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BIRC8 and UBE2G2
Number of citations of the paper that reports this interaction (PMID
19690564
)
33
Data Source:
BioGRID
(two hybrid)
BIRC8
UBE2G2
Gene Name
baculoviral IAP repeat containing 8
ubiquitin-conjugating enzyme E2G 2
Image
Gene Ontology Annotations
Cellular Component
Nucleus
Cytoplasm
Cytosol
Spindle Microtubule
Perinuclear Region Of Cytoplasm
Endoplasmic Reticulum
Cytosol
Molecular Function
Protease Binding
Ubiquitin-protein Transferase Activity
Zinc Ion Binding
Cysteine-type Endopeptidase Inhibitor Activity Involved In Apoptotic Process
Scaffold Protein Binding
Ubiquitin-protein Transferase Activity
Protein Binding
ATP Binding
Ligase Activity
Ubiquitin-like Protein Transferase Activity
Ubiquitin Protein Ligase Binding
Identical Protein Binding
Ubiquitin Protein Ligase Activity
Ubiquitin Conjugating Enzyme Activity
Biological Process
Protein Ubiquitination
Negative Regulation Of Apoptotic Process
Negative Regulation Of Neuron Apoptotic Process
Neuron Apoptotic Process
Positive Regulation Of Canonical Wnt Signaling Pathway
Mitotic Spindle Assembly
Inhibition Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Ubiquitin-dependent Protein Catabolic Process
Protein N-linked Glycosylation Via Asparagine
ER-associated Ubiquitin-dependent Protein Catabolic Process
Cellular Protein Catabolic Process
Protein K48-linked Ubiquitination
Pathways
Antigen processing: Ubiquitination & Proteasome degradation
Class I MHC mediated antigen processing & presentation
Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions
12 interactors:
CASP9
MAGED1
UBE2D1
UBE2D2
UBE2D3
UBE2D4
UBE2E1
UBE2G2
UBE2K
UBE2N
UBE2V1
UBE2W
37 interactors:
AMFR
ARL14
BIRC8
CBL
CNNM3
CPOX
CUL9
FARP2
HBS1L
HERPUD1
KDM2A
KIAA0368
MDM2
MGRN1
MLLT6
MUL1
NDUFS4
PARK2
POLR3F
RBX1
RFFL
RNF111
RNF146
RNF157
RNF168
RNF26
RNF5
TMEM45B
TRIM3
TRIM43
UBA1
UBA6
UBC
UBE2J2
UBE3A
VAMP8
ZNRF4
Entrez ID
112401
7327
HPRD ID
12525
04387
Ensembl ID
ENSG00000163098
ENSG00000184787
Uniprot IDs
Q6PIA0
Q96P09
P60604
PDB IDs
1XB0
1XB1
2CYX
2KLY
2LXP
3H8K
4LAD
Enriched GO Terms of Interacting Partners
?
Protein Polyubiquitination
Protein K48-linked Ubiquitination
Protein Ubiquitination
Protein Modification By Small Protein Conjugation
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Protein Catabolic Process
Toll-like Receptor 4 Signaling Pathway
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Cellular Macromolecule Catabolic Process
Proteasomal Protein Catabolic Process
Toll-like Receptor Signaling Pathway
Proteolysis
Pattern Recognition Receptor Signaling Pathway
Innate Immune Response-activating Signal Transduction
Activation Of Innate Immune Response
Positive Regulation Of Innate Immune Response
Immune Response-regulating Signaling Pathway
Regulation Of Innate Immune Response
Cellular Response To Stress
Cellular Protein Modification Process
Protein K11-linked Ubiquitination
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Catabolic Process
Protein K63-linked Ubiquitination
Protein Metabolic Process
Protein Monoubiquitination
Innate Immune Response
Regulation Of Immune Response
Cellular Protein Metabolic Process
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress
Regulation Of DNA-templated Transcription In Response To Stress
TRIF-dependent Toll-like Receptor Signaling Pathway
MyD88-independent Toll-like Receptor Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
Positive Regulation Of Ubiquitin-protein Transferase Activity
Positive Regulation Of Ligase Activity
Positive Regulation Of Immune Response
Cellular Response To Organic Substance
Regulation Of Ubiquitin-protein Transferase Activity
Cellular Response To Hypoxia
Cellular Response To Decreased Oxygen Levels
Immune Response
Regulation Of Immune System Process
Defense Response
Cellular Response To Oxygen Levels
Regulation Of Response To DNA Damage Stimulus
Cellular Response To DNA Damage Stimulus
Protein Ubiquitination
Protein Modification By Small Protein Conjugation
Modification-dependent Protein Catabolic Process
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Protein Catabolic Process
Ubiquitin-dependent Protein Catabolic Process
Cellular Macromolecule Catabolic Process
Protein Polyubiquitination
Catabolic Process
Proteolysis
Cellular Protein Metabolic Process
Cellular Protein Modification Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Proteasomal Protein Catabolic Process
Protein K48-linked Ubiquitination
Protein Metabolic Process
Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
ER-associated Ubiquitin-dependent Protein Catabolic Process
Protein Monoubiquitination
Cellular Response To Stress
Cellular Metabolic Process
Regulation Of Proteolysis
Regulation Of Signaling
Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Negative Regulation Of Cysteine-type Endopeptidase Activity
Regulation Of Signal Transduction
Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Regulation Of Protein Ubiquitination
Regulation Of Cysteine-type Endopeptidase Activity
Negative Regulation Of Signal Transduction
Protein K63-linked Ubiquitination
Cellular Response To Topologically Incorrect Protein
Negative Regulation Of Mitochondrial Fusion
Negative Regulation Of Intracellular Signal Transduction
Negative Regulation Of Signaling
Regulation Of Mitochondrial Fusion
Protein Autoubiquitination
Response To Stimulus
Response To Unfolded Protein
Regulation Of Protein Stability
Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process
Positive Regulation Of Proteolysis
Positive Regulation Of Cellular Protein Catabolic Process
Cellular Response To Stimulus
Response To Organic Substance
Positive Regulation Of Mitochondrial Fission
Regulation Of Intracellular Signal Transduction
Response To Stress
Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Tagcloud
?
alters
assembly
attack
bond
catalyzes
chain
chains
cooperative
cooperatively
correct
cue
distal
donor
drive
e3
elusive
g2br
gp78
helps
lys48
monoubiquitin
orientation
polyubiquitin
preassembled
preferential
thioester
transferring
ubiquitin
Tagcloud (Difference)
?
alters
assembly
attack
bond
catalyzes
chain
chains
cooperative
cooperatively
correct
cue
distal
donor
drive
e3
elusive
g2br
gp78
helps
lys48
monoubiquitin
orientation
polyubiquitin
preassembled
preferential
thioester
transferring
ubiquitin
Tagcloud (Intersection)
?