STRIT1 and SLC14A1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		STRIT1	SLC14A1
Description		small transmembrane regulator of ion transport 1	solute carrier family 14 member 1 (Kidd blood group)
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GO Annotations	Cellular Component	Membrane Sarcoplasmic Reticulum Sarcoplasmic Reticulum Membrane	Plasma Membrane Membrane Basolateral Plasma Membrane
	Molecular Function	Protein Binding Enzyme Activator Activity	Water Transmembrane Transporter Activity Protein Binding Urea Transmembrane Transporter Activity Urea Channel Activity
	Biological Process	Regulation Of Slow-twitch Skeletal Muscle Fiber Contraction Positive Regulation Of Calcium Ion Import Positive Regulation Of Cardiac Muscle Cell Contraction Regulation Of ATPase-coupled Calcium Transmembrane Transporter Activity Positive Regulation Of Calcium Ion Import Into Sarcoplasmic Reticulum	Water Transport Urea Transport Establishment Of Localization In Cell Transmembrane Transport Urea Transmembrane Transport
Pathways			SLC-mediated transport of organic cations
Drugs
Diseases
GWAS			Bladder cancer ( 21750109 21824976) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Mean corpuscular hemoglobin concentration ( 29403010) Pursuit maintenance gain ( 29064472) Sum of carotid plaque area ( 32469969) Sum of stenosis ( 32469969)
Interacting Genes		47 interacting genes: ANK1 ANKS6 AQP12B AQP6 ARL13B BIK BSCL2 BTN2A1 CD53 CD69 CD79A CMTM2 EDA2R ERGIC3 F11R FAM209A FFAR2 FXYD3 GOLM1 GPR42 GPR61 HSD17B11 HSD17B13 IFNGR2 ISLR2 JPH1 KCNJ6 KCNK5 MFF MOG MSMO1 MTIF3 PDZK1IP1 PI16 SCN3B SLC14A1 SLC34A2 SLC35H1 SLC38A1 SPNS3 STX1A STX2 TM4SF18 TMEM101 TMEM237 TMEM51 TSPAN15	12 interacting genes: BTN2A2 C1GALT1 CFTR FIS1 GIMAP1 MIP RTP2 SNORC STRIT1 THSD7B TMEM97 TMIE
Entrez ID		100507537	6563
HPRD ID			00195
Ensembl ID		ENSG00000240045	ENSG00000141469
Uniprot IDs		P0DN84	B4DFJ8 B4DHU3 F5GWS2 G0W2N5 Q13336
PDB IDs		7MPA	6QD5 8BLP 8XDF
Enriched GO Terms of Interacting Partners?		Membrane Plasma Membrane Protein Binding Protein Localization To Membrane Steroid Dehydrogenase Activity Transmembrane Transport Water Transport Fluid Transport Protein Localization To Cell Periphery	Membrane Water Transport
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