COL1A2 and COL5A3

Number of citations of the paper that reports this interaction (PMID 10722718)
11

Data Source:
HPRD (in vivo)

		COL1A2	COL5A3
Gene Name		collagen, type I, alpha 2	collagen, type V, alpha 3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Collagen Type I Trimer Extracellular Space Endoplasmic Reticulum Lumen Extracellular Matrix Extracellular Vesicular Exosome	Extracellular Region Collagen Type V Trimer Endoplasmic Reticulum Lumen Extracellular Vesicular Exosome
	Molecular Function	Extracellular Matrix Structural Constituent Protein Binding Protein Binding, Bridging Identical Protein Binding SMAD Binding Metal Ion Binding Platelet-derived Growth Factor Binding	Extracellular Matrix Structural Constituent Collagen Binding Heparin Binding Proteoglycan Binding
	Biological Process	Skeletal System Development Blood Vessel Development Receptor-mediated Endocytosis Transforming Growth Factor Beta Receptor Signaling Pathway Rho Protein Signal Transduction Blood Coagulation Regulation Of Blood Pressure Extracellular Matrix Disassembly Platelet Activation Extracellular Matrix Organization Collagen Fibril Organization Collagen Catabolic Process Odontogenesis Skin Morphogenesis Leukocyte Migration Protein Heterotrimerization Cellular Response To Amino Acid Stimulus	Cell-matrix Adhesion Axon Guidance Extracellular Matrix Disassembly Extracellular Matrix Organization Collagen Fibril Organization Collagen Catabolic Process Skin Development
Pathways		Platelet Adhesion to exposed collagen Collagen formation Collagen degradation Anchoring fibril formation Non-integrin membrane-ECM interactions Degradation of the extracellular matrix Assembly of collagen fibrils and other multimeric structures Cell surface interactions at the vascular wall Syndecan interactions Crosslinking of collagen fibrils ECM proteoglycans GPVI-mediated activation cascade Integrin cell surface interactions Collagen biosynthesis and modifying enzymes Platelet activation, signaling and aggregation Scavenging by Class A Receptors	Signaling by PDGF NCAM1 interactions Collagen formation Axon guidance Collagen degradation Non-integrin membrane-ECM interactions Degradation of the extracellular matrix Assembly of collagen fibrils and other multimeric structures Syndecan interactions ECM proteoglycans Integrin cell surface interactions Collagen biosynthesis and modifying enzymes NCAM signaling for neurite out-growth
Drugs
Diseases
GWAS		Aging ( 22773346) Immune reponse to smallpox (secreted IL-12p40) ( 22610502) Intelligence ( 22449649) Mean forced vital capacity from 2 exams ( 17903307)
Protein-Protein Interactions		24 interactors: APP BGN CD36 CD44 CD93 COL5A3 DCN FN1 ITGA2 ITGA2B ITGB3 LIG4 LUM MMP9 MYOC P4HB PDGFA PDGFB SGTA SHBG SPARC TGFBI UBQLN1 VWF	2 interactors: COL1A2 COL5A1
Entrez ID		1278	50509
HPRD ID		00363	00369
Ensembl ID		ENSG00000164692	ENSG00000080573
Uniprot IDs		P08123	P25940
PDB IDs
Enriched GO Terms of Interacting Partners?		Extracellular Matrix Organization Extracellular Structure Organization Platelet Degranulation Blood Coagulation Wound Healing Hemostasis Platelet Activation Response To Wounding Regulation Of Body Fluid Levels Cell Activation Exocytosis Cell Adhesion Positive Regulation Of Cell Migration Positive Regulation Of Cell Motility Secretion By Cell Positive Regulation Of Cellular Component Movement Positive Regulation Of Locomotion Cell-substrate Adhesion Secretion System Development Cell-matrix Adhesion Anatomical Structure Development Positive Regulation Of Epithelial Cell Migration Extracellular Matrix Disassembly Regulation Of Peptidyl-tyrosine Phosphorylation Regulation Of Cell Migration Chemotaxis Response To Stress Multicellular Organismal Development Developmental Process Regulation Of Cell Motility Organ Development Locomotion Regulation Of Locomotion Regulation Of Cellular Component Movement Glycosaminoglycan Catabolic Process Regulation Of Epithelial Cell Migration Response To External Stimulus Cell Development Response To Abiotic Stimulus Vesicle-mediated Transport Cell Projection Organization Anatomical Structure Morphogenesis Negative Regulation Of Phosphatidylinositol Biosynthetic Process Response To Stimulus Regulation Of Cellular Amino Acid Metabolic Process Axon Guidance Leukocyte Migration Tissue Development Positive Regulation Of Metanephric Mesenchymal Cell Migration	Collagen Fibril Organization Collagen Catabolic Process Collagen Metabolic Process Multicellular Organismal Macromolecule Metabolic Process Multicellular Organismal Metabolic Process Extracellular Matrix Disassembly Integrin Biosynthetic Process Skin Development Negative Regulation Of Endodermal Cell Differentiation Extracellular Matrix Organization Extracellular Structure Organization Blood Vessel Development Vasculature Development Wound Healing Tendon Development Response To Wounding Protein Heterotrimerization Extracellular Fibril Organization Wound Healing, Spreading Of Epidermal Cells Collagen Biosynthetic Process Cell Migration Cardiovascular System Development Cell Motility Organ Morphogenesis Negative Regulation Of Embryonic Development Locomotion Protein Trimerization Regulation Of Gastrulation Wound Healing, Spreading Of Cells Movement Of Cell Or Subcellular Component Skin Morphogenesis Rho Protein Signal Transduction Cellular Response To Amino Acid Stimulus Morphogenesis Of An Epithelial Sheet Catabolic Process Response To Amino Acid Regulation Of Embryonic Development Anatomical Structure Morphogenesis Odontogenesis Protein Heterooligomerization Transforming Growth Factor Beta Receptor Signaling Pathway Eye Morphogenesis Cellular Response To Acid Chemical Regulation Of Blood Pressure Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Platelet Activation Organ Development Ras Protein Signal Transduction Plasma Membrane Organization
Tagcloud ?		archive bcl6 cancerous cebpb checked cufflinks david deg degs downloaded exph5 fastqc hg19 msx2 noiseq paracancerous ppp2r2c read samtools sox4 srp009386 tophat totally transfa trp53 uniquely v1 vcftools
Tagcloud (Difference) ?		archive bcl6 cancerous cebpb checked cufflinks david deg degs downloaded exph5 fastqc hg19 msx2 noiseq paracancerous ppp2r2c read samtools sox4 srp009386 tophat totally transfa trp53 uniquely v1 vcftools
Tagcloud (Intersection) ?