STRIT1 and JPH1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		STRIT1	JPH1
Description		small transmembrane regulator of ion transport 1	junctophilin 1
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GO Annotations	Cellular Component	Membrane Sarcoplasmic Reticulum Sarcoplasmic Reticulum Membrane	Nucleoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Junctional Sarcoplasmic Reticulum Membrane Membrane Sarcoplasmic Reticulum Z Disc Junctional Membrane Complex Sarcoplasmic Reticulum Membrane
	Molecular Function	Protein Binding Enzyme Activator Activity	Protein Binding Structural Constituent Of Muscle
	Biological Process	Regulation Of Slow-twitch Skeletal Muscle Fiber Contraction Positive Regulation Of Calcium Ion Import Positive Regulation Of Cardiac Muscle Cell Contraction Regulation Of ATPase-coupled Calcium Transmembrane Transporter Activity Positive Regulation Of Calcium Ion Import Into Sarcoplasmic Reticulum	Muscle Organ Development Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Calcium Ion Transport Into Cytosol
Pathways
Drugs
Diseases
GWAS			Carotid plaque burden (smoking interaction) ( 24954085) Uterine fibroids ( 28836065)
Interacting Genes		47 interacting genes: ANK1 ANKS6 AQP12B AQP6 ARL13B BIK BSCL2 BTN2A1 CD53 CD69 CD79A CMTM2 EDA2R ERGIC3 F11R FAM209A FFAR2 FXYD3 GOLM1 GPR42 GPR61 HSD17B11 HSD17B13 IFNGR2 ISLR2 JPH1 KCNJ6 KCNK5 MFF MOG MSMO1 MTIF3 PDZK1IP1 PI16 SCN3B SLC14A1 SLC34A2 SLC35H1 SLC38A1 SPNS3 STX1A STX2 TM4SF18 TMEM101 TMEM237 TMEM51 TSPAN15	17 interacting genes: AQP6 EDDM3B EMP1 GPR42 HTATIP2 LEPROTL1 MEOX2 NAT8 PLP1 RSPH1 SLC16A13 STRIT1 TMEM120B TMEM65 TTN UACA UBC
Entrez ID		100507537	56704
HPRD ID			07286
Ensembl ID		ENSG00000240045	ENSG00000104369
Uniprot IDs		P0DN84	Q86VR1 Q9HDC5
PDB IDs		7MPA	7RW4
Enriched GO Terms of Interacting Partners?		Membrane Plasma Membrane Protein Binding Protein Localization To Membrane Steroid Dehydrogenase Activity Transmembrane Transport Water Transport Fluid Transport Protein Localization To Cell Periphery
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