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AP2M1 and H2BC13
Number of citations of the paper that reports this interaction (PubMedID
32296183
)
50
Data Source:
BioGRID
(two hybrid)
AP2M1
H2BC13
Description
adaptor related protein complex 2 subunit mu 1
H2B clustered histone 13
Image
No pdb structure
GO Annotations
Cellular Component
Lysosomal Membrane
Cytosol
Plasma Membrane
Clathrin-coated Pit
Synaptic Vesicle
Cytoplasmic Side Of Plasma Membrane
Membrane
AP-2 Adaptor Complex
Clathrin Adaptor Complex
Endocytic Vesicle Membrane
Clathrin-coated Endocytic Vesicle Membrane
Cytoplasmic Vesicle
Endolysosome Membrane
Synapse
Clathrin-coated Endocytic Vesicle
Extracellular Exosome
Postsynapse
Extrinsic Component Of Presynaptic Endocytic Zone Membrane
Glutamatergic Synapse
Nucleosome
Nucleus
Nucleoplasm
Chromosome
Cytosol
Extracellular Exosome
Molecular Function
Signal Sequence Binding
Protein Binding
Lipid Binding
Clathrin Adaptor Activity
Transmembrane Transporter Binding
Low-density Lipoprotein Particle Receptor Binding
Disordered Domain Specific Binding
DNA Binding
Protein Binding
Structural Constituent Of Chromatin
Protein Heterodimerization Activity
Biological Process
Positive Regulation Of Receptor Internalization
Intracellular Protein Transport
Endocytosis
Vesicle Budding From Membrane
Protein Transport
Vesicle-mediated Transport
Receptor Internalization
Synaptic Vesicle Endocytosis
Protein-containing Complex Assembly
Clathrin-dependent Endocytosis
Regulation Of Vesicle Size
Postsynaptic Neurotransmitter Receptor Internalization
Vesicle-mediated Transport In Synapse
Positive Regulation Of Synaptic Vesicle Endocytosis
Negative Regulation Of Protein Localization To Plasma Membrane
Nucleosome Assembly
Pathways
Nef mediated downregulation of CD28 cell surface expression
Nef Mediated CD4 Down-regulation
Retrograde neurotrophin signalling
Retrograde neurotrophin signalling
Nef Mediated CD8 Down-regulation
Gap junction degradation
Formation of annular gap junctions
MHC class II antigen presentation
EPH-ephrin mediated repulsion of cells
Recycling pathway of L1
Recycling pathway of L1
WNT5A-dependent internalization of FZD4
WNT5A-dependent internalization of FZD2, FZD5 and ROR2
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis
VLDLR internalisation and degradation
LDL clearance
Potential therapeutics for SARS
Recognition and association of DNA glycosylase with site containing an affected pyrimidine
Cleavage of the damaged pyrimidine
Recognition and association of DNA glycosylase with site containing an affected purine
Recognition and association of DNA glycosylase with site containing an affected purine
Cleavage of the damaged purine
Cleavage of the damaged purine
Meiotic synapsis
Packaging Of Telomere Ends
Pre-NOTCH Transcription and Translation
Formation of the beta-catenin:TCF transactivating complex
Formation of the beta-catenin:TCF transactivating complex
PRC2 methylates histones and DNA
Condensation of Prophase Chromosomes
Oxidative Stress Induced Senescence
Senescence-Associated Secretory Phenotype (SASP)
DNA Damage/Telomere Stress Induced Senescence
HDACs deacetylate histones
HATs acetylate histones
HATs acetylate histones
SIRT1 negatively regulates rRNA expression
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression
NoRC negatively regulates rRNA expression
NoRC negatively regulates rRNA expression
B-WICH complex positively regulates rRNA expression
DNA methylation
Transcriptional regulation by small RNAs
Activation of anterior HOX genes in hindbrain development during early embryogenesis
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3
Ub-specific processing proteases
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
Nonhomologous End-Joining (NHEJ)
Processing of DNA double-strand break ends
Deposition of new CENPA-containing nucleosomes at the centromere
Assembly of the ORC complex at the origin of replication
G2/M DNA damage checkpoint
RNA Polymerase I Promoter Opening
RNA Polymerase I Promoter Escape
E3 ubiquitin ligases ubiquitinate target proteins
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
RUNX1 regulates transcription of genes involved in differentiation of HSCs
Estrogen-dependent gene expression
Meiotic recombination
HCMV Early Events
HCMV Late Events
Transcriptional regulation of granulopoiesis
Inhibition of DNA recombination at telomere
Defective pyroptosis
Negative Regulation of CDH1 Gene Transcription
Amyloid fiber formation
Chromatin modifications during the maternal to zygotic transition (MZT)
Replacement of protamines by nucleosomes in the male pronucleus
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
Regulation of endogenous retroelements by KRAB-ZFP proteins
Regulation of endogenous retroelements by KRAB-ZFP proteins
Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex
Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex
Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs)
Regulation of PD-L1(CD274) transcription
Drugs
Diseases
GWAS
Major depressive disorder (
22472876
)
Interacting Genes
86 interacting genes:
ADRA1B
AGTR1
AP2B1
AQP4
ARRB2
ATG9A
ATXN1L
BDKRB2
C1orf35
CACNA1A
CD22
CD2BP2
CD3D
CDK11B
CEBPA
CLK2
CORO7
CSNK2B
CTLA4
CXorf51A
CXorf51B
DAB2
DCX
DPPA2
DVL2
EAF1
EHD2
EIF1AD
FAM90A1
FURIN
FXR2
GAK
GRIN2A
GRIN2B
H2BC10
H2BC13
H2BC21
H2BC4
H2BC6
H2BC7
H2BC8
HEXIM2
HOOK2
HTR6
IKZF1
IRS2
KCNJ11
KNOP1
LAMP1
LTB4R2
LUC7L2
LY9
MAB21L3
MED4
MEGF10
MFAP1
MPP1
MTURN
NAA11
NCOR2
NDRG1
NKAPD1
PRPF18
PRPF38A
PRR13
PTS
RALBP1
RNF111
RPL22
RPL38
RRP12
RSPH14
RUNDC3A
SFRP4
SNCA
SPATS2
STON2
SYNJ1
TASOR
TBC1D5
TGOLN2
TIAM1
TMA16
UBC
ZBTB8A
ZNF581
5 interacting genes:
AP2M1
CDC42
H2AB2
H2AB3
VHL
Entrez ID
1173
8340
HPRD ID
03014
11898
Ensembl ID
ENSG00000161203
ENSG00000185130
Uniprot IDs
B4DNB9
E9PFW3
Q96CW1
Q99880
PDB IDs
1H6E
6BNT
6URI
Enriched GO Terms of Interacting Partners
?
