BTN2A1 and CTXN3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		BTN2A1	CTXN3
Description		butyrophilin subfamily 2 member A1	cortexin 3
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane External Side Of Plasma Membrane Membrane	Membrane
	Molecular Function	Signaling Receptor Binding Protein Binding	Protein Binding
	Biological Process	Regulation Of Cytokine Production Lipid Metabolic Process T Cell Receptor Signaling Pathway
Pathways		Butyrophilin (BTN) family interactions
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Brain morphology (MOSTest) ( 32665545) Chronic obstructive pulmonary disease ( 33909500) Cutaneous mastocytosis ( 32752121) Fish- and plant-related diet ( 32066663) Gastroesophageal reflux disease ( 31527586 34187846) General cognitive ability ( 29844566) Intelligence (MTAG) ( 29326435) Lung cancer ( 31577861) Lung cancer in ever smokers ( 28604730) Refractive error ( 32231278) Subcortical volume (MOSTest) ( 32665545) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Brain imaging in schizophrenia (dorsolateral prefrontal cortex interaction) ( 19023125) Plasma amyloid beta peptide concentrations (ABx-42) ( 24535457)
Interacting Genes		6 interacting genes: CLDN19 CTXN3 MAL NSG1 PLPP6 STRIT1	59 interacting genes: ADGRG3 AQP6 AQP9 ATP1B3 BIK BTN2A1 CD300E CD53 CD79A CERS4 CLDN14 CLEC17A CLEC7A CLRN1 COQ9 CPLX4 CREB3L1 CTLA4 EDA ERGIC3 FAM209A FFAR3 FUT7 GJA8 GJB1 GJB5 GPR152 GPR42 GPR61 IFNLR1 KASH5 KIR3DL3 KLRC1 LAPTM4B LDLRAD1 LHFPL5 LSMEM2 MFF MGST2 MTIF3 NCAPH2 OPRD1 OPRM1 PACC1 PLPP5 PVR SCN3B SLC10A2 SPACA1 STOM TLCD4 TM4SF19 TMEM106C TMEM167B TMEM179B TMEM31 TMPRSS2 TMX2 TSPAN12
Entrez ID		11120	613212
HPRD ID		12544	18888
Ensembl ID		ENSG00000112763	ENSG00000205279
Uniprot IDs		Q7KYR7	Q4LDR2
PDB IDs		8DFW 8DFX 8DFY 8JYC 8JYE 8VC7
Enriched GO Terms of Interacting Partners?		Schmidt-Lanterman Incisure Protein Insertion Into Plasma Membrane Hinge Region Between Urothelial Plaques Of Apical Plasma Membrane Postsynaptic Neurotransmitter Receptor Cycle Neurotransmitter Receptor Cycle Isoprenoid Diphosphate Phosphatase Activity Farnesyl Diphosphate Catabolic Process Geranylgeranyl Diphosphate Catabolic Process Spontaneous Synaptic Transmission Mesaxon Positive Regulation Of Calcium Ion Import Into Sarcoplasmic Reticulum Regulation Of Slow-twitch Skeletal Muscle Fiber Contraction Positive Regulation Of Cardiac Muscle Cell Contraction Membrane Raft Polarization Geranyl Diphosphate Metabolic Process Positive Regulation Of Neutrophil Activation Protein Localization To Paranode Region Of Axon Regulation Of Transepithelial Transport Establishment Of Protein Localization To Membrane Peptidase Activator Activity Involved In Apoptotic Process Postsynaptic Endosome Paracellular Tight Junction Channel Activity Lipid Phosphatase Activity Farnesyl Diphosphate Metabolic Process Sphingosine-1-phosphate Phosphatase Activity Regulation Of ATPase-coupled Calcium Transmembrane Transporter Activity Membrane Raft Distribution Clathrin Light Chain Binding Paracellular Transport Lysophosphatidic Acid Phosphatase Activity Membrane Raft Localization Neurotransmitter Receptor Transport, Endosome To Postsynaptic Membrane Neurotransmitter Receptor Transport, Endosome To Plasma Membrane Apical Junction Assembly Retinal Pigment Epithelium Development Paranodal Junction Protein Prenylation Protein Localization To Axon Structural Constituent Of Myelin Sheath Establishment Of Protein Localization To Postsynaptic Membrane Neurotransmitter Receptor Transport To Postsynaptic Membrane Neurotransmitter Receptor Transport To Plasma Membrane Action Potential Propagation Neuronal Action Potential Propagation Regulation Of Neutrophil Activation Membrane Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Central Nervous System Myelination Positive Regulation Of Receptor Recycling Endosome To Plasma Membrane Protein Transport	Membrane Plasma Membrane Protein Binding PH-gated Chloride Channel Activity Connexin Complex Gap Junction Channel Activity Gap Junction Immune Response-activating Cell Surface Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway G Protein-coupled Opioid Receptor Activity G Protein-coupled Receptor Activity Immune Response-regulating Cell Surface Receptor Signaling Pathway G Protein-coupled Opioid Receptor Signaling Pathway Immune System Process Immune Response-regulating Signaling Pathway
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