MOB2 and ATG3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MOB2	ATG3
Description		MOB kinase activator 2	autophagy related 3
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Perinuclear Region Of Cytoplasm	Phagophore Assembly Site Cytoplasm Cytosol Atg12-Atg5-Atg16 Complex
	Molecular Function	Protein Binding Protein Kinase Activator Activity Metal Ion Binding	Protein Binding Transferase Activity Atg8-family Ligase Activity Atg12 Transferase Activity Ubiquitin-like Protein Transferase Activity Enzyme Binding Atg8-family Conjugating Enzyme Activity
	Biological Process	Signal Transduction	Autophagosome Assembly Autophagy Of Mitochondrion Protein Targeting To Membrane Autophagy Protein Transport Macroautophagy Protein Ubiquitination Mitochondrial Fragmentation Involved In Apoptotic Process Nucleophagy Negative Regulation Of Phagocytosis Glycophagy Regulation Of Cilium Assembly
Pathways			Macroautophagy
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Myocardial infarction ( 33532862) Prostate cancer ( 29892016) Refractive error ( 32231278)	Asthma (childhood onset) ( 23829686)
Interacting Genes		11 interacting genes: ATG3 CCDC90B FAAP20 FRA10AC1 MIIP NDRG2 NTAQ1 OR5H1 RETREG3 SFT2D2 STK38	6 interacting genes: ATG12 ATG7 GABARAP GABARAPL2 MAP1LC3B MOB2
Entrez ID		81532	64422
HPRD ID		17581	10654
Ensembl ID		ENSG00000182208	ENSG00000144848
Uniprot IDs		Q70IA6	Q9NT62
PDB IDs			4NAW 8AFI 8FKM
Enriched GO Terms of Interacting Partners?			Cellular Response To Nitrogen Starvation Autophagy Of Mitochondrion Autophagosome Assembly Autophagosome Organization Macroautophagy Vacuole Organization Autophagosome Maturation Autophagosome Membrane Mitophagy Autophagosome Autophagy Phosphatidylethanolamine Binding Protein-containing Complex Disassembly Cellular Response To Starvation Response To Starvation Organelle Assembly Cellular Response To Nutrient Levels Axoneme Phospholipid Binding Response To Nutrient Levels GABA Receptor Binding Piecemeal Microautophagy Of The Nucleus Microautophagy Nucleophagy Microtubule Binding Beta-tubulin Binding Catabolic Process Ubiquitin Protein Ligase Binding Regulation Of Protein Catabolic Process Cellular Component Assembly Atg8 Activating Enzyme Activity Atg12 Activating Enzyme Activity Organelle Organization Protein-containing Complex Organization Positive Regulation Of Viral Translation Cellular Response To Stress Cytosol Atg8-family Ligase Activity Positive Regulation Of Protein K48-linked Ubiquitination Cellular Response To Hyperoxia Atg12-Atg5-Atg16 Complex Regulation Of Protein K48-linked Ubiquitination Regulation Of Proteasomal Protein Catabolic Process Cytoplasmic Vesicle Positive Regulation Of Protein Catabolic Process Ceramide Binding Endomembrane System Ubiquitin-like Modifier Activating Enzyme Activity Glycophagy Protein Transport
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