DERL2

Description		derlin 2
Image		No pdb structure
GO Annotations	Cellular Component	Early Endosome Late Endosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane
	Molecular Function	Signal Recognition Particle Binding Protein Binding Protein-containing Complex Binding
	Biological Process	Suckling Behavior Response To Unfolded Protein Positive Regulation Of Cell Population Proliferation Positive Regulation Of Cell Growth Endoplasmic Reticulum Unfolded Protein Response Retrograde Protein Transport, ER To Cytosol ERAD Pathway Negative Regulation Of Retrograde Protein Transport, ER To Cytosol
Pathways		ABC-family proteins mediated transport Hedgehog ligand biogenesis Hh mutants are degraded by ERAD Defective CFTR causes cystic fibrosis ER Quality Control Compartment (ERQC) AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274)
Drugs
Diseases
GWAS		Asparaginase hypersensitivity in acute lymphoblastic leukemia ( 25987655)
Novel Interacting Genes		1 novel interacting genes: MMS22L
Interacting Genes		12 interacting genes: DIABLO FXYD6 KRTAP10-3 KRTAP10-7 KRTAP10-8 LMNA MELTF MPP1 PTPN9 RBFA SERPINA1 SFT2D1
Entrez ID		51009
HPRD ID		16796
Ensembl ID		ENSG00000072849
Uniprot IDs		I3L3R8 Q9GZP9
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament
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