STRIT1 and SLC38A1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		STRIT1	SLC38A1
Description		small transmembrane regulator of ion transport 1	solute carrier family 38 member 1
Image			No pdb structure
GO Annotations	Cellular Component	Membrane Sarcoplasmic Reticulum Sarcoplasmic Reticulum Membrane	Plasma Membrane Membrane Basolateral Plasma Membrane Axon Neuronal Cell Body Extracellular Exosome External Side Of Apical Plasma Membrane
	Molecular Function	Protein Binding Enzyme Activator Activity	Amino Acid:sodium Symporter Activity Neutral L-amino Acid:sodium Symporter Activity Proline:sodium Symporter Activity Protein Binding Amino Acid Transmembrane Transporter Activity Neutral L-amino Acid Transmembrane Transporter Activity L-amino Acid Transmembrane Transporter Activity L-glutamine Transmembrane Transporter Activity Symporter Activity Glycine:sodium Symporter Activity Alanine:sodium Symporter Activity
	Biological Process	Regulation Of Slow-twitch Skeletal Muscle Fiber Contraction Positive Regulation Of Calcium Ion Import Positive Regulation Of Cardiac Muscle Cell Contraction Regulation Of ATPase-coupled Calcium Transmembrane Transporter Activity Positive Regulation Of Calcium Ion Import Into Sarcoplasmic Reticulum	Neurotransmitter Uptake Amino Acid Transmembrane Transport Monoatomic Ion Transport Sodium Ion Transport Amino Acid Transport Glutamine Transport Female Pregnancy Gamma-aminobutyric Acid Biosynthetic Process Neutral Amino Acid Transport Glycine Transport Regulation Of Synaptic Transmission, GABAergic Alanine Transport Sodium Ion Transmembrane Transport Amino Acid Import Regulation Of Synaptic Plasticity Transport Across Blood-brain Barrier L-alpha-amino Acid Transmembrane Transport L-glutamine Import Across Plasma Membrane
Pathways			Astrocytic Glutamate-Glutamine Uptake And Metabolism Amino acid transport across the plasma membrane
Drugs			Asparagine
Diseases
GWAS			Appendicular lean mass ( 33097823) Birth weight ( 31043758) Gout ( 32238385) Morning person ( 30696823) Offspring birth weight ( 31043758) Refractive error ( 32231278)
Interacting Genes		47 interacting genes: ANK1 ANKS6 AQP12B AQP6 ARL13B BIK BSCL2 BTN2A1 CD53 CD69 CD79A CMTM2 EDA2R ERGIC3 F11R FAM209A FFAR2 FXYD3 GOLM1 GPR42 GPR61 HSD17B11 HSD17B13 IFNGR2 ISLR2 JPH1 KCNJ6 KCNK5 MFF MOG MSMO1 MTIF3 PDZK1IP1 PI16 SCN3B SLC14A1 SLC34A2 SLC35H1 SLC38A1 SPNS3 STX1A STX2 TM4SF18 TMEM101 TMEM237 TMEM51 TSPAN15	30 interacting genes: AMIGO1 AQP6 BMP10 C1QL4 CD79A CREB3 FATE1 FFAR2 GPR152 GPR42 GRM2 IGFBP5 IL1RL1 PDCD1LG2 PGRMC2 PMP22 PTPN11 RPRM SCGB1D1 SCN3B SERP2 SLC10A1 SLC10A6 SLC13A4 SMIM3 SSMEM1 STRIT1 TMEM60 TMPPE TRARG1
Entrez ID		100507537	81539
HPRD ID			12245
Ensembl ID		ENSG00000240045	ENSG00000111371
Uniprot IDs		P0DN84	F8VX04 Q9H2H9
PDB IDs		7MPA
Enriched GO Terms of Interacting Partners?		Membrane Plasma Membrane Protein Binding Protein Localization To Membrane Steroid Dehydrogenase Activity Transmembrane Transport Water Transport Fluid Transport Protein Localization To Cell Periphery	Membrane Bile Acid:sodium Symporter Activity
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