SFT2D1 and DERL2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SFT2D1	DERL2
Description		SFT2 domain containing 1	derlin 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endomembrane System Membrane	Early Endosome Late Endosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane
	Molecular Function	Protein Binding	Signal Recognition Particle Binding Protein Binding Protein-containing Complex Binding
	Biological Process	Protein Transport Vesicle-mediated Transport	Suckling Behavior Response To Unfolded Protein Positive Regulation Of Cell Population Proliferation Positive Regulation Of Cell Growth Endoplasmic Reticulum Unfolded Protein Response Retrograde Protein Transport, ER To Cytosol ERAD Pathway Negative Regulation Of Retrograde Protein Transport, ER To Cytosol
Pathways			ABC-family proteins mediated transport Hedgehog ligand biogenesis Hh mutants are degraded by ERAD Defective CFTR causes cystic fibrosis ER Quality Control Compartment (ERQC) AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274)
Drugs
Diseases
GWAS			Asparaginase hypersensitivity in acute lymphoblastic leukemia ( 25987655)
Interacting Genes		26 interacting genes: AQP6 ARFIP1 CERCAM DERL2 DIABLO MIEF2 MYG1 OTULIN PLEKHB2 PNKP REEP4 RETREG3 SCAND1 SCN3B SDCBP SLC10A1 SLC30A8 SNX1 SPG21 STOM SYT16 TBRG4 TMEM14B TMEM255B TMEM86B TMX2	12 interacting genes: DIABLO FXYD6 KRTAP10-3 KRTAP10-7 KRTAP10-8 LMNA MELTF MPP1 PTPN9 RBFA SERPINA1 SFT2D1
Entrez ID		113402	51009
HPRD ID		12903	16796
Ensembl ID		ENSG00000198818	ENSG00000072849
Uniprot IDs		Q8WV19	I3L3R8 Q9GZP9
PDB IDs
Enriched GO Terms of Interacting Partners?			Intermediate Filament Keratin Filament
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