CTRC and GIPC2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CTRC	GIPC2
Description		chymotrypsin C	GIPC PDZ domain containing family member 2
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GO Annotations	Cellular Component		Cytoplasm Extracellular Exosome
	Molecular Function	Serine-type Endopeptidase Activity Protein Binding Peptidase Activity Serine-type Peptidase Activity Hydrolase Activity	Protein Binding Identical Protein Binding
	Biological Process	Proteolysis Intracellular Calcium Ion Homeostasis
Pathways		Developmental Lineage of Pancreatic Acinar Cells
Drugs
Diseases		Hereditary pancreatitis; Hereditary chronic pancreatitis Tropical calcific pancreatitis
GWAS		Alcoholic chronic pancreatitis ( 28754779)	Age at first birth ( 34211149) Body mass index ( 29273807) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) End-stage kidney disease ( 31178898) Hand grip strength ( 29691431) Height ( 20881960 25282103) High light scatter reticulocyte percentage of red cells ( 32888494) Hip circumference ( 25673412) Lung adenocarcinoma ( 28604730) Lung cancer ( 28604730) Lung cancer in ever smokers ( 28604730) Mean corpuscular hemoglobin concentration ( 32888494) Platelet distribution width ( 32888494) Post bronchodilator FEV1 ( 26634245) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Severe influenza A (H1N1) infection ( 26379185)
Interacting Genes		20 interacting genes: CYSRT1 GIPC2 KRT34 KRTAP1-1 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP3-1 KRTAP6-2 KRTAP9-2 MDFI NEDD8 NFKBID PHKG1 SERPINA3 SPINK1 SPMIP9 ST13 UBC VGLL3	14 interacting genes: CTRC FZD3 IGSF21 IRF4 LZTS2 PATJ PLEKHA2 PTN SETDB1 SP100 UBE2I UNC119 ZBTB26 ZCCHC7
Entrez ID		11330	54810
HPRD ID		03242	17040
Ensembl ID		ENSG00000162438	ENSG00000137960
Uniprot IDs		Q99895	A0A384P5H2 Q8TF65
PDB IDs		4H4F	3GGE
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament Protein Tag Activity
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