EIF4G3 and WDR37

Number of citations of the paper that reports this interaction (PubMedID 34642815)
38

Data Source:
BioGRID (two hybrid)

		EIF4G3	WDR37
Description		eukaryotic translation initiation factor 4 gamma 3	WD repeat domain 37
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Eukaryotic Translation Initiation Factor 4F Complex	Nucleus Cytoplasm
	Molecular Function	RNA Cap Binding RNA Binding MRNA Binding Translation Initiation Factor Activity Protein Binding Translation Factor Activity, RNA Binding	Protein Binding
	Biological Process	Translation Translational Initiation Regulation Of Translation Regulation Of Translational Initiation Spermatid Development Negative Regulation Of Autophagy Positive Regulation Of Translation	Lymphocyte Homeostasis Corpus Callosum Development
Pathways		ISG15 antiviral mechanism
Drugs
Diseases
GWAS		Basophil count ( 32888494) Basophil percentage of white cells ( 32888494) Chronotype ( 30696823) Cognitive decline rate in late mild cognitive impairment ( 26252872) Eosinophil count ( 32888494) Eosinophil percentage of white cells ( 32888494) General risk tolerance (MTAG) ( 30643258) Mean spheric corpuscular volume ( 32888494) Morning person ( 30696823) Postoperative acute renal failure after cardiac surgery ( 30678657) Red blood cell count ( 32888494) Social science traits (pleiotropy) (HIPO component 1) ( 30289880) Superior frontal gyrus grey matter volume ( 25335168)	Chronic kidney disease ( 20383146 26831199) Estimated glomerular filtration rate ( 30604766 31015462) Glomerular filtration rate (creatinine) ( 26831199 28452372) Glomerular filtration rate in non diabetics (creatinine) ( 26831199) Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010)
Interacting Genes		17 interacting genes: CAMK1 CTNND1 DDX19B EIF4A1 EIF4E HSPB1 LIG4 LSM3 MKNK1 PABPC1 PCNT PSMB6 RNF10 TRIM25 VAV2 VPS25 WDR37	5 interacting genes: COL12A1 EIF4G3 EWSR1 MEOX2 TRIP11
Entrez ID		8672	22884
HPRD ID		06802	15668
Ensembl ID		ENSG00000075151	ENSG00000047056
Uniprot IDs		A0A0A0MSA7 A0A804HJV5 A0A8I5QJH9 A0A8J9G7U8 B4DXR2 O43432 Q59GJ0	Q9Y2I8
PDB IDs		1HU3
Enriched GO Terms of Interacting Partners?		Cytoplasmic Stress Granule Nucleus Cytoplasm RNA Cap Binding Eukaryotic Translation Initiation Factor 4F Complex Cytosol Calcium/calmodulin-dependent Protein Kinase Activity Extracellular Exosome RNA Binding Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Translation
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