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AKAP11 and PPP1CC
Number of citations of the paper that reports this interaction (PubMedID
10209101
)
0
Data Source:
HPRD
(in vitro)
AKAP11
PPP1CC
Description
A-kinase anchoring protein 11
protein phosphatase 1 catalytic subunit gamma
Image
No pdb structure
GO Annotations
Cellular Component
Nucleolus
Cytoplasm
Centrosome
Cytosol
Cytoskeleton
Plasma Membrane
Chromosome, Centromeric Region
Kinetochore
Chromosome, Telomeric Region
Nucleus
Nucleoplasm
Chromosome
Nucleolus
Cytoplasm
Mitochondrion
Mitochondrial Outer Membrane
Microtubule Organizing Center
Cytosol
Cytoskeleton
Focal Adhesion
Nuclear Speck
Midbody
Cleavage Furrow
Protein-containing Complex
Dendritic Spine
PTW/PP1 Phosphatase Complex
Presynapse
Postsynapse
Glutamatergic Synapse
Molecular Function
Protein Binding
Protein Phosphatase 1 Binding
Protein Kinase A Regulatory Subunit Binding
Protein Kinase A Binding
RNA Binding
Phosphoprotein Phosphatase Activity
Protein Serine/threonine Phosphatase Activity
Protein Binding
Lamin Binding
Protein Phosphatase 1 Binding
Hydrolase Activity
Phosphatase Activity
Protein Kinase Binding
Protein Phosphatase Binding
Protein Domain Specific Binding
Protein-containing Complex Binding
Metal Ion Binding
Biological Process
Renal Water Homeostasis
Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway
Intracellular Protein Localization
Cortical Actin Cytoskeleton Organization
Intracellular Signal Transduction
Protein Localization To Endosome
Mitotic Sister Chromatid Segregation
MAPK Cascade
Blastocyst Development
Glycogen Metabolic Process
Protein Dephosphorylation
Spermatogenesis
Neuron Differentiation
Circadian Regulation Of Gene Expression
Regulation Of Circadian Rhythm
Entrainment Of Circadian Clock By Photoperiod
Regulation Of Nucleocytoplasmic Transport
Rhythmic Process
Cell Division
Positive Regulation Of Glial Cell Proliferation
Pathways
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Triglyceride catabolism
Downregulation of TGF-beta receptor signaling
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
RHO GTPases Activate Formins
RAF activation
Mitotic Prometaphase
EML4 and NUDC in mitotic spindle formation
SHOC2 M1731 mutant abolishes MRAS complex function
Gain-of-function MRAS complexes activate RAF signaling
Maturation of hRSV A proteins
Phosphorylation and nuclear translocation of the CRY:PER:kinase complex
Drugs
9,10-Deepithio-9,10-Didehydroacanthifolicin
Calyculin A
Motuporin
Diseases
GWAS
Allergic disease (asthma, hay fever and/or eczema) (age of onset) (
32603359
)
Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis) (
32603359
)
Allergic rhinitis (
30013184
)
Asthma (childhood onset) (
30929738
)
Bone mineral density (
24249740
)
Bone mineral density (spine) (
19801982
)
Crohn's disease (
28067908
)
Hepcidin levels (
27846281
)
Inflammatory bowel disease (
28067908
)
Lumbar spine bone mineral density (
22504420
29499414
)
Lumbar spine bone mineral density (integral) (
27476799
)
Lumbar spine bone mineral density (trabecular) (
27476799
)
Medication use (drugs affecting bone structure and mineralization) (
31015401
)
Medication use (thyroid preparations) (
31015401
)
Neutrophil count (
32888494
)
Neutrophil percentage of white cells (
32888494
)
Serum alkaline phosphatase levels (
33339817
33547301
)
Type 1 diabetes (
34012112
34127860
)
Heart rate (
23583979
)
Interacting Genes
8 interacting genes:
GSK3A
GSK3B
PPP1CA
PPP1CC
PRKAR1A
PRKAR2A
PRKAR2B
WEE2-AS1
128 interacting genes:
ABT1
ACAD8
AKAP11
ANKRD42
APIP
APP
ASH2L
AURKA
B4GAT1
BMPR2
BTBD10
C14orf180
C1QA
C9orf50
CEP126
CLMN
CLOCK
CLTC
CNST
COPS5
CSNK1A1
CSNK1E
CSNK2B
CSRNP2
CTSL
CYFIP1
DACT1
DEAF1
DELEC1
DYNLT4
DYRK4
EIF2AK2
ELP4
ENKD1
FBXW11
FTL
FXYD6
GLB1L
GOLGA7
GSTZ1
HCFC1
HDAC6
HMGN1
IFTAP
IL3RA
INSYN1
IRAK1
JAK2
KCTD20
KDM4D
KRCC1
LMTK2
MAP4K4
MAPT
MYO16
NAPEPLD
NEK2
NMT2
NONO
NRBP1
NUAK1
PHACTR4
PHC1
PIAS1
POLR1F
PPP1R11
PPP1R15B
PPP1R16A
PPP1R18
PPP1R2
PPP1R2B
PPP1R2C
PPP1R35
PPP1R3A
PPP1R3C
PPP1R3D
PPP1R7
PPP1R8
PPP1R9A
PPP2R5C
PRR16
RAF1
RB1
RIF1
RNF19B
RORC
RPL7
RPRD2
RRM1
RRP1B
SAXO4
SDR39U1
SFRP1
SGCE
SH3RF2
SHANK3
SMARCB1
SMG6
SPATC1L
SPOCD1
STAM
STARD9
SUMO2
TACC2
TBC1D19
TEFM
TEX36
TLX1
TLX3
TMEM120A
TNS1
TOPBP1
TOR1AIP1
TP53
TP53BP2
TPRN
TRA2A
VCP
VSTM4
WBP11
YLPM1
YWHAZ
ZDBF2
ZFYVE9
ZNF24
ZNF318
ZNF629
ZNF667
Entrez ID
11215
5501
HPRD ID
05261
08911
Ensembl ID
ENSG00000023516
ENSG00000186298
Uniprot IDs
Q9UKA4
P36873
PDB IDs
1IT6
1JK7
1U32
2BCD
2BDX
4UT2
4UT3
5INB
5J28
7SD0
8B5R
Enriched GO Terms of Interacting Partners
?