Innate Immune Response In Mucosa
Mucosal Immune Response
Organ Or Tissue Specific Immune Response
Protein-containing Complex Organization
Protein-containing Complex Assembly
Protein Heterodimerization Activity
Structural Constituent Of Chromatin
Antibacterial Humoral Response
Nucleosome Assembly
Protein Domain Specific Binding
Nucleosome
Nucleosome Organization
Protein-DNA Complex Assembly
AP-2 Adaptor Complex
Import Into Cell
Endocytosis
Receptor-mediated Endocytosis
Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide
Defense Response To Gram-positive Bacterium
Synaptic Vesicle Endocytosis
Synaptic Vesicle Uncoating
Presynaptic Endocytosis
Trans-synaptic Signaling
Clathrin Adaptor Activity
Synaptic Signaling
Clathrin Coat Assembly
Nucleoplasm
Positive Regulation Of Receptor-mediated Endocytosis
Clathrin-coated Endocytic Vesicle
Antimicrobial Humoral Response
Positive Regulation Of Endocytosis
Clathrin Coat Disassembly
Regulation Of Neuronal Synaptic Plasticity
Regulation Of Endocytosis
Chemical Synaptic Transmission
Excitatory Postsynaptic Potential
Regulation Of Presynapse Assembly
Regulation Of Presynapse Organization
Vesicle Uncoating
Nucleus
Positive Regulation Of Receptor Internalization
Synaptic Membrane
Protein Binding
Cellular Component Assembly
NMDA Glutamate Receptor Activity
Synapse
Clathrin-dependent Endocytosis
Synaptic Vesicle
Regulation Of Vesicle-mediated Transport
NMDA Selective Glutamate Receptor Complex
Amyloid Fibril Formation
Endothelin Receptor Signaling Pathway Involved In Heart Process
GBD Domain Binding
Storage Vacuole
Cellular Component Assembly
Supramolecular Fiber Organization
Protein-containing Complex Organization
Protein-containing Complex Assembly
Positive Regulation Of Interleukin-6-mediated Signaling Pathway
Ripoptosome Assembly
Death Domain Binding
Ripoptosome Assembly Involved In Necroptotic Process
Nucleosome
Heterochromatin Formation
Nucleosome Assembly
Euchromatin
Nucleosome Organization
Structural Constituent Of Chromatin
Positive Regulation Of Endocytosis
Apolipoprotein A-I Receptor Binding
Neuropilin Signaling Pathway
Signal Sequence Binding
Negative Regulation Of Gene Expression, Epigenetic
Extrinsic Component Of Presynaptic Endocytic Zone Membrane
Positive Regulation Of MiRNA Processing
Peptidyl-serine Autophosphorylation
Protein-DNA Complex Assembly
Positive Regulation Of Pinocytosis
G Protein-coupled Receptor Signaling Pathway Involved In Heart Process
Cardiac Neural Crest Cell Migration Involved In Outflow Tract Morphogenesis
Establishment Of Golgi Localization
Postsynapse
Positive Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis
Positive Regulation Of Synaptic Vesicle Endocytosis
Positive Regulation Of Synaptic Vesicle Recycling
Postsynaptic Neurotransmitter Receptor Internalization
Transcription Elongation Factor Activity
Ripoptosome
Death-inducing Signaling Complex
Positive Regulation Of Necroptotic Process
Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis
JUN Kinase Kinase Kinase Activity
Necroptotic Signaling Pathway
Leading Edge Membrane
Thioesterase Binding
Neuron Fate Determination
Golgi Transport Complex
Positive Regulation Of Programmed Necrotic Cell Death
Epigenetic Regulation Of Gene Expression
Endothelin Receptor Signaling Pathway
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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