IL24 and HMMR

Number of citations of the paper that reports this interaction (PubMedID 25640309)
0

Data Source:
BioGRID (two hybrid)

		IL24	HMMR
Description		interleukin 24	hyaluronan mediated motility receptor
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Cytoplasm Centrosome Spindle Cytosol Cytoskeleton Plasma Membrane Cell Surface Microtubule Cytoskeleton Membrane
	Molecular Function	Cytokine Activity Protein Binding	Protein Binding Hyaluronic Acid Binding Cargo Receptor Activity
	Biological Process	Apoptotic Process Immune Response Signal Transduction Positive Regulation Of Cell Population Proliferation Negative Regulation Of Cell Population Proliferation Negative Regulation Of Cell Migration Cellular Response To Lipopolysaccharide Cellular Response To Interleukin-4	Receptor-mediated Endocytosis Hyaluronan Catabolic Process
Pathways		Interleukin-20 family signaling	Hyaluronan metabolism Hyaluronan degradation AURKA Activation by TPX2
Drugs			Hyaluronic acid
Diseases
GWAS		Inflammatory bowel disease ( 23128233)	Metabolite levels ( 23823483)
Interacting Genes		28 interacting genes: AKT1 APC ATM BAG4 CASP8 CCR5 CLU DCD ESR2 FBXW7 HMMR HRAS IL20RA KRAS LSP1 NOTCH2 PALB2 PARP1 PIK3CA PTEN RAD51 RARG RB1CC1 RIPK3 S100A6 S100P SMAD4 UBE3A	18 interacting genes: ACTB BACH1 CALM1 CD44 CDH13 CEBPA CFTR GREB1 IL24 ITIH5 MAPK3 MORN4 NAT2 SVIL THRSP TPX2 TRIM54 TUBB2A
Entrez ID		11009	3161
HPRD ID		04995	02963
Ensembl ID		ENSG00000162892	ENSG00000072571
Uniprot IDs		Q13007	O75330
PDB IDs		6DF3 6GG1
Enriched GO Terms of Interacting Partners?		Regulation Of Apoptotic Process Regulation Of Programmed Cell Death Positive Regulation Of Intracellular Signal Transduction Apoptotic Process Programmed Cell Death Cell Death Positive Regulation Of Signal Transduction Regulation Of Intracellular Signal Transduction Positive Regulation Of Cell Communication Positive Regulation Of Signaling Regulation Of Neuron Apoptotic Process Positive Regulation Of Programmed Cell Death Response To Stress Regulation Of Signal Transduction Regulation Of Cell Population Proliferation Positive Regulation Of Apoptotic Process Gland Development Intracellular Signal Transduction Signal Transduction Regulation Of Cell Communication Regulation Of Signaling Protein-containing Complex Binding Negative Regulation Of Programmed Cell Death Animal Organ Development Response To Lipid Regulation Of Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Apoptotic Process Cellular Response To Oxygen-containing Compound Apoptotic Signaling Pathway Positive Regulation Of Cellular Component Biogenesis Identical Protein Binding Response To Gamma Radiation Myelin Maintenance Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Intracellular Signal Transduction Protein-containing Complex Regulation Of Multicellular Organismal Process Regulation Of Apoptotic Signaling Pathway Regulation Of Biological Quality Positive Regulation Of Metabolic Process Positive Regulation Of Biosynthetic Process Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Defense Response Cell Surface Receptor Signaling Pathway Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Response To Radiation	Focal Adhesion Negative Regulation Of Protein-containing Complex Disassembly Regulation Of Protein Depolymerization Calyx Of Held
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