BTN2A1 and STRIT1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		BTN2A1	STRIT1
Description		butyrophilin subfamily 2 member A1	small transmembrane regulator of ion transport 1
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GO Annotations	Cellular Component	Plasma Membrane External Side Of Plasma Membrane Membrane	Membrane Sarcoplasmic Reticulum Sarcoplasmic Reticulum Membrane
	Molecular Function	Signaling Receptor Binding Protein Binding	Protein Binding Enzyme Activator Activity
	Biological Process	Regulation Of Cytokine Production Lipid Metabolic Process T Cell Receptor Signaling Pathway	Regulation Of Slow-twitch Skeletal Muscle Fiber Contraction Positive Regulation Of Calcium Ion Import Positive Regulation Of Cardiac Muscle Cell Contraction Regulation Of ATPase-coupled Calcium Transmembrane Transporter Activity Positive Regulation Of Calcium Ion Import Into Sarcoplasmic Reticulum
Pathways		Butyrophilin (BTN) family interactions
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Brain morphology (MOSTest) ( 32665545) Chronic obstructive pulmonary disease ( 33909500) Cutaneous mastocytosis ( 32752121) Fish- and plant-related diet ( 32066663) Gastroesophageal reflux disease ( 31527586 34187846) General cognitive ability ( 29844566) Intelligence (MTAG) ( 29326435) Lung cancer ( 31577861) Lung cancer in ever smokers ( 28604730) Refractive error ( 32231278) Subcortical volume (MOSTest) ( 32665545) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		6 interacting genes: CLDN19 CTXN3 MAL NSG1 PLPP6 STRIT1	47 interacting genes: ANK1 ANKS6 AQP12B AQP6 ARL13B BIK BSCL2 BTN2A1 CD53 CD69 CD79A CMTM2 EDA2R ERGIC3 F11R FAM209A FFAR2 FXYD3 GOLM1 GPR42 GPR61 HSD17B11 HSD17B13 IFNGR2 ISLR2 JPH1 KCNJ6 KCNK5 MFF MOG MSMO1 MTIF3 PDZK1IP1 PI16 SCN3B SLC14A1 SLC34A2 SLC35H1 SLC38A1 SPNS3 STX1A STX2 TM4SF18 TMEM101 TMEM237 TMEM51 TSPAN15
Entrez ID		11120	100507537
HPRD ID		12544
Ensembl ID		ENSG00000112763	ENSG00000240045
Uniprot IDs		Q7KYR7	P0DN84
PDB IDs		8DFW 8DFX 8DFY 8JYC 8JYE 8VC7	7MPA
Enriched GO Terms of Interacting Partners?		Schmidt-Lanterman Incisure Protein Insertion Into Plasma Membrane Hinge Region Between Urothelial Plaques Of Apical Plasma Membrane Postsynaptic Neurotransmitter Receptor Cycle Neurotransmitter Receptor Cycle Isoprenoid Diphosphate Phosphatase Activity Farnesyl Diphosphate Catabolic Process Geranylgeranyl Diphosphate Catabolic Process Spontaneous Synaptic Transmission Mesaxon Positive Regulation Of Calcium Ion Import Into Sarcoplasmic Reticulum Regulation Of Slow-twitch Skeletal Muscle Fiber Contraction Positive Regulation Of Cardiac Muscle Cell Contraction Membrane Raft Polarization Geranyl Diphosphate Metabolic Process Positive Regulation Of Neutrophil Activation Protein Localization To Paranode Region Of Axon Regulation Of Transepithelial Transport Establishment Of Protein Localization To Membrane Peptidase Activator Activity Involved In Apoptotic Process Postsynaptic Endosome Paracellular Tight Junction Channel Activity Lipid Phosphatase Activity Farnesyl Diphosphate Metabolic Process Sphingosine-1-phosphate Phosphatase Activity Regulation Of ATPase-coupled Calcium Transmembrane Transporter Activity Membrane Raft Distribution Clathrin Light Chain Binding Paracellular Transport Lysophosphatidic Acid Phosphatase Activity Membrane Raft Localization Neurotransmitter Receptor Transport, Endosome To Postsynaptic Membrane Neurotransmitter Receptor Transport, Endosome To Plasma Membrane Apical Junction Assembly Retinal Pigment Epithelium Development Paranodal Junction Protein Prenylation Protein Localization To Axon Structural Constituent Of Myelin Sheath Establishment Of Protein Localization To Postsynaptic Membrane Neurotransmitter Receptor Transport To Postsynaptic Membrane Neurotransmitter Receptor Transport To Plasma Membrane Action Potential Propagation Neuronal Action Potential Propagation Regulation Of Neutrophil Activation Membrane Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Central Nervous System Myelination Positive Regulation Of Receptor Recycling Endosome To Plasma Membrane Protein Transport	Membrane Plasma Membrane Protein Binding Protein Localization To Membrane Steroid Dehydrogenase Activity Transmembrane Transport Water Transport Fluid Transport Protein Localization To Cell Periphery
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