NUPL2 and NUP214

Number of citations of the paper that reports this interaction (PMID 10228171)
142

Data Source:
BioGRID (two hybrid)

		NUPL2	NUP214
Gene Name		nucleoporin like 2	nucleoporin 214kDa
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nuclear Pore Nucleoplasm Cytoplasm Cytosol Nuclear Membrane	Nucleus Nuclear Pore Nucleoplasm Cytosol Focal Adhesion Intracellular Membrane-bounded Organelle
	Molecular Function	Nuclear Export Signal Receptor Activity Poly(A) RNA Binding Metal Ion Binding	Transporter Activity Nucleocytoplasmic Transporter Activity Protein Binding
	Biological Process	Mitotic Cell Cycle Carbohydrate Metabolic Process Protein Export From Nucleus Mitotic Nuclear Envelope Disassembly Hexose Transport Pathogenesis Gene Expression Regulation Of Glucose Transport Glucose Transport Viral Process Viral Life Cycle Viral Transcription Cytokine-mediated Signaling Pathway Small Molecule Metabolic Process MRNA Transport Transmembrane Transport	Mitotic Cell Cycle Carbohydrate Metabolic Process MRNA Export From Nucleus Protein Import Into Nucleus Protein Export From Nucleus Mitotic Nuclear Envelope Disassembly Hexose Transport Pathogenesis Gene Expression Regulation Of Glucose Transport Glucose Transport Viral Process Viral Life Cycle Viral Transcription Cytokine-mediated Signaling Pathway Small Molecule Metabolic Process Regulation Of Cell Cycle Transmembrane Transport
Pathways		Mitotic Prophase HIV Infection Nuclear import of Rev protein Regulatory RNA pathways Rev-mediated nuclear export of HIV RNA Nuclear Envelope Breakdown SLC-mediated transmembrane transport M Phase Influenza Life Cycle HIV Life Cycle Influenza Viral RNA Transcription and Replication Rev-mediated nuclear export of HIV RNA Myoclonic epilepsy of Lafora Glycogen storage diseases Transcriptional regulation by small RNAs Vpr-mediated nuclear import of PICs ISG15 antiviral mechanism Interferon Signaling Host Interactions of HIV factors Nuclear Pore Complex (NPC) Disassembly Regulation of Glucokinase by Glucokinase Regulatory Protein Cytokine Signaling in Immune system Interactions of Vpr with host cellular proteins Interactions of Rev with host cellular proteins Influenza Infection Hexose transport Cell Cycle, Mitotic Late Phase of HIV Life Cycle Antiviral mechanism by IFN-stimulated genes Viral Messenger RNA Synthesis Metabolism of carbohydrates Glucose transport	Mitotic Prophase HIV Infection Nuclear import of Rev protein Regulatory RNA pathways Rev-mediated nuclear export of HIV RNA Nuclear Envelope Breakdown SLC-mediated transmembrane transport HuR stabilizes mRNA M Phase Influenza Life Cycle HIV Life Cycle Influenza Viral RNA Transcription and Replication Rev-mediated nuclear export of HIV RNA Myoclonic epilepsy of Lafora Glycogen storage diseases Transcriptional regulation by small RNAs Regulation of mRNA stability by proteins that bind AU-rich elements Vpr-mediated nuclear import of PICs ISG15 antiviral mechanism Interferon Signaling Host Interactions of HIV factors Regulation of Glucokinase by Glucokinase Regulatory Protein Nuclear Pore Complex (NPC) Disassembly Cytokine Signaling in Immune system Interactions of Vpr with host cellular proteins Interactions of Rev with host cellular proteins Influenza Infection Hexose transport Cell Cycle, Mitotic Late Phase of HIV Life Cycle Antiviral mechanism by IFN-stimulated genes Viral Messenger RNA Synthesis Metabolism of carbohydrates Glucose transport
Drugs
Diseases
GWAS
Protein-Protein Interactions		3 interactors: APC GLE1 NUP214	19 interactors: APC CLEC4G DDX19B IPO5 NFX1 NUP107 NUP88 NUPL2 NXF1 NXF2 NXF3 SMAD2 SMAD3 SMAD4 TNPO1 XPO1 XPO5 XPOT ZFP36
Entrez ID		11097	8021
HPRD ID		14855	00258
Ensembl ID		ENSG00000136243	ENSG00000126883
Uniprot IDs		B4DT96 O15504	P35658
PDB IDs			2OIT 3FHC 3FMO 3FMP
