STRIT1 and GPR61

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		STRIT1	GPR61
Description		small transmembrane regulator of ion transport 1	G protein-coupled receptor 61
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GO Annotations	Cellular Component	Membrane Sarcoplasmic Reticulum Sarcoplasmic Reticulum Membrane	Endosome Plasma Membrane Endosome Membrane Membrane Receptor Complex
	Molecular Function	Protein Binding Enzyme Activator Activity	G Protein-coupled Receptor Activity Protein Binding Arrestin Family Protein Binding
	Biological Process	Regulation Of Slow-twitch Skeletal Muscle Fiber Contraction Positive Regulation Of Calcium Ion Import Positive Regulation Of Cardiac Muscle Cell Contraction Regulation Of ATPase-coupled Calcium Transmembrane Transporter Activity Positive Regulation Of Calcium Ion Import Into Sarcoplasmic Reticulum	Signal Transduction G Protein-coupled Receptor Signaling Pathway Ligand-independent Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway
Pathways
Drugs
Diseases
GWAS			Adult body size ( 32376654) Body mass index ( 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index in physically active individuals ( 28448500) Body size at age 10 ( 32376654) Childhood body mass index ( 26604143) Chronotype ( 30696823) Hepcidin/ferritin ratio ( 27846281) Morning person ( 30696823) Schizophrenia, bipolar disorder or major depressive disorder x sex interaction (3df) ( 34099189) Stearic acid (18:0) levels ( 23362303) Waist circumference ( 25673412)
Interacting Genes		47 interacting genes: ANK1 ANKS6 AQP12B AQP6 ARL13B BIK BSCL2 BTN2A1 CD53 CD69 CD79A CMTM2 EDA2R ERGIC3 F11R FAM209A FFAR2 FXYD3 GOLM1 GPR42 GPR61 HSD17B11 HSD17B13 IFNGR2 ISLR2 JPH1 KCNJ6 KCNK5 MFF MOG MSMO1 MTIF3 PDZK1IP1 PI16 SCN3B SLC14A1 SLC34A2 SLC35H1 SLC38A1 SPNS3 STX1A STX2 TM4SF18 TMEM101 TMEM237 TMEM51 TSPAN15	20 interacting genes: APP ARL6IP6 ARLN ATP6V0B CLDND1 CTXN3 EMP3 FCER1G GJA8 GJB6 KLRC1 PLP1 PMP22 SCN3B SLC12A7 SLC13A4 STRIT1 TMEM147 TMEM218 TRARG1
Entrez ID		100507537	83873
HPRD ID			06077
Ensembl ID		ENSG00000240045	ENSG00000156097
Uniprot IDs		P0DN84	G4XH66 Q9BZJ8
PDB IDs		7MPA	8KGK 8TB0 8TB7
Enriched GO Terms of Interacting Partners?		Membrane Plasma Membrane Protein Binding Protein Localization To Membrane Steroid Dehydrogenase Activity Transmembrane Transport Water Transport Fluid Transport Protein Localization To Cell Periphery	Membrane Plasma Membrane Gap Junction-mediated Intercellular Transport Cell-cell Signaling Signaling Bleb Assembly Intercellular Transport Cell Communication Transmembrane Transport Connexin Complex Gap Junction Channel Activity Chemical Synaptic Transmission Protein Localization To Membrane Gap Junction Trans-synaptic Signaling Synaptic Signaling
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