COL6A1 and LGALS3BP

Number of citations of the paper that reports this interaction (PMID 9501082)
21

Data Source:
HPRD (in vivo, in vitro)

		COL6A1	LGALS3BP
Gene Name		collagen, type VI, alpha 1	lectin, galactoside-binding, soluble, 3 binding protein
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Proteinaceous Extracellular Matrix Collagen Type VI Trimer Lysosomal Membrane Endoplasmic Reticulum Lumen Membrane Extracellular Matrix Sarcolemma Protein Complex Extracellular Vesicular Exosome	Proteinaceous Extracellular Matrix Extracellular Space Membrane Extracellular Matrix Extracellular Vesicular Exosome Blood Microparticle
	Molecular Function	Platelet-derived Growth Factor Binding	Scavenger Receptor Activity
	Biological Process	Osteoblast Differentiation Cell Adhesion Axon Guidance Extracellular Matrix Disassembly Extracellular Matrix Organization Collagen Catabolic Process Endodermal Cell Differentiation Protein Heterotrimerization Cellular Response To Amino Acid Stimulus	Receptor-mediated Endocytosis Cellular Defense Response Cell Adhesion Signal Transduction
Pathways		Signaling by PDGF NCAM1 interactions Collagen formation Axon guidance Collagen degradation Degradation of the extracellular matrix Assembly of collagen fibrils and other multimeric structures ECM proteoglycans Integrin cell surface interactions Collagen biosynthesis and modifying enzymes NCAM signaling for neurite out-growth
Drugs
Diseases
GWAS
Protein-Protein Interactions		9 interactors: COL2A1 DCN DNAJB11 FGF7 LAMB1 LGALS3BP MAG PDGFA PDGFB	11 interactors: CD14 COL5A1 COL6A1 FN1 ITGB1 LGALS1 LGALS3 NID1 PPIC SELE XRN1
Entrez ID		1291	3959
HPRD ID		00370	02796
Ensembl ID		ENSG00000142156	ENSG00000108679
Uniprot IDs		P12109	B4DWA8 Q08380
PDB IDs			1BY2
Enriched GO Terms of Interacting Partners?		Extracellular Matrix Organization Extracellular Structure Organization Negative Regulation Of Phosphatidylinositol Biosynthetic Process Positive Regulation Of Metanephric Mesenchymal Cell Migration Positive Regulation Of Metanephric Mesenchymal Cell Migration By Platelet-derived Growth Factor Receptor-beta Signaling Pathway Organ Morphogenesis Negative Regulation Of Phospholipid Biosynthetic Process Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Cellular Response To Growth Factor Stimulus Response To Growth Factor Chemotaxis Locomotion Platelet-derived Growth Factor Receptor-beta Signaling Pathway Response To Wounding Positive Regulation Of Cell Migration Positive Regulation Of Cell Motility Response To Organic Substance Extracellular Matrix Disassembly Positive Regulation Of Cellular Component Movement Positive Regulation Of Locomotion Tissue Development Positive Regulation Of Cell Division Response To External Stimulus Organ Development Regulation Of Branching Involved In Salivary Gland Morphogenesis Positive Regulation Of Protein Autophosphorylation Phosphatidylinositol-mediated Signaling Cellular Response To Organic Substance Negative Regulation Of Platelet Activation Positive Regulation Of Epithelial Cell Proliferation Epidermal Growth Factor Receptor Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Response To Stress Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Regulation Of Cell Migration Wound Healing Positive Chemotaxis Branching Involved In Salivary Gland Morphogenesis Regulation Of Peptidyl-tyrosine Phosphorylation Regulation Of Protein Autophosphorylation Regulation Of Cell Motility Regulation Of Platelet Activation Fc-epsilon Receptor Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Anatomical Structure Morphogenesis Response To Stimulus Regulation Of Locomotion	Extracellular Matrix Organization Extracellular Structure Organization Extracellular Matrix Disassembly Regulation Of Endocytosis Calcium-independent Cell-matrix Adhesion Leukocyte Migration Cell Adhesion Regulation Of Cellular Component Organization Locomotion Response To Wounding Positive Regulation Of Endocytosis Leukocyte Tethering Or Rolling Regulation Of Vesicle-mediated Transport Cell Migration Movement Of Cell Or Subcellular Component Formation Of Primary Germ Layer Cell Motility Cell-matrix Adhesion Response To External Stimulus Regulation Of Cell-substrate Adhesion Cellular Extravasation Gastrulation Cell-substrate Adhesion Wound Healing Chemotaxis Regulation Of Cell Adhesion Endodermal Cell Differentiation Regulation Of Immune System Process Immune System Process Defense Response Cell Morphogenesis Involved In Differentiation Positive Regulation Of Transport Response To Stress Endoderm Formation Positive Regulation Of Cell Migration Generation Of Neurons Collagen Catabolic Process Positive Regulation Of Cell Motility Positive Regulation Of Cellular Component Movement Positive Regulation Of Locomotion Negative Regulation Of Immunological Synapse Formation Integrin Biosynthetic Process Positive Regulation Of Erythrocyte Aggregation Neurogenesis Positive Regulation Of Immune System Process Positive Regulation Of Cell Adhesion Regulation Of Neuron Projection Development Collagen Metabolic Process Tissue Development Axon Guidance
Tagcloud ?		6365g aetiologies bethlem bioinformaticians commercialisation consumer definitively eventual expertise faced flagged geneticists gly2122val hitherto journey myopathy neuromuscular pointed pursued realising reassessment sanger sidetracked son table uncharacterised unprecedented	angptl2 cldn10 cldn4 cst6 dioestrus enpp1 epas1 itgb4 maged1 mep1b metoestrus muc16 oestrogens oestrous oestrus pcsk5 plat preoestrus sepp1 simmental slc11a2 slc16a1 slc1a1 tdgf1 tek timp1 timp2 tjp1
Tagcloud (Difference) ?		6365g aetiologies bethlem bioinformaticians commercialisation consumer definitively eventual expertise faced flagged geneticists gly2122val hitherto journey myopathy neuromuscular pointed pursued realising reassessment sanger sidetracked son table uncharacterised unprecedented	angptl2 cldn10 cldn4 cst6 dioestrus enpp1 epas1 itgb4 maged1 mep1b metoestrus muc16 oestrogens oestrous oestrus pcsk5 plat preoestrus sepp1 simmental slc11a2 slc16a1 slc1a1 tdgf1 tek timp1 timp2 tjp1
Tagcloud (Intersection) ?