templated Transcription	Negative Regulation Of Gene Expression Chromosome Organization Chromatin Remodeling Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription From RNA Polymerase II Promoter RNA Biosynthetic Process Chromatin Organization Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process RNA Metabolic Process Chromatin Modification Regulation Of Nitrogen Compound Metabolic Process Gene Expression Negative Regulation Of Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Transcription From RNA Polymerase II Promoter ATP-dependent Chromatin Remodeling Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Gene Expression, Epigenetic Nitrogen Compound Metabolic Process Positive Regulation Of Gene Expression Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Regulation Of Metabolic Process Organelle Organization Positive Regulation Of Macromolecule Biosynthetic Process Cell Proliferation Positive Regulation Of Cellular Biosynthetic Process Regulation Of Gene Expression, Epigenetic Commitment Of Neuronal Cell To Specific Neuron Type In Forebrain Rhythmic Process Regulation Of Apoptotic Process Forebrain Neuron Fate Commitment Cellular Metabolic Process Regulation Of Cell Death DNA Metabolic Process Negative Regulation Of Cell Proliferation Chromatin Assembly
Tagcloud ?			ag ag1478 blocking combat combinatorial dosage egfr exerts fasn greatly hsp90 ideal iialpha iressa isotope labeling lc mechanistically oncogenes phosphatidylinositol pi3k pi4kiialpha prdx2 presents proteomic silac strengthened ultimately xenograft
Tagcloud (Difference) ?			ag ag1478 blocking combat combinatorial dosage egfr exerts fasn greatly hsp90 ideal iialpha iressa isotope labeling lc mechanistically oncogenes phosphatidylinositol pi3k pi4kiialpha prdx2 presents proteomic silac strengthened ultimately xenograft
Tagcloud (Intersection) ?