Protein Kinase A Catalytic Subunit Binding
CAMP-dependent Protein Kinase Regulator Activity
CAMP-dependent Protein Kinase Complex
CAMP-dependent Protein Kinase Inhibitor Activity
Glycogen Metabolic Process
Energy Reserve Metabolic Process
Polysaccharide Metabolic Process
Postsynapse
CAMP Binding
Negative Regulation Of Type B Pancreatic Cell Development
Negative Regulation Of Glycogen (starch) Synthase Activity
Negative Regulation Of CAMP/PKA Signal Transduction
Regulation Of Glycogen Biosynthetic Process
Regulation Of Glycogen Metabolic Process
Ciliary Base
Regulation Of Glycogen (starch) Synthase Activity
Regulation Of CAMP/PKA Signal Transduction
Energy Derivation By Oxidation Of Organic Compounds
Beta-arrestin-dependent Dopamine Receptor Signaling Pathway
Protein Domain Specific Binding
Glutamatergic Synapse
Cellular Response To Interleukin-3
PTW/PP1 Phosphatase Complex
Rhythmic Process
Regulation Of Type B Pancreatic Cell Development
Negative Regulation Of Glycogen Biosynthetic Process
Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Ubiquitin Protein Ligase Binding
Generation Of Precursor Metabolites And Energy
Nucleotide-activated Protein Kinase Complex
Beta-catenin Destruction Complex
Negative Regulation Of Intracellular Signal Transduction
Regulation Of Circadian Rhythm
Carbohydrate Metabolic Process
Regulation Of Generation Of Precursor Metabolites And Energy
Circadian Rhythm
Tau-protein Kinase Activity
Dendritic Spine
Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway
Entrainment Of Circadian Clock By Photoperiod
Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Protein Phosphatase 1 Binding
Viral Protein Processing
Positive Regulation Of Mitochondrial Membrane Permeability
Photoperiodism
Entrainment Of Circadian Clock
Positive Regulation Of Membrane Permeability
Plasma Membrane Raft
Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Presynapse
Protein Phosphatase 1 Binding
Protein Phosphatase Inhibitor Activity
Phosphatase Binding
Protein Phosphatase Regulator Activity
Protein Serine/threonine Kinase Activity
Protein Phosphorylation
Protein Serine/threonine Phosphatase Inhibitor Activity
Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Protein Phosphatase Type 1 Complex
Phosphorylation
Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Viral Process
Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Proteolysis
Positive Regulation Of Protein Catabolic Process
Regulation Of Proteolysis
Macromolecule Metabolic Process
Nucleoplasm
Protein Kinase Activity
Positive Regulation Of Proteasomal Protein Catabolic Process
Inclusion Body Assembly
Glycogen Binding
Disordered Domain Specific Binding
Regulation Of Ubiquitin-dependent Protein Catabolic Process
Microtubule Cytoskeleton Organization Involved In Mitosis
Regulation Of Generation Of Precursor Metabolites And Energy
Microglial Cell Activation
Protein Serine Kinase Activity
Positive Regulation Of Proteolysis Involved In Protein Catabolic Process
Protein Phosphatase Binding
Nucleus
Glycogen Metabolic Process
Leukocyte Activation Involved In Inflammatory Response
Chromatin Remodeling
Actin Binding
Regulation Of Protein Metabolic Process
Regulation Of Primary Metabolic Process
Chromatin Organization
Protein Modification Process
Regulation Of Proteasomal Protein Catabolic Process
PML Body
Type II Interferon-mediated Signaling Pathway
Germ Cell Nucleus
Polysaccharide Metabolic Process
Regulation Of Circadian Rhythm
Energy Reserve Metabolic Process
Epigenetic Regulation Of Gene Expression
DNA Damage Response
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Astrocyte Activation
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Tagcloud (Intersection)
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