ETV3

Name	ETS variant transcription factor 3
Structure	No pdb structure
Interactors	3 interactors: APP DDX20 NSD3
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Transcription Repressor Complex RNA Polymerase II Transcription Repressor Complex
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity DEAD/H-box RNA Helicase Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Cell Population Proliferation Cell Differentiation Cellular Response To Granulocyte Macrophage Colony-stimulating Factor Stimulus
GWAS	Attention deficit hyperactivity disorder and conduct disorder ( 18951430 ) Hepatitis B virus-related hepatocellular carcinoma vs hepatitis B virus-related decompensated cirrhosis ( 33736632 ) Systemic lupus erythematosus ( 33272962 )
Entrez ID	2117
HPRD ID	01282
Ensembl ID	ENSG00000117036
Uniprot IDs	P41162
PDB IDs	Not available
GO Terms Enriched among Interactors ?	Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Response To Calcium Ion Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Histone H3K4 Dimethyltransferase Activity Histone H3K27 Trimethyltransferase Activity Histone H3K27 Dimethyltransferase Activity Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Cellular Response To Norepinephrine Stimulus Growth Factor Receptor Binding Main Axon Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Histone H3K27 Methyltransferase Activity Axon Choice Point Recognition Heparan Sulfate Binding Signaling Receptor Activator Activity RNA Polymerase II Transcription Repressor Complex Peptidase Activator Activity Cellular Response To Manganese Ion Negative Regulation Of Blood Circulation Regulation Of Superoxide Anion Generation Collateral Sprouting Positive Regulation Of Apoptotic Process Heparan Sulfate Proteoglycan Binding Acetylcholine Receptor Binding Golgi-associated Vesicle Insulin Receptor Binding Apolipoprotein Binding