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MIR19A and EPRS1
Number of citations of the paper that reports this interaction (PubMedID
28431233
)
0
Data Source:
BioGRID
(unspecified method)
MIR19A
EPRS1
Description
microRNA 19a
glutamyl-prolyl-tRNA synthetase 1
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Space
RISC Complex
Extracellular Exosome
Extracellular Vesicle
Cytoplasm
Cytosol
Plasma Membrane
Membrane
Aminoacyl-tRNA Synthetase Multienzyme Complex
GAIT Complex
Ribonucleoprotein Complex
Molecular Function
MRNA 3'-UTR Binding
MRNA Base-pairing Post-transcriptional Repressor Activity
Nucleotide Binding
RNA Binding
Catalytic Activity
Aminoacyl-tRNA Ligase Activity
Glutamate-tRNA Ligase Activity
Proline-tRNA Ligase Activity
Protein Binding
ATP Binding
Zinc Ion Binding
Ligase Activity
RNA Stem-loop Binding
Identical Protein Binding
Protein Homodimerization Activity
Metal Ion Binding
GTPase Binding
Biological Process
Negative Regulation Of Inflammatory Response To Antigenic Stimulus
Negative Regulation Of Gene Expression
Negative Regulation Of Cardiac Muscle Cell Apoptotic Process
Negative Regulation Of Fibroblast Migration
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Negative Regulation Of Interleukin-6 Production
Negative Regulation Of Toll-like Receptor Signaling Pathway
MiRNA-mediated Post-transcriptional Gene Silencing
MiRNA-mediated Gene Silencing By MRNA Destabilization
B Cell Activation
Negative Regulation Of Apoptotic Process
Negative Regulation Of Inflammatory Response
Positive Regulation Of B Cell Receptor Signaling Pathway
Positive Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development
Negative Regulation Of Cardiac Epithelial To Mesenchymal Transition
Cellular Response To Bacterial Lipopeptide
Negative Regulation Of Extracellular Matrix Assembly
Negative Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway
Negative Regulation Of Sprouting Angiogenesis
Regulation Of Cardiac Conduction
Negative Regulation Of Cellular Response To Transforming Growth Factor Beta Stimulus
Negative Regulation Of Matrix Metallopeptidase Secretion
Translation
Regulation Of Translation
TRNA Aminoacylation For Protein Translation
Glutamyl-tRNA Aminoacylation
Prolyl-tRNA Aminoacylation
Negative Regulation Of Translation
Cellular Response To Insulin Stimulus
TRNA Aminoacylation
Cellular Response To Type II Interferon
Regulation Of Long-chain Fatty Acid Import Into Cell
Pathways
Selenoamino acid metabolism
Cytosolic tRNA aminoacylation
tRNA modification in the nucleus and cytosol
Transcriptional and post-translational regulation of MITF-M expression and activity
Drugs
Glutamic acid
Proline
5'-O-(L-Prolylsulfamoyl)adenosine
5'-O-(L-Cysteinylsulfamoyl)adenosine
5'-O-(N-(Alanyl)sulfamoyl)adenosine
Diseases
GWAS
Interacting Genes
99 interacting genes:
AGO2
AIMP2
APOBEC3B
ATXN2L
C1QBP
CELF1
CELF2
CPSF1
CPSF2
CPSF3
CPSF4
CPSF6
CPSF7
CRTAP
CSTF2
CSTF3
DARS1
DDX1
DDX21
DDX3X
DHX36
EIF2AK2
EPRS1
ERAL1
FAM98A
FIP1L1
FUS
G3BP2
HNRNPA0
HNRNPA1
HNRNPA2B1
HNRNPA3
HNRNPF
HNRNPH1
HNRNPH2
HNRNPH3
HNRNPK
HNRNPL
HNRNPM
HNRNPR
IARS1
IGF2BP1
IGF2BP2
IGF2BP3
KARS1
KNOP1
LARP7
LIN28A
LRPPRC
MARS1
MATR3
MSI1
MSI2
NOL6
NONO
NUDT21
NUFIP2
P3H1
PDCD11
PLOD1
PRMT1
PTBP1
PTBP3
PUF60
PURA
QARS1
RARS1
RBBP6
RBFOX2
RBM12B
RBM14
RBM4
RBMS2
RTCB
SF3B1
SF3B2
SF3B3
SF3B4
SFPQ
SPOUT1
STRBP
SUGP2
SYMPK
SYNCRIP
TAF15
TRA2A
TRA2B
U2SURP
UPF1
UTP20
WDR33
WWP1
WWP2
YBX1
YBX2
YBX3
ZFR
ZNF346
ZNF385A
93 interacting genes:
AIMP2
ARL4D
BTG3
CDC42
CEBPA
DUS2
DUX4
EEF1D
HSP90AA1
HUNK
IARS1
LINC01016
LINC01554
MIR1-1
MIR1-2
MIR106A
MIR106B
MIR107
MIR10B
MIR122
MIR128-1
MIR128-2
MIR138-1
MIR138-2
MIR140
MIR141
MIR143
MIR145
MIR155
MIR15A
MIR15B
MIR16-1
MIR16-2
MIR17
MIR18A
MIR18B
MIR199A1
MIR199A2
MIR19A
MIR19B1
MIR19B2
MIR200A
MIR200B
MIR200C
MIR205
MIR206
MIR20A
MIR20B
MIR21
MIR214
MIR221
MIR222
MIR25
MIR29A
MIR29B1
MIR29B2
MIR29C
MIR31
MIR34A
MIR34B
MIR34C
MIR363
MIR429
MIR451A
MIR7-1
MIR7-2
MIR7-3
MIR9-1
MIR9-2
MIR9-3
MIR92A1
MIR92A2
MIR93
MIR98
MIRLET7A1
MIRLET7A2
MIRLET7A3
MIRLET7B
MIRLET7C
MIRLET7D
MIRLET7E
MIRLET7F1
MIRLET7F2
MIRLET7G
MIRLET7I
NEDD4
NELFCD
PTEN
RARS1
RNF10
SUMO2
SYNCRIP
TAB1
Entrez ID
406979
2058
HPRD ID
00703
Ensembl ID
ENSG00000284204
ENSG00000136628
Uniprot IDs
P07814
PDB IDs
1FYJ
4HVC
4K86
4K87
4K88
5A1N
5A34
5A5H
5BMU
5V58
5VAD
5Y6L
6IY6
7BBU
7F98
7F99
7F9A
7F9B
7F9C
7F9D
7OSY
7OSZ
7OT0
7OT1
7OT2
7OT3
7X09
7X1O
7Y1H
7Y1W
7Y28
7Y3S
Enriched GO Terms of Interacting Partners
?
