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IL24 and RARG
Number of citations of the paper that reports this interaction (PubMedID
21988832
)
38
Data Source:
BioGRID
(two hybrid)
IL24
RARG
Description
interleukin 24
retinoic acid receptor gamma
Image
GO Annotations
Cellular Component
Extracellular Region
Extracellular Space
Chromatin
Nucleus
Nucleoplasm
Transcription Regulator Complex
Cytoplasm
Membrane
RNA Polymerase II Transcription Regulator Complex
Molecular Function
Cytokine Activity
Protein Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA Binding
Chromatin Binding
DNA-binding Transcription Factor Activity
Nuclear Receptor Activity
Protein Binding
Zinc Ion Binding
Sequence-specific DNA Binding
Metal Ion Binding
Nuclear Retinoid X Receptor Binding
Sequence-specific Double-stranded DNA Binding
Biological Process
Apoptotic Process
Immune Response
Signal Transduction
Positive Regulation Of Cell Population Proliferation
Negative Regulation Of Cell Population Proliferation
Negative Regulation Of Cell Migration
Cellular Response To Lipopolysaccharide
Cellular Response To Interleukin-4
Negative Regulation Of Transcription By RNA Polymerase II
Neural Tube Closure
Chondrocyte Development
Glandular Epithelial Cell Development
Growth Plate Cartilage Development
Growth Plate Cartilage Chondrocyte Growth
Regulation Of DNA-templated Transcription
Apoptotic Process
Cell Population Proliferation
Positive Regulation Of Cell Population Proliferation
Negative Regulation Of Cell Population Proliferation
Regulation Of Cell Size
Anterior/posterior Pattern Specification
Regulation Of Gene Expression
Positive Regulation Of Gene Expression
Programmed Cell Death
Cell Differentiation
Embryonic Camera-type Eye Development
Regulation Of Myelination
Negative Regulation Of Chondrocyte Differentiation
Response To Retinoic Acid
Embryonic Hindlimb Morphogenesis
Multicellular Organism Growth
Positive Regulation Of Apoptotic Process
Positive Regulation Of Programmed Cell Death
Negative Regulation Of Cell Differentiation
Regulation Of Myeloid Cell Differentiation
Positive Regulation Of Transcription By RNA Polymerase II
Embryonic Eye Morphogenesis
Retinoic Acid Receptor Signaling Pathway
Reproductive Structure Development
Gland Development
Canonical Wnt Signaling Pathway
Limb Development
Face Development
Bone Development
Bone Morphogenesis
Epithelium Development
Trachea Cartilage Development
Prostate Gland Epithelium Morphogenesis
Negative Regulation Of Cartilage Development
Harderian Gland Development
Cellular Response To Retinoic Acid
Stem Cell Proliferation
Cellular Response To Leukemia Inhibitory Factor
Negative Regulation Of Stem Cell Proliferation
Pathways
Interleukin-20 family signaling
Nuclear Receptor transcription pathway
Signaling by Retinoic Acid
Activation of anterior HOX genes in hindbrain development during early embryogenesis
Drugs
Adapalene
Acitretin
Alitretinoin
Tretinoin
Tazarotene
Etretinate
Isotretinoin
SR11254
BMS-181156
CD564
Dodecyl-Alpha-D-Maltoside
BMS184394
Palovarotene
LGD-1550
3-Fluoro-4-{[(2R)-2-hydroxy-2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-2-naphthalenyl)acetyl]amino}benzoic acid
3-fluoro-4-[2-hydroxy-2-(5,5,8,8-tetramethyl-5,6,7,8,-tetrahydro-naphtalen-2-yl)-acetylamino]-benzoic acid
Trifarotene
Diseases
GWAS
Inflammatory bowel disease (
23128233
)
