SYNJ2BP and RALBP1

Number of citations of the paper that reports this interaction (PubMedID 15451561)
0

Data Source:
HPRD (in vitro)

		SYNJ2BP	RALBP1
Description		synaptojanin 2 binding protein	ralA binding protein 1
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Outer Membrane Membrane	Spindle Pole Nucleus Nucleoplasm Cytoplasm Mitochondrion Cytosol Cytoskeleton Plasma Membrane Membrane Nuclear Body
	Molecular Function	Protein Binding	Nucleotide Binding GTPase Activator Activity Protein Binding ATP Binding ABC-type Xenobiotic Transporter Activity ABC-type Glutathione S-conjugate Transporter Activity Transmembrane Transporter Activity Small GTPase Binding ATPase-coupled Transmembrane Transporter Activity Xenobiotic Transmembrane Transporter Activity
	Biological Process	Negative Regulation Of Endothelial Cell Proliferation Protein Targeting Rho Protein Signal Transduction Regulation Of Notch Signaling Pathway Negative Regulation Of Endothelial Cell Migration Negative Regulation Of Angiogenesis Regulation Of Endocytosis Negative Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Sprouting Angiogenesis	Positive Regulation Of Protein Phosphorylation Receptor-mediated Endocytosis Chemotaxis Signal Transduction Small GTPase-mediated Signal Transduction Regulation Of Cdc42 Protein Signal Transduction Regulation Of GTPase Activity Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction Transmembrane Transport Positive Regulation Of Mitochondrial Fission Doxorubicin Transport Xenobiotic Detoxification By Transmembrane Export Across The Plasma Membrane
Pathways			CDC42 GTPase cycle RAC1 GTPase cycle
Drugs
Diseases
GWAS		Blood pressure ( 24954895) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) LDL cholesterol ( 30275531) Motor coordination ( 34177493) Normal facial asymmetry (angle of surface orientation score) ( 30631343)	LDL cholesterol ( 30275531)
Interacting Genes		34 interacting genes: ACTB ACVR2A ACVR2B APP AQP6 CD79A CPLX4 CREB3L1 CYB561 EBP ELOVL5 ELOVL7 ERGIC3 FAM210B FCER1G LHFPL5 LRP1 LRP2 LRP8 MEDAG RALBP1 REEP4 RPS6KA1 SLC10A6 SLC7A8 SYNJ2 THEM5 TLCD4 TMEM101 TMEM14B TMEM242 UBQLN1 USHBP1 VANGL2	46 interacting genes: AMOTL2 AP2M1 C1orf216 CASP8 CBY1 CCDC13 CCDC136 CCDC88B CCHCR1 CCNB1 CEP57 CREBZF DLG4 DRC4 FADD GSE1 HOOK2 HSF1 HSPA13 IKBKG ITSN1 KANK2 LDOC1 MSANTD4 PCM1 PLCG2 PPP1R13B PRKCA RAC1 RALA RALB REPS1 REPS2 RHOU SAPCD2 SMARCE1 SYCE1 SYNJ2BP TBRG1 TCP10L TNIP1 TP53BP2 TRAF2 TSFM ZBTB38 ZNF707
Entrez ID		55333	10928
HPRD ID		15455	09013
Ensembl ID		ENSG00000213463	ENSG00000017797
Uniprot IDs		P57105	Q15311
PDB IDs		2ENO 2JIK 2JIN 7P73 7P74 7PC9 7R2M 7R2T 8AEL	2KWH 2KWI 2MBG 6ZQT 6ZRN
Enriched GO Terms of Interacting Partners?		Membrane Receptor Complex Low-density Lipoprotein Particle Receptor Activity Apolipoprotein Binding Activin Receptor Activity, Type II Activin Receptor Activity Endocytosis Import Into Cell Astrocyte Activation Involved In Immune Response Cargo Receptor Activity Long-chain Fatty-acyl-CoA Metabolic Process Positive Regulation Of Lysosomal Protein Catabolic Process Positive Regulation Of Cell Differentiation Positive Regulation Of Activin Receptor Signaling Pathway Activin Receptor Complex Positive Regulation Of Protein Catabolic Process In The Vacuole Fatty Acid Elongase Activity Fatty Acid Elongation, Polyunsaturated Fatty Acid Fatty Acid Elongation, Monounsaturated Fatty Acid Fatty Acid Elongation, Saturated Fatty Acid Protein Binding Activin Binding Regulation Of Lysosomal Protein Catabolic Process Positive Regulation Of Developmental Process Cellular Response To Growth Factor Stimulus Transmembrane Receptor Protein Serine/threonine Kinase Activity Very Long-chain Fatty Acid Biosynthetic Process Fatty Acid Elongation Apical Protein Localization Response To Growth Factor Clathrin-coated Pit Vesicle-mediated Transport Plasma Membrane Protein Complex Receptor-mediated Endocytosis Retinoid Metabolic Process Regulation Of Developmental Process Gastrulation With Mouth Forming Second Heparan Sulfate Proteoglycan Binding Astrocyte Activation Transport Across Blood-brain Barrier Diterpenoid Metabolic Process Fatty Acid Derivative Metabolic Process Endoplasmic Reticulum Transcytosis Long-chain Fatty-acyl-CoA Biosynthetic Process Regulation Of Amyloid-beta Clearance Regulation Of Cell Differentiation Acyl-CoA Metabolic Process Positive Regulation Of Protein Catabolic Process Regulation Of Response To Endoplasmic Reticulum Stress	Positive Regulation Of Macrophage Differentiation Regulation Of Macrophage Differentiation Regulation Of Endocytosis Protein-macromolecule Adaptor Activity Intracellular Signaling Cassette Endocytosis Cellular Component Assembly Protein Binding Intracellular Signal Transduction Positive Regulation Of Immune System Process Regulation Of Vesicle-mediated Transport Cytosol Positive Regulation Of Execution Phase Of Apoptosis Positive Regulation Of Myeloid Leukocyte Differentiation Regulation Of Receptor-mediated Endocytosis Protein Kinase Binding Cytoplasmic Microtubule Organization Import Into Cell Death Effector Domain Binding Regulation Of Signal Transduction Centrosome Regulation Of Receptor Internalization Protein-containing Complex Organization Tumor Necrosis Factor Receptor Binding Ripoptosome CD95 Death-inducing Signaling Complex Protein-containing Complex Assembly Cell Death Response To Lipopolysaccharide Death-inducing Signaling Complex Positive Regulation Of Leukocyte Differentiation Ubiquitin Protein Ligase Binding Programmed Cell Death Identical Protein Binding Positive Regulation Of Cellular Component Organization Tumor Necrosis Factor Receptor Superfamily Binding Positive Regulation Of Cell Communication Positive Regulation Of Signaling Positive Regulation Of Myeloid Cell Differentiation Microtubule Cytoskeleton Organization Regulation Of Canonical NF-kappaB Signal Transduction Organelle Organization Apoptotic Signaling Pathway Positive Regulation Of Peptide Hormone Secretion TRAIL-activated Apoptotic Signaling Pathway Response To Molecule Of Bacterial Origin Positive Regulation Of Signal Transduction Positive Regulation Of Peptide Secretion Cytoskeleton Organization Regulation Of Cytokine Production
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