RNA Binding
Nucleic Acid Binding
RNA Processing
RNA Metabolic Process
MRNA Processing
MRNA Metabolic Process
Nucleic Acid Metabolic Process
Nucleobase-containing Compound Metabolic Process
RNA Splicing
MRNA Binding
Nucleus
Macromolecule Metabolic Process
Regulation Of RNA Splicing
Regulation Of MRNA Metabolic Process
Ribonucleoprotein Complex
MRNA Cleavage And Polyadenylation Specificity Factor Complex
Nucleoplasm
Post-transcriptional Regulation Of Gene Expression
MRNA Splicing, Via Spliceosome
Regulation Of Translation
RNA Splicing, Via Transesterification Reactions
MRNA 3'-UTR Binding
Regulation Of MRNA Processing
Regulation Of MRNA Splicing, Via Spliceosome
Aminoacyl-tRNA Synthetase Multienzyme Complex
Cytoplasmic Stress Granule
Spliceosomal Complex
MiRNA Binding
Negative Regulation Of MRNA Metabolic Process
Catalytic Step 2 Spliceosome
Negative Regulation Of Translation
Negative Regulation Of RNA Catabolic Process
RNA Stabilization
RNA 3'-end Processing
Regulation Of Alternative MRNA Splicing, Via Spliceosome
MRNA 3'-end Processing
Co-transcriptional RNA 3'-end Processing, Cleavage And Polyadenylation Pathway
Regulation Of Gene Expression
Regulation Of Macromolecule Metabolic Process
Regulation Of Primary Metabolic Process
Negative Regulation Of MRNA Catabolic Process
Regulation Of Macromolecule Biosynthetic Process
Regulation Of MRNA Stability
MRNA Stabilization
Regulation Of RNA Stability
Pre-mRNA Binding
Positive Regulation Of Cytoplasmic Translation
Co-transcriptional MRNA 3'-end Processing, Cleavage And Polyadenylation Pathway
Regulation Of Metabolic Process
Regulation Of Cytoplasmic Translation
MiRNA-mediated Post-transcriptional Gene Silencing
RISC Complex
Regulatory NcRNA-mediated Post-transcriptional Gene Silencing
Post-transcriptional Gene Silencing
Regulatory NcRNA-mediated Gene Silencing
MRNA Base-pairing Post-transcriptional Repressor Activity
Post-transcriptional Regulation Of Gene Expression
Negative Regulation Of Gene Expression
MRNA 3'-UTR Binding
MiRNA-mediated Gene Silencing By Inhibition Of Translation
Negative Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Biosynthetic Process
Negative Regulation Of Macromolecule Metabolic Process
MiRNA-mediated Gene Silencing By MRNA Destabilization
Negative Regulation Of Metabolic Process
Extracellular Vesicle
Negative Regulation Of Translation
Regulation Of Gene Expression
Regulation Of Macromolecule Biosynthetic Process
MRNA Destabilization
RNA Destabilization
Positive Regulation Of MRNA Catabolic Process
Negative Regulation Of Cell Migration
Negative Regulation Of Cell Motility
Regulation Of Macromolecule Metabolic Process
Negative Regulation Of Locomotion
Negative Regulation Of Angiogenesis
Negative Regulation Of Vasculature Development
Negative Regulation Of Cytokine Production
Positive Regulation Of MRNA Metabolic Process
Negative Regulation Of Vascular Endothelial Growth Factor Production
Regulation Of Angiogenesis
Regulation Of Vasculature Development
Regulation Of MRNA Stability
Regulation Of Metabolic Process
Regulation Of Translation
Regulation Of RNA Stability
Negative Regulation Of Multicellular Organismal Process
Negative Regulation Of Developmental Process
Negative Regulation Of Protein Metabolic Process
Regulation Of Blood Vessel Endothelial Cell Migration
Regulation Of Cell Migration
Regulation Of Endothelial Cell Migration
Regulation Of Cellular Response To Growth Factor Stimulus
Regulation Of Cell Motility
Negative Regulation Of Blood Vessel Endothelial Cell Migration
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Negative Regulation Of Cell Population Proliferation
Negative Regulation Of Endothelial Cell Migration
Regulation Of MRNA Metabolic Process
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