AP2M1 and RPL38

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		AP2M1	RPL38
Gene Name		adaptor-related protein complex 2, mu 1 subunit	ribosomal protein L38
Image
Gene Ontology Annotations	Cellular Component	Mitochondrion Lysosomal Membrane Cytosol Plasma Membrane AP-2 Adaptor Complex Endocytic Vesicle Membrane Clathrin-coated Endocytic Vesicle Membrane Extracellular Vesicular Exosome	Cytosol Focal Adhesion Cytosolic Large Ribosomal Subunit Eukaryotic 80S Initiation Complex
	Molecular Function	Signal Sequence Binding Transporter Activity Protein Binding Lipid Binding Clathrin Adaptor Activity Low-density Lipoprotein Particle Receptor Binding	RNA Binding Structural Constituent Of Ribosome
	Biological Process	Intracellular Protein Transport Epidermal Growth Factor Receptor Signaling Pathway Synaptic Transmission Axon Guidance Viral Process Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Neurotrophin TRK Receptor Signaling Pathway Ephrin Receptor Signaling Pathway Regulation Of Defense Response To Virus By Virus Membrane Organization Clathrin-mediated Endocytosis Negative Regulation Of Protein Localization To Plasma Membrane	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Skeletal System Development Ossification Translation Translational Initiation Translational Elongation Translational Termination Regulation Of Translation SRP-dependent Cotranslational Protein Targeting To Membrane Sensory Perception Of Sound Gene Expression Viral Process Viral Life Cycle Viral Transcription 90S Preribosome Assembly Middle Ear Morphogenesis Cellular Protein Metabolic Process Axial Mesoderm Development
Pathways		Retrograde neurotrophin signalling Axon guidance Gap junction degradation HIV Infection Nef Mediated CD8 Down-regulation L1CAM interactions Signaling by Wnt Signaling by EGFRvIII in Cancer Recycling pathway of L1 EPH-ephrin mediated repulsion of cells Gap junction trafficking and regulation MHC class II antigen presentation EPH-Ephrin signaling Nef Mediated CD4 Down-regulation EGFR downregulation Formation of annular gap junctions Signalling by NGF Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters Nef mediated downregulation of CD28 cell surface expression Gap junction trafficking Host Interactions of HIV factors Signaling by Ligand-Responsive EGFR Variants in Cancer The role of Nef in HIV-1 replication and disease pathogenesis NGF signalling via TRKA from the plasma membrane Signaling by Overexpressed Wild-Type EGFR in Cancer beta-catenin independent WNT signaling Signaling by EGFR WNT5A-dependent internalization of FZD4 Signaling by EGFR in Cancer PCP/CE pathway Adaptive Immune System	Nonsense-Mediated Decay (NMD) Translation SRP-dependent cotranslational protein targeting to membrane Eukaryotic Translation Termination Peptide chain elongation Influenza Infection Viral mRNA Translation L13a-mediated translational silencing of Ceruloplasmin expression Influenza Life Cycle Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Influenza Viral RNA Transcription and Replication GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Initiation Formation of a pool of free 40S subunits Eukaryotic Translation Elongation Cap-dependent Translation Initiation Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS		Major depressive disorder ( 22472876)
Protein-Protein Interactions		40 interactors: ADRA1B AP2B1 AQP4 ARRB2 ATXN1L CACNA1A CD22 CD3D CDK11B CORO7 CSNK2B CTLA4 DAB2 DCX DPPA2 DVL2 EHD2 FAM208A FURIN FXR2 GAK GRIN2B IKZF1 KCNJ11 LAMP1 LY9 MED4 MEGF10 NCOR2 NDRG1 RALBP1 RPL38 RRP12 RSPH14 RUNDC3A STON2 SYNJ1 TBC1D5 TGOLN2 ZBTB8A	2 interactors: AP2M1 CHMP5
Entrez ID		1173	6169
HPRD ID		03014	16048
Ensembl ID		ENSG00000161203	ENSG00000172809
Uniprot IDs		E9PFW3 Q96CW1	P63173
PDB IDs		1H6E	3J3B
Enriched GO Terms of Interacting Partners?		Regulation Of Vesicle-mediated Transport Vesicle-mediated Transport Regulation Of Cellular Process System Development Organ Development Endocytosis Signaling Regulation Of Endocytosis Cell Communication Multicellular Organismal Development Anatomical Structure Development Positive Regulation Of Endocytosis Positive Regulation Of Receptor-mediated Endocytosis Transport Protein Localization Developmental Process Positive Regulation Of Transport Cellular Response To Transforming Growth Factor Beta Stimulus Signal Transduction Response To Transforming Growth Factor Beta Cell Differentiation Synaptic Transmission Cell Development Establishment Of Protein Localization Chemotaxis Neurological System Process Regulation Of Signaling Cell-cell Signaling Cellular Response To Stimulus Nervous System Development Positive Regulation Of Receptor Internalization Regulation Of Androgen Receptor Signaling Pathway Establishment Of Localization In Cell Cellular Localization Single-organism Behavior Tube Development Behavioral Response To Pain Regulation Of Natural Killer Cell Mediated Cytotoxicity Cell Morphogenesis Involved In Differentiation Cell Proliferation Regulation Of Metabolic Process Regulation Of Natural Killer Cell Mediated Immunity Regulation Of Membrane Potential Tissue Development Response To Stimulus Response To Estradiol Brain Development Protein Transport Positive Regulation Of Cellular Metabolic Process Regulation Of Receptor Internalization	Viral Process Regulation Of Mitotic Spindle Assembly Regulation Of Spindle Assembly Regulation Of Mitotic Spindle Organization Membrane Organization Cell Separation After Cytokinesis Negative Regulation Of Protein Localization To Plasma Membrane Regulation Of Defense Response To Virus By Virus Mitotic Metaphase Plate Congression Regulation Of Receptor Recycling Endosome To Lysosome Transport Metaphase Plate Congression Clathrin-mediated Endocytosis Regulation Of Centrosome Duplication Protein Transport Establishment Of Chromosome Localization Lysosomal Transport Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Establishment Of Protein Localization Regulation Of Centrosome Cycle Negative Regulation Of ERBB Signaling Pathway Intracellular Transport Regulation Of Protein Localization To Plasma Membrane Lysosome Organization Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Mitotic Sister Chromatid Segregation Protein Localization Vacuolar Transport Regulation Of Cellular Component Organization Regulation Of ERBB Signaling Pathway Regulation Of Defense Response To Virus Establishment Of Localization In Cell Sister Chromatid Segregation Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Ephrin Receptor Signaling Pathway Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Vacuole Organization Nucleus Organization Regulation Of Mitotic Nuclear Division Cellular Localization Regulation Of Microtubule Cytoskeleton Organization Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Regulation Of Microtubule-based Process Viral Life Cycle Regulation Of Signaling Endosomal Transport Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway
Tagcloud ?		chemiluminescent chose escc ftl gearray gearrays gncpro guideline highlighted hla hspa8 immuno iran iranian locate mmp2 modalities modulatory northeast online prove rap1a tailed tp53i3 ube2l6 underexpressed verified verify xrcc5
Tagcloud (Difference) ?		chemiluminescent chose escc ftl gearray gearrays gncpro guideline highlighted hla hspa8 immuno iran iranian locate mmp2 modalities modulatory northeast online prove rap1a tailed tp53i3 ube2l6 underexpressed verified verify xrcc5
Tagcloud (Intersection) ?