CNTROB and HPCAL4

		CNTROB	HPCAL4
Description		centrobin, centriole duplication and spindle assembly protein	hippocalcin like 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centrosome Centriole Cytosol Cytoskeleton Ciliary Basal Body
	Molecular Function	Protein Binding Protein Domain Specific Binding	Calcium Channel Regulator Activity Calcium Ion Binding Protein Binding Protein Domain Specific Binding Metal Ion Binding
	Biological Process	Centriole Replication Centrosome Separation Cell Division Regulation Of Cilium Assembly Mitotic Cytokinetic Process	Central Nervous System Development Response To Heat Regulation Of Signal Transduction
Pathways
Drugs
Diseases
GWAS		Refractive error ( 32231278)	Bone mineral density (Ward's triangle area) ( 27397699)
Interacting Genes		20 interacting genes: APTX COASY CWF19L2 DAPK1 DUSP29 ELOA EPM2AIP1 GSK3A LYST MCRS1 PELI1 PNKP RAD23A RSPH14 SMARCA2 SYT6 TCEA2 TSC1 TSHZ2 TTC23	16 interacting genes: ANKRD33 AQP4 CDSN CEACAM6 DTX2 F3 FAM131C LITAF MSRA SCMH1 SPRED1 TEX13B TRPM5 TSC22D3 TTC12 UBE3A
Entrez ID		116840	51440
HPRD ID		13991	17113
Ensembl ID		ENSG00000170037	ENSG00000116983
Uniprot IDs		Q8N137	B4DGW9 Q9UM19
PDB IDs
Enriched GO Terms of Interacting Partners?		Polynucleotide 3'-phosphatase Activity DNA Metabolic Process DNA Repair Positive Regulation Of DNA Repair Damaged DNA Binding Nucleic Acid Metabolic Process Nucleobase-containing Compound Metabolic Process Negative Regulation Of TOR Signaling Regulation Of DNA Repair Positive Regulation Of Double-strand Break Repair DNA Damage Response Positive Regulation Of DNA Metabolic Process Cellular Response To Stress DAPK1-calmodulin Complex Macromolecule Metabolic Process Positive Regulation Of Autophagic Cell Death Negative Regulation Of UDP-glucose Catabolic Process Regulation Of Glycogen Metabolic Process Regulation Of TOR Signaling Regulation Of Glycogen Biosynthetic Process Response To Insulin Regulation Of Double-strand Break Repair Memory T Cell Differentiation DNA-3'-diphospho-5'-guanosine Diphosphatase Single-strand Break-containing DNA Binding DNA 5'-adenosine Monophosphate Hydrolase Activity Pantetheine-phosphate Adenylyltransferase Activity
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