MOB2 and STK38

Number of citations of the paper that reports this interaction (PMID 15067004)
19

Data Source:
HPRD (in vitro, in vivo)

		MOB2	STK38
Gene Name		MOB kinase activator 2	serine/threonine kinase 38
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleolus Cytoplasm Neuron Projection Terminus Perinuclear Region Of Cytoplasm	Nucleus Cytoplasm MLL5-L Complex
	Molecular Function	Metal Ion Binding	Magnesium Ion Binding Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Mitogen-activated Protein Kinase Kinase Kinase Binding
	Biological Process	Positive Regulation Of Protein Phosphorylation Positive Regulation Of Neuron Projection Development Actin Cytoskeleton Organization	Cellular Protein Modification Process Protein Phosphorylation Intracellular Signal Transduction Negative Regulation Of MAP Kinase Activity
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		2 interactors: NDRG2 STK38	8 interactors: CALM1 CTDP1 HERC5 MOB2 S100B TRIM25 YWHAB YWHAZ
Entrez ID		81532	11329
HPRD ID		17581	09511
Ensembl ID			ENSG00000112079
Uniprot IDs		Q70IA6	Q15208
PDB IDs			1PSB
Enriched GO Terms of Interacting Partners?		Negative Regulation Of MAPK Cascade Negative Regulation Of Phosphorylation Negative Regulation Of Intracellular Signal Transduction Regulation Of Platelet-derived Growth Factor Production Regulation Of MAPK Cascade Negative Regulation Of Signal Transduction Negative Regulation Of Signaling Negative Regulation Of Smooth Muscle Cell Proliferation Regulation Of Vascular Endothelial Growth Factor Production Regulation Of Phosphorylation Substantia Nigra Development Negative Regulation Of ERK1 And ERK2 Cascade Regulation Of Phosphorus Metabolic Process Neural Nucleus Development Regulation Of Intracellular Signal Transduction Negative Regulation Of MAP Kinase Activity Midbrain Development Regulation Of Smooth Muscle Cell Proliferation Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Protein Serine/threonine Kinase Activity Regulation Of Signal Transduction Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Cytokine Production Regulation Of Signaling	Immune Response Defense Response Innate Immune Response Immune System Process Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Negative Regulation Of Type I Interferon Production Response To Hormone Positive Regulation Of Mitochondrion Organization Response To Stress Regulation Of Protein Phosphorylation Regulation Of Intracellular Transport Response To Steroid Hormone Regulation Of Mitochondrion Organization Positive Regulation Of Signal Transduction Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Phosphorylation Regulation Of Type I Interferon Production Response To Organic Substance Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Regulation Of Dephosphorylation Regulation Of Phosphorus Metabolic Process Positive Regulation Of Cell Death Regulation Of Signal Transduction Regulation Of Viral Process Response To Glucocorticoid Defense Response To Virus Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of Skeletal Muscle Cell Differentiation Golgi Reassembly Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity ERBB Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway Response To Corticosteroid Positive Regulation Of Protein Phosphorylation Positive Regulation Of Transport Regulation Of Signaling Regulation Of Protein Kinase Activity Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of High Voltage-gated Calcium Channel Activity Intrinsic Apoptotic Signaling Pathway Cellular Response To Fibroblast Growth Factor Stimulus Platelet Activation Response To Fibroblast Growth Factor Regulation Of Kinase Activity Response To External Stimulus Negative Regulation Of Protein Dephosphorylation Histamine Secretion By Mast Cell
Tagcloud ?		atm binder biochemically competing damage damaged ddr enigmatic exogenously facilitating hmob1 hmob2 manipulations mechanistic mobs mps mre11 mrn nbs1 ndr ndrs partners performs rad50 revealing sensor signalling supports unexpectedly	asymmetric axon axons cascade depend dynein establishment evolutionarily invertebrates kinases mechanistically morphogenesis ndr ndr1 ndr2 par3 pard3 perform phosphorylating polarity polarization polarized polarizing rassf5 reinforcing ser383 specification supernumerary
Tagcloud (Difference) ?		atm binder biochemically competing damage damaged ddr enigmatic exogenously facilitating hmob1 hmob2 manipulations mechanistic mobs mps mre11 mrn nbs1 ndrs partners performs rad50 revealing sensor signalling supports unexpectedly	asymmetric axon axons cascade depend dynein establishment evolutionarily invertebrates kinases mechanistically morphogenesis ndr1 ndr2 par3 pard3 perform phosphorylating polarity polarization polarized polarizing rassf5 reinforcing ser383 specification supernumerary
Tagcloud (Intersection) ?		ndr