DERL2 and RBFA

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		DERL2	RBFA
Description		derlin 2	ribosome binding factor A
Image		No pdb structure
GO Annotations	Cellular Component	Early Endosome Late Endosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane	Mitochondrion
	Molecular Function	Signal Recognition Particle Binding Protein Binding Protein-containing Complex Binding	Protein Binding
	Biological Process	Suckling Behavior Response To Unfolded Protein Positive Regulation Of Cell Population Proliferation Positive Regulation Of Cell Growth Endoplasmic Reticulum Unfolded Protein Response Retrograde Protein Transport, ER To Cytosol ERAD Pathway Negative Regulation Of Retrograde Protein Transport, ER To Cytosol	RRNA Processing Biological_process
Pathways		ABC-family proteins mediated transport Hedgehog ligand biogenesis Hh mutants are degraded by ERAD Defective CFTR causes cystic fibrosis ER Quality Control Compartment (ERQC) AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274)
Drugs
Diseases
GWAS		Asparaginase hypersensitivity in acute lymphoblastic leukemia ( 25987655)
Interacting Genes		12 interacting genes: DIABLO FXYD6 KRTAP10-3 KRTAP10-7 KRTAP10-8 LMNA MELTF MPP1 PTPN9 RBFA SERPINA1 SFT2D1	22 interacting genes: ABHD5 AGTRAP ANK1 CACFD1 CAV3 CMTM5 CMTM6 DERL2 ERLIN1 FATE1 FKBP7 GPR152 GPX8 HIGD1C LEPROTL1 MDK PEX12 RHEX SMIM5 SYP SYPL1 YIF1A
Entrez ID		51009	79863
HPRD ID		16796	07959
Ensembl ID		ENSG00000072849	ENSG00000101546
Uniprot IDs		I3L3R8 Q9GZP9	Q8N0V3
PDB IDs			2E7G 7PNX 7PNY 7PNZ 7PO0 7X9U 8CSR 8CSS 8CST 8CSU 8IPL 8IPM
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament	Membrane
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