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DCTN3 and DCTN1
Number of citations of the paper that reports this interaction (PMID
9722614
)
18
Data Source:
HPRD
(in vitro)
DCTN3
DCTN1
Gene Name
dynactin 3 (p22)
dynactin 1
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Condensed Chromosome Kinetochore
Centrosome
Spindle
Cytosol
Dynactin Complex
Midbody
Cleavage Furrow
Perinuclear Region Of Cytoplasm
Kinetochore
Spindle Pole
Cytoplasm
Centrosome
Cytosol
Dynactin Complex
Microtubule
Membrane
Dynein Complex
Retromer Complex
Cell Leading Edge
Molecular Function
Structural Molecule Activity
Protein Binding
Motor Activity
Protein Binding
Dynein Binding
Biological Process
G2/M Transition Of Mitotic Cell Cycle
Mitotic Cell Cycle
Cytokinesis
Organelle Organization
Microtubule-based Process
Mitotic Nuclear Division
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
G2/M Transition Of Mitotic Cell Cycle
Mitotic Cell Cycle
Activation Of Signaling Protein Activity Involved In Unfolded Protein Response
Organelle Organization
Mitotic Nuclear Division
Nervous System Development
Microtubule-based Transport
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Endoplasmic Reticulum Unfolded Protein Response
Melanosome Transport
Retrograde Transport, Endosome To Golgi
Cellular Protein Metabolic Process
Pathways
Organelle biogenesis and maintenance
Assembly of the primary cilium
G2/M Transition
Anchoring of the basal body to the plasma membrane
Regulation of PLK1 Activity at G2/M Transition
Cell Cycle, Mitotic
Loss of proteins required for interphase microtubule organization from the centrosome
Loss of Nlp from mitotic centrosomes
MHC class II antigen presentation
Centrosome maturation
Mitotic G2-G2/M phases
Recruitment of mitotic centrosome proteins and complexes
Adaptive Immune System
IRE1alpha activates chaperones
MHC class II antigen presentation
XBP1(S) activates chaperone genes
Unfolded Protein Response (UPR)
Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions
4 interactors:
ATXN1
DCTN1
GSK3B
PBX2
42 interactors:
ACTR1A
ACTR1B
AKT1
APEX1
BBS1
BBS4
BICD1
BICD2
CASP2
CASP3
CASP7
CDC37
CLIP1
DCTN3
DISC1
DST
DTNBP1
DYNC1I2
FBXL5
GRB2
GSK3B
HAP1
KIAA0408
KIF11
MAP2K3
MAP2K6
MAPRE1
MED14
MTERF1
NEK2
PAFAH1B1
PFDN1
PGAM1
PPP1CA
RAB6A
RBL2
RPGR
SEC23A
SPTBN2
STAT1
VIM
ZNF512B
Entrez ID
11258
1639
HPRD ID
06303
07206
Ensembl ID
ENSG00000137100
ENSG00000204843
Uniprot IDs
O75935
Q14203
Q6MZZ3
PDB IDs
1TXQ
2COY
2HKN
2HKQ
2HL3
2HL5
2HQH
3E2U
3TQ7
Enriched GO Terms of Interacting Partners
?
ER-nucleus Signaling Pathway
Positive Regulation Of Cellular Metabolic Process
Nuclear Export
Response To Endoplasmic Reticulum Stress
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of Type B Pancreatic Cell Development
Superior Temporal Gyrus Development
Positive Regulation Of Metabolic Process
Re-entry Into Mitotic Cell Cycle
Negative Regulation Of Neuron Maturation
Hypermethylation Of CpG Island
Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Apoptotic Process
Regulation Of Phosphorylation
Positive Regulation Of Transcription, DNA-templated
Nucleocytoplasmic Transport
Nuclear Transport
Cellular Response To Interleukin-3
Regulation Of Phosphorus Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Intracellular Transport
Positive Regulation Of Gene Expression
Regulation Of Neuron Maturation
Negative Regulation Of Glycogen (starch) Synthase Activity
Positive Regulation Of Cellular Biosynthetic Process
Protein Localization To Microtubule
Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway
Negative Regulation Of Dendrite Morphogenesis
Negative Regulation Of NFAT Protein Import Into Nucleus
Negative Regulation Of Phosphorylation
ER Overload Response
Negative Regulation Of Cardiac Muscle Hypertrophy
Multicellular Organismal Development
Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of Glycogen Biosynthetic Process
Negative Regulation Of Muscle Hypertrophy
Regulation Of Glycogen (starch) Synthase Activity
Anatomical Structure Development
Regulation Of Nitrogen Compound Metabolic Process
Establishment Of Localization In Cell
Positive Regulation Of Protein Export From Nucleus
Regulation Of Type B Pancreatic Cell Development
Positive Regulation Of Peptidyl-threonine Phosphorylation
Negative Regulation Of Dendrite Development
Developmental Process
Regulation Of DNA Methylation
Myoblast Fusion
Protein Localization To Cytoskeleton
Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway
Cellular Localization
Regulation Of Gene Expression By Genetic Imprinting
Cell Cycle
Microtubule-based Process
Organelle Organization
Cell Cycle Process
Mitotic Cell Cycle
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II
Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II
Microtubule-based Movement
Microtubule-based Transport
Regulation Of Cell Cycle
Cytoskeleton-dependent Intracellular Transport
Minus-end-directed Organelle Transport Along Microtubule
Movement Of Cell Or Subcellular Component
Mitotic Cell Cycle Process
Regulation Of Microtubule-based Process
Antigen Processing And Presentation
Organelle Transport Along Microtubule
Immune System Process
Microtubule Cytoskeleton Organization
G2/M Transition Of Mitotic Cell Cycle
Regulation Of Cellular Component Organization
Antigen Processing And Presentation Of Peptide Antigen
Intracellular Transport
Execution Phase Of Apoptosis
Cellular Protein Localization
Cytoskeleton Organization
Mitotic Cell Cycle Phase Transition
Cell Cycle Phase Transition
Protein Localization
Cellular Localization
Microtubule Anchoring At Microtubule Organizing Center
Neurotrophin TRK Receptor Signaling Pathway
Regulation Of Metabolic Process
Neurotrophin Signaling Pathway
Regulation Of Organelle Organization
Establishment Of Localization In Cell
Protein Localization To Cytoskeleton
Cell Division
Generation Of Neurons
Regulation Of Generation Of Precursor Metabolites And Energy
Positive Regulation Of Cilium Assembly
Organelle Assembly
Neurogenesis
Mitotic Nuclear Division
Anatomical Structure Development
Regulation Of Cell Projection Organization
Nervous System Development
Enzyme Linked Receptor Protein Signaling Pathway
Regulation Of Cell Cycle Process
Tagcloud
?
als2
c147r
causative
chmp2b
dao
diagnose
f21c
faces
fig4
g148d
g59r
got
haloplex
optn
pedigree
pfn1
probands
sanger
segregate
setx
sigmar1
sod1
spg11
sqstm1
synonymous
tardbp
ubqln2
vapb
vcp
Tagcloud (Difference)
?
als2
c147r
causative
chmp2b
dao
diagnose
f21c
faces
fig4
g148d
g59r
got
haloplex
optn
pedigree
pfn1
probands
sanger
segregate
setx
sigmar1
sod1
spg11
sqstm1
synonymous
tardbp
ubqln2
vapb
vcp
Tagcloud (Intersection)
?