RAB3B and RIMS2

Number of citations of the paper that reports this interaction (PMID 12578829)
33

Data Source:
HPRD (in vitro)

		RAB3B	RIMS2
Gene Name		RAB3B, member RAS oncogene family	regulating synaptic membrane exocytosis 2
Image
Gene Ontology Annotations	Cellular Component	Cytoplasm Endosome Cytosol Plasma Membrane Synaptic Vesicle Secretory Granule Membrane Vesicle Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome	Cell Junction Presynaptic Membrane Presynaptic Active Zone Extracellular Vesicular Exosome
	Molecular Function	GTPase Activity Protein Binding GTP Binding GDP Binding Myosin V Binding	Protein Binding Rab GTPase Binding Ion Channel Binding Metal Ion Binding
	Biological Process	Intracellular Protein Transport Vesicle Docking Involved In Exocytosis Protein Secretion Synaptic Vesicle Exocytosis Regulation Of Exocytosis Peptidyl-cysteine Methylation Antigen Processing And Presentation Rab Protein Signal Transduction Positive Regulation Of Dopamine Uptake Involved In Synaptic Transmission Protein Localization To Plasma Membrane Regulation Of Vesicle Size	Intracellular Protein Transport Positive Regulation Of Gene Expression Calcium Ion-dependent Exocytosis Regulation Of Exocytosis CAMP-mediated Signaling Insulin Secretion Regulation Of Membrane Potential Calcium Ion-dependent Exocytosis Of Neurotransmitter Positive Regulation Of Inhibitory Postsynaptic Membrane Potential Positive Regulation Of Excitatory Postsynaptic Membrane Potential
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		13 interactors: ACVR1 CALM1 CALM2 CALM3 CHM GDI1 PIGR RIMS2 RPH3A RPH3AL SMAD1 SMAD4 TGFBR1	12 interactors: ABCA1 CACNA1S RAB27A RAB3A RAB3B RAB3C RAB3D RAB8A RABAC1 RAPGEF4 RPH3AL YWHAH
Entrez ID		5865	9699
HPRD ID		01540	09436
Ensembl ID		ENSG00000169213
Uniprot IDs		P20337	Q9UQ26
PDB IDs		3DZ8	1V27 1WFG
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Regulation Of High Voltage-gated Calcium Channel Activity Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Cellular Response To Growth Factor Stimulus Response To Growth Factor Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Regulation Of Cellular Localization Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Detection Of Calcium Ion Regulation Of Cell Communication By Electrical Coupling Regulation Of Intracellular Transport Positive Regulation Of Phosphoprotein Phosphatase Activity Intracellular Signal Transduction Positive Regulation Of Peptidyl-threonine Phosphorylation Positive Regulation Of Protein Autophosphorylation Midbrain Development Positive Regulation Of Nitric-oxide Synthase Activity Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Negative Regulation Of Calcium Ion Transmembrane Transporter Activity Glycogen Catabolic Process Negative Regulation Of Peptidyl-threonine Phosphorylation Regulation Of Voltage-gated Calcium Channel Activity Positive Regulation Of Protein Dephosphorylation Negative Regulation Of Cation Channel Activity Polysaccharide Catabolic Process Positive Regulation Of Monooxygenase Activity Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Positive Regulation Of Calcium Ion Transmembrane Transporter Activity Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Rhodopsin Mediated Signaling Pathway Response To Calcium Ion Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Activation Of Adenylate Cyclase Activity Nitric Oxide Metabolic Process Regulation Of Protein Autophosphorylation Transforming Growth Factor Beta Receptor Signaling Pathway Reactive Nitrogen Species Metabolic Process Rhodopsin Mediated Signaling Pathway Cellular Carbohydrate Catabolic Process Exocytosis Positive Regulation Of Phosphatase Activity Response To Corticosterone Positive Regulation Of Metabolic Process Positive Regulation Of Cation Channel Activity Response To Amphetamine Second-messenger-mediated Signaling Positive Regulation Of Adenylate Cyclase Activity Regulation Of Phosphoprotein Phosphatase Activity Positive Regulation Of Protein Phosphorylation	Protein Secretion Regulation Of Exocytosis Secretion By Cell Rab Protein Signal Transduction Vesicle Docking Involved In Exocytosis Exocytosis Secretion Regulation Of Vesicle-mediated Transport Vesicle Docking Membrane Docking Synaptic Vesicle Transport Protein Transport Establishment Of Protein Localization Synaptic Vesicle Exocytosis Regulation Of Cellular Localization Regulation Of Secretion Protein Localization Establishment Of Vesicle Localization Vesicle Localization Establishment Of Localization In Cell Ras Protein Signal Transduction Vesicle-mediated Transport Intracellular Protein Transport Neurotransmitter Secretion Intracellular Transport Cellular Localization Small GTPase Mediated Signal Transduction Establishment Of Organelle Localization Regulation Of Neurotransmitter Levels Neurotransmitter Transport Positive Regulation Of Transport Organelle Localization Cellular Protein Localization Cell-cell Signaling Transport Positive Regulation Of Regulated Secretory Pathway Synaptic Transmission Intracellular Signal Transduction Peptidyl-cysteine Methylation Regulation Of Regulated Secretory Pathway Positive Regulation Of Exocytosis Regulation Of Synaptic Transmission Response To Stimulus Positive Regulation Of Secretion Endomembrane System Organization Signal Transduction Regulation Of Synaptic Plasticity Signaling Cell Communication Vesicle Organization
Tagcloud ?		1h basilar camk2a camk2b capn1 capn2 cisplatin cochlea deacetylases ganglion hair hdacs immunocytochemistry label neurofilament neurotransmitter newborn organotypic ototoxicity panther phalloidin rhodamine sgns snap25 spiral tnfrsf1a trichostatin tsa vglut1
Tagcloud (Difference) ?		1h basilar camk2a camk2b capn1 capn2 cisplatin cochlea deacetylases ganglion hair hdacs immunocytochemistry label neurofilament neurotransmitter newborn organotypic ototoxicity panther phalloidin rhodamine sgns snap25 spiral tnfrsf1a trichostatin tsa vglut1
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