TEX14

Description		testis expressed 14, intercellular bridge forming factor
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GO Annotations	Cellular Component	Chromosome, Centromeric Region Kinetochore Chromosome Cytoplasm Midbody Intercellular Bridge Extracellular Exosome
	Molecular Function	Nucleotide Binding Protein Kinase Activity Protein Binding ATP Binding Protein Kinase Binding
	Biological Process	Mitotic Spindle Assembly Checkpoint Signaling Male Meiotic Nuclear Division Attachment Of Spindle Microtubules To Kinetochore Negative Regulation Of Cytokinesis Intercellular Bridge Organization Cell Division Mitotic Sister Chromatid Separation Cellular Response To Leukemia Inhibitory Factor
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Drugs
Diseases
GWAS		Age at first birth ( 34211149) Chronotype ( 30696823) Cognitive function ( 25644384) Estimated glomerular filtration rate ( 31152163) Iron status biomarkers (ferritin levels) ( 25352340) Neutrophil count ( 32888494) Primary tooth development (time to first tooth eruption) ( 23704328) Refractive error ( 32231278) Testicular germ cell tumor ( 23666239 23666240 25877299 28604728 28604732) Type 2 diabetes ( 30054458) White blood cell count ( 32888494)
Interacting Genes		4 interacting genes: DDIT4L LHX3 LMO4 MEOX2
Entrez ID		56155
HPRD ID		12046
Ensembl ID		ENSG00000121101
Uniprot IDs		Q8IWB6
PDB IDs		3WUT 3WUU
Enriched GO Terms of Interacting Partners?		Spinal Cord Motor Neuron Cell Fate Specification Spinal Cord Association Neuron Differentiation Motor Neuron Axon Guidance Neuron Fate Specification Cell Differentiation In Spinal Cord Cell Fate Specification Medial Motor Column Neuron Differentiation Central Nervous System Neuron Differentiation Prolactin Secreting Cell Differentiation Ventral Spinal Cord Interneuron Specification Neuron Projection Guidance Somatotropin Secreting Cell Differentiation Axon Guidance Ventral Spinal Cord Interneuron Differentiation Somite Specification Transcription Regulator Complex Positive Regulation Of Transcription By RNA Polymerase II Thyroid-stimulating Hormone-secreting Cell Differentiation Gland Development Neuron Differentiation DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Pattern Specification Process Segment Specification Positive Regulation Of DNA-templated Transcription Somite Development Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of RNA Metabolic Process Sequence-specific DNA Binding Neuron Projection Development Neuroendocrine Cell Differentiation Spinal Cord Motor Neuron Differentiation Regulation Of Cell Fate Specification Positive Regulation Of Nucleobase-containing Compound Metabolic Process Glandular Epithelial Cell Differentiation Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Pituitary Gland Development Ventricular Septum Development Neuroepithelial Cell Differentiation Forebrain Neuron Differentiation Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Cell Migration Involved In Sprouting Angiogenesis Limb Development Anatomical Structure Formation Involved In Morphogenesis Tissue Development Negative Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Transcription By RNA Polymerase II Transcription Coregulator Binding Transcription Coactivator Binding Placenta Development Cardiac Septum Development
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