DERL2

Gene Name		derlin 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Early Endosome Late Endosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Endoplasmic Reticulum Membrane
	Molecular Function	Protein Binding
	Biological Process	Suckling Behavior Positive Regulation Of Cell Proliferation Positive Regulation Of Cell Growth ER-associated Ubiquitin-dependent Protein Catabolic Process Endoplasmic Reticulum Unfolded Protein Response Retrograde Protein Transport, ER To Cytosol
Pathways		Hedgehog ligand biogenesis Processing-defective Hh variants abrogate ligand secretion Hh ligand biogenesis disease Signaling by Hedgehog
Drugs
Diseases
GWAS
Protein-protein Interactions		5 interactors: KRTAP10-3 KRTAP10-7 KRTAP10-8 MFI2 SERPINA1
Entrez ID		51009
HPRD ID		16796
Ensembl ID
Uniprot IDs		Q9GZP9
PDB IDs
Enriched GO Terms of Interacting Partners?		Response To Methanol Response To Triglyceride Regulation Of Protein Processing Response To Chromate Positive Regulation Of Extracellular Matrix Disassembly Positive Regulation Of Plasminogen Activation Negative Regulation Of Serine-type Endopeptidase Activity Negative Regulation Of Serine-type Peptidase Activity Negative Regulation Of Substrate Adhesion-dependent Cell Spreading Iron Ion Import Positive Regulation Of Protein Processing Response To Lead Ion Regulation Of Extracellular Matrix Disassembly Regulation Of Substrate Adhesion-dependent Cell Spreading Regulation Of Extracellular Matrix Organization Acute-phase Response Negative Regulation Of Cell-substrate Adhesion Platelet Degranulation Acute Inflammatory Response Iron Ion Transport Cellular Iron Ion Homeostasis Negative Regulation Of Cell Morphogenesis Involved In Differentiation Regulation Of Protein Metabolic Process Iron Ion Homeostasis Response To Estradiol Transition Metal Ion Homeostasis
Tagcloud ?		apparatus cdt cdts chimeras complementation cytolethal derl1 derlin dispensable distending ducreyi erad evasion exit exotoxins exploited haemophilus hrd1 intoxication p97 reaching retrograde retrotranslocation ricin toxins trafficked uncharacterized undescribed wr