Enriched GO Terms of Interacting Partners?		MRNA Export From Nucleus RNA Export From Nucleus Nuclear Export MRNA Transport RNA Transport RNA Localization Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Apoptotic Process Nucleocytoplasmic Transport Nuclear Transport Negative Regulation Of Odontogenesis Metaphase/anaphase Transition Of Mitotic Cell Cycle Canonical Wnt Signaling Pathway Involved In Negative Regulation Of Apoptotic Process Poly(A)+ MRNA Export From Nucleus Negative Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Positive Regulation Of Microtubule Polymerization Positive Regulation Of Pseudopodium Assembly Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Mitotic Cell Cycle Process Cytoplasmic Transport Regulation Of Attachment Of Spindle Microtubules To Kinetochore Mitotic Cell Cycle Muscle Cell Cellular Homeostasis Regulation Of Microtubule Polymerization Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Regulation Of Odontogenesis Negative Regulation Of Microtubule Depolymerization Mitotic Spindle Assembly Checkpoint Mitotic Nuclear Envelope Disassembly Regulation Of Cell Cycle Spindle Assembly Checkpoint Cytoplasmic Microtubule Organization Protein Export From Nucleus Mitotic Spindle Checkpoint Mitotic Cytokinesis Negative Regulation Of Chromosome Segregation Nuclear Envelope Disassembly Negative Regulation Of Microtubule Polymerization Or Depolymerization Cell Cycle Process Regulation Of Mitotic Sister Chromatid Separation Proximal/distal Pattern Formation Spindle Checkpoint Negative Regulation Of Mitotic Nuclear Division Tight Junction Assembly Regulation Of Mitotic Metaphase/anaphase Transition Thymus Development Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process T Cell Differentiation In Thymus Regulation Of Osteoclast Differentiation	Nucleocytoplasmic Transport Nuclear Transport Nuclear Export RNA Transport RNA Localization MRNA Transport Cytoplasmic Transport RNA Export From Nucleus Viral Process Gene Expression MRNA Export From Nucleus Establishment Of Localization In Cell Intracellular Transport Cellular Localization Protein Transport SMAD Protein Complex Assembly Establishment Of Protein Localization Gene Silencing By RNA Protein Localization Transport Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Gene Silencing Positive Regulation Of Epithelial To Mesenchymal Transition Protein Export From Nucleus Gene Silencing By MiRNA Mitotic Nuclear Envelope Disassembly Transforming Growth Factor Beta Receptor Signaling Pathway Posttranscriptional Gene Silencing Nuclear Envelope Disassembly Positive Regulation Of Stem Cell Differentiation SMAD Protein Signal Transduction Regulation Of Epithelial To Mesenchymal Transition Primary MiRNA Processing Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Regulation Of Cellular Response To Growth Factor Stimulus Viral Life Cycle Regulation Of Nucleocytoplasmic Transport Negative Regulation Of Transcription From RNA Polymerase II Promoter Nuclear Envelope Organization Somatic Stem Cell Maintenance Regulation Of Transforming Growth Factor Beta2 Production Paraxial Mesoderm Morphogenesis Poly(A)+ MRNA Export From Nucleus Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Glucose Transport Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Endoderm Development Hexose Transport Embryonic Pattern Specification
Tagcloud ?			acted bona breakpoints chimeras deregulate fg fide functioned gly heterodimerization hox hoxa9 nih nucleoporin nucleoporins nup153 nup98 oncogenesis oncoproteins pbx phe physically recruit repeat repeats segments transactivation transactivators vp16
Tagcloud (Difference) ?			acted bona breakpoints chimeras deregulate fg fide functioned gly heterodimerization hox hoxa9 nih nucleoporin nucleoporins nup153 nup98 oncogenesis oncoproteins pbx phe physically recruit repeat repeats segments transactivation transactivators vp16
Tagcloud (Intersection) ?