CCL16 and MX1

		CCL16	MX1
Description		C-C motif chemokine ligand 16	MX dynamin like GTPase 1
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Nucleus Nuclear Envelope Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Microtubule Plasma Membrane Membrane Nuclear Membrane Synapse Perinuclear Region Of Cytoplasm Presynapse
	Molecular Function	Cytokine Activity Protein Binding Chemokine Activity Chemoattractant Activity CCR Chemokine Receptor Binding	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Microtubule Binding Identical Protein Binding
	Biological Process	Chemotaxis Inflammatory Response Immune Response Cell Communication Cell-cell Signaling Positive Regulation Of Cell Migration Eosinophil Chemotaxis Positive Chemotaxis Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Chemokine-mediated Signaling Pathway	Immune System Process Apoptotic Process Defense Response Signal Transduction Response To Virus Synaptic Vesicle Budding From Presynaptic Endocytic Zone Membrane Response To Type I Interferon Negative Regulation Of Viral Genome Replication Innate Immune Response Defense Response To Virus Interleukin-27-mediated Signaling Pathway Antiviral Innate Immune Response
Pathways		Chemokine receptors bind chemokines G alpha (i) signalling events	ISG15 antiviral mechanism Interferon alpha/beta signaling
Drugs
Diseases
GWAS		Initial pursuit acceleration ( 29064472)
Interacting Genes		6 interacting genes: CCL5 CCR1 CCR5 CCR8 HRH4 UBQLN2	42 interacting genes: ACTB ADRM1 APP BLM BRD7 C7orf25 CAB39L CASP8AP2 CBX4 CHD3 DAXX EPM2AIP1 FANCA FXR1 GMEB1 HMGXB4 KIF26B KLHL35 LRRC4B MCCD1 PIAS1 PIAS2 PLRG1 PSD3 RELA SIAH1 SIRPA SLC25A3 SP100 TDG TRPC1 TRPC3 TRPC4 TRPC5 TRPC6 TRPC7 TUBA1A TUBB ZBTB16 ZCCHC12 ZNF251 ZNF623
Entrez ID		6360	4599
HPRD ID		03233	00919
Ensembl ID		ENSG00000275152	ENSG00000157601
Uniprot IDs		O15467	H9KVC7 P20591
PDB IDs		5LTL 7SCT 8FK9	3LJB 3SZR 3ZYS 4P4S 4P4T 4P4U 5GTM
Enriched GO Terms of Interacting Partners?		Chemokine Receptor Activity Chemokine-mediated Signaling Pathway Dendritic Cell Migration Dendritic Cell Chemotaxis C-C Chemokine Binding C-C Chemokine Receptor Activity Phosphatidylinositol-4,5-bisphosphate Phospholipase C Activity Chemokine (C-C Motif) Ligand 5 Binding Positive Regulation Of Cytosolic Calcium Ion Concentration Cytokine-mediated Signaling Pathway Cell Chemotaxis Response To Cytokine Response To Peptide Negative Regulation Of Macrophage Apoptotic Process Chemotaxis Mononuclear Cell Migration G Protein-coupled Receptor Signaling Pathway Locomotion G Protein-coupled Receptor Activity Cellular Response To Cytokine Stimulus Leukocyte Chemotaxis Positive Regulation Of Neuroinflammatory Response Negative Regulation Of Myeloid Cell Apoptotic Process Positive Regulation Of Monocyte Chemotaxis Monocyte Chemotaxis Calcium-mediated Signaling Inflammatory Response Regulation Of Monocyte Chemotaxis Regulation Of Myeloid Cell Apoptotic Process Immune Response Cell-cell Signaling Leukocyte Migration Regulation Of Neuroinflammatory Response Signaling Calcium Ion Transport Cell Communication Negative Regulation Of Viral Genome Replication Defense Response G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Negative Regulation Of Leukocyte Apoptotic Process Coreceptor Activity Chemokine Receptor Antagonist Activity Chemokine (C-C Motif) Ligand 5 Signaling Pathway CCR4 Chemokine Receptor Binding Intracellular Signaling Cassette External Side Of Plasma Membrane Negative Regulation Of Viral Process Regulation Of Viral Genome Replication Cell Migration Chemokine (C-C Motif) Ligand 7 Binding	Store-operated Calcium Channel Activity Inositol 1,4,5 Trisphosphate Binding Cation Channel Complex PML Body Regulation Of Cytosolic Calcium Ion Concentration Calcium Channel Activity Transcription Corepressor Activity Cytoplasmic Ribonucleoprotein Granule SUMO Ligase Activity Actinin Binding Negative Regulation Of Cytokine Production Involved In Inflammatory Response Monoatomic Ion Channel Activity Negative Regulation Of Nucleobase-containing Compound Metabolic Process Intracellular Calcium Ion Homeostasis SUMO Transferase Activity Calcium Ion Transmembrane Transport Calcium Ion Homeostasis Regulation Of Presynapse Organization Regulation Of Presynapse Assembly Positive Regulation Of Cell-cell Adhesion Negative Regulation Of RNA Metabolic Process Calcium Ion Transport Regulation Of Cytokine Production Involved In Inflammatory Response Nucleus Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of DNA-templated Transcription Positive Regulation Of Leukocyte Cell-cell Adhesion Regulation Of Cell Development Regulation Of T Cell Activation Identical Protein Binding Regulation Of T Cell Differentiation Intracellular Monoatomic Cation Homeostasis Associative Learning Inorganic Ion Homeostasis Regulation Of Long-term Synaptic Potentiation Negative Regulation Of Macromolecule Biosynthetic Process Protein Homodimerization Activity Intracellular Monoatomic Ion Homeostasis Negative Regulation Of Dendrite Morphogenesis Positive Regulation Of Cell Differentiation Regulation Of Synapse Organization Ubiquitin Protein Ligase Binding Regulation Of Multicellular Organismal Development Positive Regulation Of RNA Metabolic Process Negative Regulation Of Biosynthetic Process Nuclear Envelope Lumen SUMO Binding Synapse Negative Regulation Of Long-term Synaptic Potentiation Positive Regulation Of MiRNA-mediated Gene Silencing
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