COL6A1 and DNAJB11

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		COL6A1	DNAJB11
Gene Name		collagen, type VI, alpha 1	DnaJ (Hsp40) homolog, subfamily B, member 11
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Proteinaceous Extracellular Matrix Collagen Type VI Trimer Lysosomal Membrane Endoplasmic Reticulum Lumen Membrane Extracellular Matrix Sarcolemma Protein Complex Extracellular Vesicular Exosome	Nucleus Endoplasmic Reticulum Endoplasmic Reticulum Lumen Membrane
	Molecular Function	Platelet-derived Growth Factor Binding	Protein Binding Unfolded Protein Binding
	Biological Process	Osteoblast Differentiation Cell Adhesion Axon Guidance Extracellular Matrix Disassembly Extracellular Matrix Organization Collagen Catabolic Process Endodermal Cell Differentiation Protein Heterotrimerization Cellular Response To Amino Acid Stimulus	Protein Folding Activation Of Signaling Protein Activity Involved In Unfolded Protein Response MRNA Modification Endoplasmic Reticulum Unfolded Protein Response Cellular Protein Metabolic Process
Pathways		Signaling by PDGF NCAM1 interactions Collagen formation Axon guidance Collagen degradation Degradation of the extracellular matrix Assembly of collagen fibrils and other multimeric structures ECM proteoglycans Integrin cell surface interactions Collagen biosynthesis and modifying enzymes NCAM signaling for neurite out-growth	IRE1alpha activates chaperones XBP1(S) activates chaperone genes Unfolded Protein Response (UPR)
Drugs
Diseases
GWAS
Protein-Protein Interactions		9 interactors: COL2A1 DCN DNAJB11 FGF7 LAMB1 LGALS3BP MAG PDGFA PDGFB	23 interactors: ANKZF1 APOBEC1 BAG6 CEP70 COL6A1 CRMP1 DDAH2 DNAJC13 DRAP1 EIF3D EZH2 FAF1 GRB2 HSPA1A PAXIP1 PTN SIMC1 SNX5 SPRED1 SUMO4 UBQLN4 UBR1 ZZZ3
Entrez ID		1291	51726
HPRD ID		00370	07485
Ensembl ID		ENSG00000142156	ENSG00000090520
Uniprot IDs		P12109	Q9UBS4
PDB IDs
Enriched GO Terms of Interacting Partners?		Extracellular Matrix Organization Extracellular Structure Organization Negative Regulation Of Phosphatidylinositol Biosynthetic Process Positive Regulation Of Metanephric Mesenchymal Cell Migration Positive Regulation Of Metanephric Mesenchymal Cell Migration By Platelet-derived Growth Factor Receptor-beta Signaling Pathway Organ Morphogenesis Negative Regulation Of Phospholipid Biosynthetic Process Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Cellular Response To Growth Factor Stimulus Response To Growth Factor Chemotaxis Locomotion Platelet-derived Growth Factor Receptor-beta Signaling Pathway Response To Wounding Positive Regulation Of Cell Migration Positive Regulation Of Cell Motility Response To Organic Substance Extracellular Matrix Disassembly Positive Regulation Of Cellular Component Movement Positive Regulation Of Locomotion Tissue Development Positive Regulation Of Cell Division Response To External Stimulus Organ Development Regulation Of Branching Involved In Salivary Gland Morphogenesis Positive Regulation Of Protein Autophosphorylation Phosphatidylinositol-mediated Signaling Cellular Response To Organic Substance Negative Regulation Of Platelet Activation Positive Regulation Of Epithelial Cell Proliferation Epidermal Growth Factor Receptor Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Response To Stress Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Regulation Of Cell Migration Wound Healing Positive Chemotaxis Branching Involved In Salivary Gland Morphogenesis Regulation Of Peptidyl-tyrosine Phosphorylation Regulation Of Protein Autophosphorylation Regulation Of Cell Motility Regulation Of Platelet Activation Fc-epsilon Receptor Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Anatomical Structure Morphogenesis Response To Stimulus Regulation Of Locomotion	Peptidyl-lysine Modification Catabolic Process Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Signal Transduction Response To Ionizing Radiation Regulation Of Protein Metabolic Process Negative Regulation Of Signaling Positive Regulation Of Protein Complex Assembly Posttranscriptional Regulation Of Gene Expression Cellular Response To Organonitrogen Compound Regulation Of Metabolic Process Positive Regulation Of Histone H3-K36 Methylation Cellular Response To Amino Acid Stimulus Cellular Heat Acclimation Regulation Of Early Endosome To Recycling Endosome Transport Cytidine To Uridine Editing Cellular Response To Leucine Formation Of Cytoplasmic Translation Initiation Complex Ossification Positive Regulation Of Cellular Component Biogenesis Negative Regulation Of Methylation-dependent Chromatin Silencing DNA Modification Positive Regulation Of Reactive Oxygen Species Metabolic Process Histone Lysine Methylation Protein Stabilization Regulation Of Protein Complex Assembly Chromatin Organization Signal Transduction In Response To DNA Damage Peptidyl-lysine Methylation Skeletal Muscle Satellite Cell Maintenance Involved In Skeletal Muscle Regeneration Regulation Of Methylation-dependent Chromatin Silencing Locomotion Regulation Of Protein Catabolic Process Axon Guidance Signal Transduction By P53 Class Mediator Response To Amino Acid
Tagcloud ?		6365g aetiologies bethlem bioinformaticians commercialisation consumer definitively eventual expertise faced flagged geneticists gly2122val hitherto journey myopathy neuromuscular pointed pursued realising reassessment sanger sidetracked son table uncharacterised unprecedented	aggregation attenuates chaperoning clients destabilized erdj3 evade extracellular hsp40 indirectly influences links metazoan misfolded overwhelmed preemptively prion prone proteostasis proteotoxic proteotoxicity remodeling revealing secrete secretion space substoichiometrically unfolded upr
Tagcloud (Difference) ?		6365g aetiologies bethlem bioinformaticians commercialisation consumer definitively eventual expertise faced flagged geneticists gly2122val hitherto journey myopathy neuromuscular pointed pursued realising reassessment sanger sidetracked son table uncharacterised unprecedented	aggregation attenuates chaperoning clients destabilized erdj3 evade extracellular hsp40 indirectly influences links metazoan misfolded overwhelmed preemptively prion prone proteostasis proteotoxic proteotoxicity remodeling revealing secrete secretion space substoichiometrically unfolded upr
Tagcloud (Intersection) ?