CTRC and ST13

Number of citations of the paper that reports this interaction (PubMedID 11687574)
0

Data Source:
BioGRID (enzymatic study)

		CTRC	ST13
Description		chymotrypsin C	ST13 Hsp70 interacting protein
Image			No pdb structure
GO Annotations	Cellular Component		Cytoplasm Cytosol Extracellular Exosome
	Molecular Function	Serine-type Endopeptidase Activity Protein Binding Peptidase Activity Serine-type Peptidase Activity Hydrolase Activity	Protein Binding Hsp70 Protein Binding Protein-macromolecule Adaptor Activity Protein Dimerization Activity
	Biological Process	Proteolysis Intracellular Calcium Ion Homeostasis	Protein Folding Response To Bacterium
Pathways		Developmental Lineage of Pancreatic Acinar Cells	Regulation of HSF1-mediated heat shock response
Drugs
Diseases		Hereditary pancreatitis; Hereditary chronic pancreatitis Tropical calcific pancreatitis
GWAS		Alcoholic chronic pancreatitis ( 28754779)	Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Feeling nervous ( 29500382) Refractive error ( 32231278)
Interacting Genes		20 interacting genes: CYSRT1 GIPC2 KRT34 KRTAP1-1 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP3-1 KRTAP6-2 KRTAP9-2 MDFI NEDD8 NFKBID PHKG1 SERPINA3 SPINK1 SPMIP9 ST13 UBC VGLL3	25 interacting genes: ALB APOE ASF1A CD101 CDC42 CTRC CXCR2 F2 GRIK1 HSP90AA1 HSPA1A HSPA1B HSPA4 HSPA8 NOS3 OGT OLFM2 PSEN1 PTGER4 RBFOX2 SMAD2 SNCA SRSF8 TTR VAV2
Entrez ID		11330	6767
HPRD ID		03242	08426
Ensembl ID		ENSG00000162438	ENSG00000100380
Uniprot IDs		Q99895	A0A140VKA6 B4E0U6 P50502 Q0IJ56
PDB IDs		4H4F
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament Protein Tag Activity	ATP-dependent Protein Folding Chaperone Protein-containing Complex Regulation Of Protein-containing Complex Assembly Blood Microparticle C3HC4-type RING Finger Domain Binding Regulation Of Biological Quality Regulation Of Supramolecular Fiber Organization ATP-dependent Protein Disaggregase Activity Protein Refolding Negative Regulation Of Cellular Component Organization Tau Protein Binding Regulation Of Protein Catabolic Process Negative Regulation Of Protein-containing Complex Assembly Protein Folding Chaperone Intracellular Signal Transduction Negative Regulation Of Platelet Activation Inclusion Body Response To Stress Regulation Of Inclusion Body Assembly Positive Regulation Of Supramolecular Fiber Organization Chaperone-mediated Protein Complex Assembly Signal Transduction Disordered Domain Specific Binding Response To Unfolded Protein Response To Heat Positive Regulation Of Multicellular Organismal Process Positive Regulation Of Proteolysis Regulation Of Proteasomal Protein Catabolic Process Protein Folding Positive Regulation Of Protein Catabolic Process Calcium Ion Homeostasis Regulation Of Proteolysis Aggresome Negative Regulation Of Protein Metabolic Process Positive Regulation Of Signaling Intracellular Signaling Cassette Positive Regulation Of Amyloid Fibril Formation Unfolded Protein Binding Response To Hormone Ficolin-1-rich Granule Lumen Positive Regulation Of Nucleotide-binding Oligomerization Domain Containing 2 Signaling Pathway Cellular Heat Acclimation Receptor Ligand Activity Regulation Of Immune System Process Chaperone-mediated Autophagy Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Blood Coagulation Negative Regulation Of Hemostasis Cellular Response To Heat Positive Regulation Of Microtubule Nucleation
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