MIEN1 and VENTX

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MIEN1	VENTX
Description		migration and invasion enhancer 1	VENT homeobox
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Cytosol Plasma Membrane Cytoplasmic Side Of Plasma Membrane Membrane	Chromatin Nucleus Nucleoplasm
	Molecular Function	Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Protein Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Apoptotic Process Positive Regulation Of Cell Migration Negative Regulation Of Apoptotic Process Positive Regulation Of Filopodium Assembly	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II
Pathways			Senescence-Associated Secretory Phenotype (SASP) Transcriptional Regulation by VENTX
Drugs
Diseases
GWAS		Asthma ( 29273806 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Systemic lupus erythematosus ( 28714469)
Interacting Genes		15 interacting genes: ARID5A DDIT4L GORASP2 HDAC7 HIVEP1 HLX HMGB1 HMGB2 NLGN3 POU6F2 REL RNF126 TRIP6 VENTX ZBTB32	93 interacting genes: ABHD11 ACTMAP ADAMTSL4 ARID5A ARSA ATXN7L1 BATF2 BHLHE40 C10orf55 C1orf94 C6orf15 CEACAM6 CERCAM CES1 CFP CREM CSN3 CTAG1A CTAG1B CYSRT1 DAB1 DAZAP2 FAM168B FAM86C1P GLIS2 HOXC8 HYPK INTS11 IRF9 ITIH6 KRT34 KRTAP10-8 KRTAP11-1 KRTAP12-2 KRTAP12-4 KRTAP13-1 KRTAP19-1 KRTAP19-2 KRTAP19-6 KRTAP19-7 KRTAP21-2 KRTAP22-1 KRTAP26-1 KRTAP3-1 KRTAP3-3 KRTAP6-1 KRTAP6-2 KRTAP6-3 KRTAP8-1 LITAF LYG1 MAGED1 MIEN1 ODAM PLA2G2F PLEKHB1 POU6F2 PRR20A PRR20B PRR20C PRR20D PRR20E RBFOX1 RBPMS RHOXF2 RNF144B RNF4 ROR2 RSKR SLC15A2 SMUG1 SOX14 SPRY4 SYNGAP1 TBX15 TBX19 TBX22 TEKT5 TLE2 TMBIM4 TMEM42 TRIP13 TSC1 UBAP2 UBE2I UBQLN2 USP54 VAC14 VHLL WWOX YPEL3 ZBTB32 ZNF34
Entrez ID		84299	27287
HPRD ID		12681	06197
Ensembl ID		ENSG00000141741	ENSG00000151650
Uniprot IDs		J3KTI2 Q9BRT3	O95231
PDB IDs		2LJK
Enriched GO Terms of Interacting Partners?		DNA Binding Regulation Of Transcription By RNA Polymerase II DNA Geometric Change Supercoiled DNA Binding Regulation Of Interferon-beta Production Regulation Of Nucleobase-containing Compound Metabolic Process DNA Topological Change Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process RAGE Receptor Binding Regulation Of Cytokine Production Negative Regulation Of Transcription By RNA Polymerase II Regulation Of RNA Metabolic Process T-helper 1 Cell Differentiation Regulation Of Non-canonical NF-kappaB Signal Transduction DNA Binding, Bending DNA Conformation Change Four-way Junction DNA Binding V(D)J Recombination Transcription Factor Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Chromatin Regulation Of Type I Interferon Production Negative Regulation Of CD4-positive, Alpha-beta T Cell Differentiation Nuclear Thyroid Hormone Receptor Binding Negative Regulation Of Alpha-beta T Cell Differentiation Regulation Of Primary Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of CD4-positive, Alpha-beta T Cell Activation Inflammatory Response To Antigenic Stimulus Chemoattractant Activity Condensed Chromosome Cellular Response To Lipopolysaccharide Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Sequence-specific DNA Binding T-helper Cell Differentiation Positive Regulation Of Interferon-beta Production DNA-binding Transcription Factor Binding Cellular Response To Molecule Of Bacterial Origin T Cell Differentiation Involved In Immune Response Positive Regulation Of Epithelial Cell Proliferation Regulation Of Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains Somatic Cell DNA Recombination Positive Chemotaxis Transcription Corepressor Activity Negative Regulation Of RNA Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process CD4-positive, Alpha-beta T Cell Differentiation Regulation Of Adaptive Immune Response	Intermediate Filament Keratin Filament Protein Binding
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