BIRC8

Description		baculoviral IAP repeat containing 8
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm
	Molecular Function	Ubiquitin-protein Transferase Activity Cysteine-type Endopeptidase Inhibitor Activity Zinc Ion Binding Cysteine-type Endopeptidase Inhibitor Activity Involved In Apoptotic Process Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Apoptotic Process Negative Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of Protein Ubiquitination Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Positive Regulation Of JNK Cascade Regulation Of Cell Cycle Positive Regulation Of Canonical Wnt Signaling Pathway
Pathways
Drugs
Diseases
GWAS
Interacting Genes		14 interacting genes: CASP9 FAM107A MAGED1 TNPO2 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2G2 UBE2K UBE2N UBE2V1 UBE2W
Entrez ID		112401
HPRD ID		12525
Ensembl ID		ENSG00000293247
Uniprot IDs
PDB IDs
Enriched GO Terms of Interacting Partners?		Ubiquitin Conjugating Enzyme Activity Protein Polyubiquitination Ubiquitin-protein Transferase Activity Protein K48-linked Ubiquitination Protein Ubiquitination Protein Modification By Small Protein Conjugation Post-translational Protein Modification Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Protein Catabolic Process Proteolysis Macromolecule Catabolic Process Protein Modification Process Protein Monoubiquitination ATP Binding Positive Regulation Of Protein Polyubiquitination Protein Metabolic Process Nucleotide Binding Transferase Activity Positive Regulation Of Protein Ubiquitination Regulation Of Protein Polyubiquitination UBC13-MMS2 Complex Catabolic Process Positive Regulation Of Post-translational Protein Modification Ubiquitin Conjugating Enzyme Complex Protein K11-linked Ubiquitination Positive Regulation Of Protein Modification Process Regulation Of Protein Ubiquitination Protein-containing Complex Positive Regulation Of Protein K63-linked Ubiquitination TORC1 Signaling Negative Regulation Of TORC1 Signaling Nucleus Proteasomal Protein Catabolic Process Protein K63-linked Ubiquitination Regulation Of Post-translational Protein Modification TOR Signaling Cellular Response To Nutrient Levels Negative Regulation Of TOR Signaling Regulation Of Protein K63-linked Ubiquitination Regulation Of TORC1 Signaling Ubiquitin Ligase Complex Protein Catabolic Process Regulation Of Protein Modification Process Macromolecule Metabolic Process Cellular Response To Interferon-beta Protein K6-linked Ubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of TOR Signaling DNA Damage Response
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