EIF4G3

Gene Name		eukaryotic translation initiation factor 4 gamma, 3
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Gene Ontology Annotations	Cellular Component	Cytosol Eukaryotic Translation Initiation Factor 4F Complex
	Molecular Function	RNA Cap Binding Translation Initiation Factor Activity Translation Factor Activity, Nucleic Acid Binding Poly(A) RNA Binding
	Biological Process	Translational Initiation Regulation Of Translational Initiation Viral Process Cytokine-mediated Signaling Pathway
Pathways		ISG15 antiviral mechanism Interferon Signaling Cytokine Signaling in Immune system Antiviral mechanism by IFN-stimulated genes
Drugs
Diseases
GWAS
Protein-protein Interactions		7 interactors: CAMK1 EIF4A1 EIF4E LIG4 MKNK1 PABPC1 VAV2
Entrez ID		8672
HPRD ID		06802
Ensembl ID		ENSG00000075151
Uniprot IDs		O43432 Q504Z1 Q59GJ0
PDB IDs		1HU3
Enriched GO Terms of Interacting Partners?		Nuclear-transcribed MRNA Poly(A) Tail Shortening Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay MRNA 3'-end Processing RNA 3'-end Processing Nuclear-transcribed MRNA Catabolic Process MRNA Catabolic Process RNA Catabolic Process Translational Initiation Regulation Of Translation MRNA Processing Aromatic Compound Catabolic Process Posttranscriptional Regulation Of Gene Expression DNA Ligation Involved In DNA Recombination MRNA Metabolic Process Viral Process RNA Processing Translation Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cellular Response To Organic Substance Negative Regulation Of Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Synapse Structural Plasticity Cellular Macromolecule Catabolic Process Lagging Strand Elongation Pro-B Cell Differentiation Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Protein Metabolic Process Apoptotic Process Establishment Of Integrated Proviral Latency Programmed Cell Death Cellular Response To Stimulus Nucleocytoplasmic Transport System Development Nuclear Transport Cell Death Death Immunoglobulin V(D)J Recombination Establishment Of Viral Latency T Cell Receptor V(D)J Recombination DNA Ligation Involved In DNA Repair Cellular Protein Metabolic Process Positive Regulation Of Nuclear-transcribed MRNA Poly(A) Tail Shortening Regulation Of Synapse Structural Plasticity Response To Organic Substance Lymphoid Progenitor Cell Differentiation Positive Regulation Of Protein Export From Nucleus DNA Ligation Apoptotic Signaling Pathway Positive Regulation Of MRNA 3'-end Processing Positive Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay
Tagcloud ?		absent aminopeptidase anpep antigen autoregulatory controlling deaf1 deformed degrades diminished encodes fine histocompatibility ko lnscs lymph maintaining mhc nodes peripheral polysome profiling protease pta stromal t1d translation tuning