SNAP47 and MAGEA6

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		SNAP47	MAGEA6
Description		synaptosome associated protein 47	MAGE family member A6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Endomembrane System Membrane BLOC-1 Complex SNARE Complex Synapse Perinuclear Region Of Cytoplasm Presynapse	Nucleus
	Molecular Function	SNAP Receptor Activity Protein Binding Syntaxin Binding	Protein Binding Histone Deacetylase Binding
	Biological Process	Exocytosis Synaptic Vesicle Priming Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane	Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Autophagy
Pathways
Drugs
Diseases
GWAS		Height ( 28552196) Hip circumference adjusted for BMI ( 34021172) Night sleep phenotypes ( 27126917) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Serum alkaline phosphatase levels ( 33339817)
Interacting Genes		23 interacting genes: APOC2 APOC4 AQP2 CEP57L1 F11R FAM9B FATE1 GOLGA2 KASH5 KLC3 LIME1 LRRC4C MAGEA6 MGST3 MID2 PVR RNF170 SAR1A SPAG5 STX1A STX1B STX4 TRIM59	75 interacting genes: ACOT7 ACTN3 AKAP9 ANKRD26P1 APOA4 ARFIP1 ATOSA ATP6V1G1 ATPAF2 BCL7B BET1 BFSP2 BOLA3 C1orf216 CAMTA2 CBFA2T2 CCDC146 CCDC185 CCDC187 CCDC24 COL4A6 CTF1 DLGAP3 DLGAP4 DNTTIP1 ELMOD3 EXOC5 FRMPD1 GADD45GIP1 GCSH GFOD1 HAUS1 HLA-DRB4 HNRNPM IQUB KIF27 KLHL38 LCORL LIN37 LIN52 LSM2 MCM7 MCRS1 MED21 MID2 MIPOL1 MORN3 MSGN1 NCK2 NOSTRIN PCBD2 PDE4D PRKAA1 RASSF10 RASSF4 RCOR3 REX1BD RPL37A RUSC1 S100A14 S100A9 SH2D4A SMARCD1 SNAP47 SNX4 SON STAMBPL1 STX5 TRIM26 TRIM28 TSPYL6 TULP3 TXNDC9 XRCC4 ZNF76
Entrez ID		116841	4105
HPRD ID		17148	02168
Ensembl ID		ENSG00000143740	ENSG00000197172
Uniprot IDs		A0A087X0B7 Q5SQN1	P43360
PDB IDs
Enriched GO Terms of Interacting Partners?		Microtubule Binding SNAP Receptor Activity SNARE Complex Microtubule Synaptic Vesicle Docking Regulation Of Synaptic Vesicle Priming SNARE Complex Assembly SNARE Binding Vesicle Docking Ciliary Rootlet Organelle Localization By Membrane Tethering Very-low-density Lipoprotein Particle Positive Regulation Of Neurotransmitter Secretion Organelle Localization Schaffer Collateral - CA1 Synapse Membrane Docking Neurotransmitter Transport Vesicle Fusion Organelle Membrane Fusion High-density Lipoprotein Particle Host-mediated Suppression Of Symbiont Invasion Presynaptic Active Zone Membrane Organelle Fusion Vesicle Organization Positive Regulation Of Excitatory Postsynaptic Potential Calcium-ion Regulated Exocytosis Positive Regulation Of Synaptic Transmission Synaptic Vesicle Exocytosis Acylglycerol Homeostasis Triglyceride Homeostasis Spindle Organization Vesicle Docking Involved In Exocytosis Myosin Head/neck Binding Membrane Fusion Sphingomyelin Phosphodiesterase Activator Activity Positive Regulation Of Spontaneous Neurotransmitter Secretion Negative Regulation Of Macropinocytosis Negative Regulation Of Synaptic Vesicle Recycling Identical Protein Binding Intracellular Protein Localization Positive Regulation Of Regulated Secretory Pathway Modulation Of Excitatory Postsynaptic Potential Protein Localization To Cytoskeleton Germ Cell Development Positive Regulation Of Very-low-density Lipoprotein Particle Remodeling Lumenal Side Of Membrane Glycerol Transmembrane Transporter Activity Susceptibility To T Cell Mediated Cytotoxicity Exocytosis Positive Regulation Of Eosinophil Degranulation	Protein Binding SNARE Complex Suppression Of Viral Release By Host
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