SFT2D1 and MIEF2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SFT2D1	MIEF2
Description		SFT2 domain containing 1	mitochondrial elongation factor 2
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endomembrane System Membrane	Mitochondrion Mitochondrial Outer Membrane Peroxisome Membrane
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Protein Transport Vesicle-mediated Transport	Mitochondrion Organization Mitochondrial Fusion Regulation Of Mitochondrion Organization Positive Regulation Of Mitochondrial Fission Positive Regulation Of Protein Targeting To Membrane
Pathways
Drugs
Diseases
GWAS			Change in neurofilament light levels ( 31295725)
Interacting Genes		26 interacting genes: AQP6 ARFIP1 CERCAM DERL2 DIABLO MIEF2 MYG1 OTULIN PLEKHB2 PNKP REEP4 RETREG3 SCAND1 SCN3B SDCBP SLC10A1 SLC30A8 SNX1 SPG21 STOM SYT16 TBRG4 TMEM14B TMEM255B TMEM86B TMX2	30 interacting genes: AGTRAP ARFIP2 ARL6IP1 ATP5PF CIDEA DNM1L FAM114A2 FAM25A FAM25C FAM25G FKBP7 GSG1 HSD17B13 LIME1 MDK NCALD NCS1 PRB2 PSMF1 RABAC1 REEP6 RHBDD2 SFT2D1 SYP TMEM239 UBQLN1 UBQLN2 UBQLN4 YIF1A ZNF628
Entrez ID		113402	125170
HPRD ID		12903	18074
Ensembl ID		ENSG00000198818	ENSG00000177427
Uniprot IDs		Q8WV19	Q96C03
PDB IDs			5WP9
Enriched GO Terms of Interacting Partners?			Endoplasmic Reticulum Polyubiquitin Modification-dependent Protein Binding Cytoplasmic Vesicle Perinuclear Region Of Cytoplasm Endoplasmic Reticulum Organization Regulation Of Proteasomal Protein Catabolic Process Endoplasmic Reticulum Membrane Regulation Of Macroautophagy Autophagosome Positive Regulation Of ERAD Pathway GTP-dependent Protein Binding ERAD Pathway
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