CEP250 and ATF7IP

Number of citations of the paper that reports this interaction (PMID 15231748)
65

Data Source:
HPRD (two hybrid)

		CEP250	ATF7IP
Gene Name		centrosomal protein 250kDa	activating transcription factor 7 interacting protein
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Centrosome Centriole Microtubule Organizing Center Cytosol Cilium Spindle Pole Centrosome Protein Complex Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome	Nucleus Nucleoplasm Transcription Factor Complex Cytoplasm
	Molecular Function	Protein Binding Protein C-terminus Binding Protein Kinase Binding Protein Domain Specific Binding	Transcription Corepressor Activity Protein Binding ATPase Activity
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Organelle Organization Protein Localization Centriole-centriole Cohesion Regulation Of Centriole-centriole Cohesion Protein Localization To Organelle	Negative Regulation Of Transcription From RNA Polymerase II Promoter DNA Methylation Chromatin Organization Transcription, DNA-templated Viral Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Regulation Of RNA Polymerase II Transcriptional Preinitiation Complex Assembly
Pathways		Organelle biogenesis and maintenance Loss of proteins required for interphase microtubule organizationÂ from the centrosome Loss of Nlp from mitotic centrosomes G2/M Transition Assembly of the primary cilium Centrosome maturation Regulation of PLK1 Activity at G2/M Transition Mitotic G2-G2/M phases Anchoring of the basal body to the plasma membrane Recruitment of mitotic centrosome proteins and complexes Cell Cycle, Mitotic	Chromatin modifying enzymes Chromatin organization PKMTs methylate histone lysines
Drugs
Diseases
GWAS		Height ( 18391951) Ulcerative colitis ( 23128233)	Prostate-specific antigen levels ( 23359319) Testicular germ cell cancer ( 20543847) Testicular germ cell tumor ( 23666240)
Protein-Protein Interactions		6 interactors: APP ATF7IP KAT2B NEK2 PLEKHA5 YWHAG	68 interactors: A2M ACTB ACTG1 AP1B1 CADM1 CEP250 COL4A2 CREB1 CSPG4 DISC1 DMTF1 DNM2 EPG5 FLNB FLT4 GMEB1 GTF2E2 GTF2F1 GTF2H1 HEYL HLA-B HSPG2 KIF13A KRT7 LAMA4 LAMA5 LAMC1 LUC7L2 MACF1 MBD1 MCAM MED4 MRI1 NOMO1 NPR1 PAPPA PAPPA2 PCDH1 PEX6 PIAS3 PKD1 PLEKHB2 POLR2C POLR2D POLR2G PRSS8 PSG3 QRICH1 RPS3A RRBP1 SENP3 SETDB1 SLC12A4 SMAD4 SP1 SPTBN1 SREBF2 STBD1 STRN SUMO3 SUSD1 SVEP1 TRIP12 TTC3 UBE2I ZBTB6 ZNF350 ZNF518A
Entrez ID		11190	55729
HPRD ID		09877	09811
Ensembl ID		ENSG00000126001	ENSG00000171681
Uniprot IDs		Q9BV73	B3KNI7 B3KQF8 F5GX74 G3V1U0 Q6VMQ6
PDB IDs			2RPQ
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Centriole-centriole Cohesion G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Protein Serine/threonine Kinase Activity Histone H3-K9 Acetylation Regulation Of Protein ADP-ribosylation Synaptic Growth At Neuromuscular Junction Notch Signaling Pathway Regulation Of Protein Kinase Activity Negative Regulation Of Catalytic Activity Regulation Of Kinase Activity Collateral Sprouting In Absence Of Injury Regulation Of Centriole-centriole Cohesion N-terminal Peptidyl-lysine Acetylation Negative Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Protein Metabolic Process Regulation Of Cell Cycle Cellular Response To Insulin Stimulus Regulation Of Mitotic Centrosome Separation Collateral Sprouting Axon Midline Choice Point Recognition Negative Regulation Of Protein Kinase Activity Negative Regulation Of Kinase Activity Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Chromosome Organization Cell Cycle Process Axon Choice Point Recognition Positive Regulation Of Gluconeogenesis By Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Protein Phosphorylation Regulation Of Binding Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Regulation Of RNA Polymerase II Transcriptional Preinitiation Complex Assembly Regulation Of Cellular Ketone Metabolic Process By Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Gluconeogenesis By Regulation Of Transcription From RNA Polymerase II Promoter Response To Insulin Neuron Remodeling Negative Regulation Of Transferase Activity Cellular Response To Peptide Hormone Stimulus Regulation Of Protein Glycosylation Negative Regulation Of Protein Phosphorylation Cellular Response To Peptide Regulation Of Phosphorylation N-terminal Protein Amino Acid Acetylation Positive Regulation Of Transcription, DNA-templated Cell Cycle Organelle Organization Centrosome Separation Negative Regulation Of Phosphorylation Regulation Of Phosphorus Metabolic Process	Transcription Initiation From RNA Polymerase II Promoter Viral Process Positive Regulation Of Viral Transcription Cell Differentiation DNA-templated Transcription, Initiation Transcription Elongation From RNA Polymerase II Promoter 7-methylguanosine MRNA Capping Regulation Of Viral Transcription 7-methylguanosine RNA Capping Positive Regulation Of Viral Process Transcription From RNA Polymerase II Promoter DNA-templated Transcription, Elongation RNA Biosynthetic Process Developmental Process Transcription, DNA-templated Anatomical Structure Development Regulation Of Viral Process Post-Golgi Vesicle-mediated Transport Macromolecule Biosynthetic Process Transcription-coupled Nucleotide-excision Repair Gene Expression RNA Metabolic Process Extracellular Matrix Disassembly Cellular Macromolecule Biosynthetic Process Anatomical Structure Morphogenesis System Development Cell Junction Assembly Cardiovascular System Development Stem Cell Differentiation Anatomical Structure Formation Involved In Morphogenesis Biosynthetic Process Nervous System Development Neurogenesis Angiogenesis Positive Regulation Of Cellular Metabolic Process Nitrogen Compound Metabolic Process Golgi To Plasma Membrane Protein Transport Somatic Stem Cell Maintenance Protein Sumoylation Positive Regulation Of Gene Expression Multicellular Organismal Development Generation Of Neurons Stem Cell Development Blood Vessel Development Establishment Of Protein Localization To Plasma Membrane Positive Regulation Of Cellular Biosynthetic Process Nucleobase-containing Compound Metabolic Process Axon Guidance Golgi Vesicle Transport Vasculature Development
Tagcloud ?			acgh adherent cce cd15 cd29 cd44 cd90 continuously csmd1 cultivation cytokeratins cytometric devastating doubling explant grin2b hypercalcemia hypercalcemic karyotype lentiviral oligo outgrowth paralleled park2 proliferating sccoht similarities subpopulations vimentin
Tagcloud (Difference) ?			acgh adherent cce cd15 cd29 cd44 cd90 continuously csmd1 cultivation cytokeratins cytometric devastating doubling explant grin2b hypercalcemia hypercalcemic karyotype lentiviral oligo outgrowth paralleled park2 proliferating sccoht similarities subpopulations vimentin
Tagcloud (Intersection) ?