CTRC and KRTAP3-1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CTRC	KRTAP3-1
Description		chymotrypsin C	keratin associated protein 3-1
Image			No pdb structure
GO Annotations	Cellular Component		Cytosol Intermediate Filament Keratin Filament
	Molecular Function	Serine-type Endopeptidase Activity Protein Binding Peptidase Activity Serine-type Peptidase Activity Hydrolase Activity	Structural Molecule Activity Protein Binding
	Biological Process	Proteolysis Intracellular Calcium Ion Homeostasis
Pathways		Developmental Lineage of Pancreatic Acinar Cells	Keratinization
Drugs
Diseases		Hereditary pancreatitis; Hereditary chronic pancreatitis Tropical calcific pancreatitis
GWAS		Alcoholic chronic pancreatitis ( 28754779)
Interacting Genes		20 interacting genes: CYSRT1 GIPC2 KRT34 KRTAP1-1 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP3-1 KRTAP6-2 KRTAP9-2 MDFI NEDD8 NFKBID PHKG1 SERPINA3 SPINK1 SPMIP9 ST13 UBC VGLL3	83 interacting genes: ADAM12 AGXT ANAPC11 BMP7 CDKN1A CELA2B CERK CFP CIMIP1 CNNM3 CREB5 CTRC CYSRT1 DMRT3 DOCK2 FAM168A FAM222B FOXH1 FRS3 GATA2 GNE GPS2 GSTP1 HCK HEY2 HOXB9 HR HSF4 IL16 ITGB4 KRTAP10-8 KRTAP13-2 KRTAP13-3 KRTAP15-1 KRTAP26-1 KRTAP4-11 KRTAP4-12 KRTAP6-1 KRTAP9-3 KRTAP9-8 LCE1B LCE2B LCE3A LCE3D LCE4A LCE5A LMO4 LRRC41 MAPKBP1 MRPL40 MYPOP NOTCH2NLA NTAQ1 OTX1 PATZ1 PCSK5 PHLDA1 PKIB PLSCR4 POLR1C PTPMT1 PVR RBPMS RECK REEP6 RNF44 SAMD7 SAXO4 SLC5A5 SMARCC1 SPAG8 SPMIP9 TEKT3 TLX3 TNS2 VASN VENTX VGLL3 WDR25 YPEL3 ZFHX2 ZNF414 ZNF446
Entrez ID		11330	83896
HPRD ID		03242	13937
Ensembl ID		ENSG00000162438	ENSG00000212901
Uniprot IDs		Q99895	Q9BYR8
PDB IDs		4H4F
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament Protein Tag Activity	Intermediate Filament Protein Binding Keratinization Keratin Filament Epidermis Development Axonemal A Tubule Inner Sheath Tissue Development Ventral Spinal Cord Interneuron Differentiation Heart Trabecula Morphogenesis Cellular Response To Cell-matrix Adhesion
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