Anthracycline-induced cardiotoxicity in childhood cancer (
26237429
)
Cardiorespiratory fitness (800m run time) (
32572135
)
Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) (
31374203
)
Interacting Genes
28 interacting genes:
AKT1
APC
ATM
BAG4
CASP8
CCR5
CLU
DCD
ESR2
FBXW7
HMMR
HRAS
IL20RA
KRAS
LSP1
NOTCH2
PALB2
PARP1
PIK3CA
PTEN
RAD51
RARG
RB1CC1
RIPK3
S100A6
S100P
SMAD4
UBE3A
33 interacting genes:
ACY3
ARID1A
BBS4
HMGA1
IL24
ITGB1BP2
LSR
MAP6
MRPL12
MTMR6
MYF5
NCOA1
NCOA3
NCOR1
NCOR2
NKX3-1
NR0B2
NR2F6
OIP5
PNRC1
PNRC2
PRKAR1B
PSMC5
RHPN2
RXRA
RXRB
RXRG
S100A3
SMAD3
SMARCD3
SPHK1
TNIP1
ZNF576
Entrez ID
11009
5916
HPRD ID
04995
01573
Ensembl ID
ENSG00000162892
ENSG00000172819
Uniprot IDs
Q13007
A8K3H3
B7Z4B4
F1D8P1
P13631
PDB IDs
6DF3
6GG1
1EXA
1EXX
1FCX
1FCY
1FCZ
1FD0
2LBD
3LBD
4LBD
5M24
6FX0
Enriched GO Terms of Interacting Partners
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Regulation Of Apoptotic Process
Regulation Of Programmed Cell Death
Positive Regulation Of Intracellular Signal Transduction
Apoptotic Process
Programmed Cell Death
Cell Death
Positive Regulation Of Signal Transduction
Regulation Of Intracellular Signal Transduction
Positive Regulation Of Cell Communication
Positive Regulation Of Signaling
Regulation Of Neuron Apoptotic Process
Positive Regulation Of Programmed Cell Death
Response To Stress
Regulation Of Signal Transduction
Regulation Of Cell Population Proliferation
Positive Regulation Of Apoptotic Process
Gland Development
Intracellular Signal Transduction
Signal Transduction
Regulation Of Cell Communication
Regulation Of Signaling
Protein-containing Complex Binding
Negative Regulation Of Programmed Cell Death
Animal Organ Development
Response To Lipid
Regulation Of Intrinsic Apoptotic Signaling Pathway
Negative Regulation Of Apoptotic Process
Cellular Response To Oxygen-containing Compound
Apoptotic Signaling Pathway
Positive Regulation Of Cellular Component Biogenesis
Identical Protein Binding
Response To Gamma Radiation
Myelin Maintenance
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of Intracellular Signal Transduction
Protein-containing Complex
Regulation Of Multicellular Organismal Process
Regulation Of Apoptotic Signaling Pathway
Regulation Of Biological Quality
Positive Regulation Of Metabolic Process
Positive Regulation Of Biosynthetic Process
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Defense Response
Cell Surface Receptor Signaling Pathway
Positive Regulation Of Macromolecule Metabolic Process
Positive Regulation Of RNA Biosynthetic Process
Positive Regulation Of DNA-templated Transcription
Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway
Response To Radiation
Nuclear Receptor Binding
Chromatin
Nuclear Retinoid X Receptor Binding
Nuclear Retinoic Acid Receptor Binding
Nuclear Receptor Activity
Nuclear Receptor-mediated Signaling Pathway
Retinoic Acid Receptor Signaling Pathway
Intracellular Receptor Signaling Pathway
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
Positive Regulation Of RNA Biosynthetic Process
Positive Regulation Of DNA-templated Transcription
RNA Polymerase II Transcription Regulator Complex
Retinoic Acid-responsive Element Binding
Regulation Of Gene Expression
Steroid Hormone Receptor Signaling Pathway
Nuclear Receptor-mediated Steroid Hormone Signaling Pathway
Hormone-mediated Signaling Pathway
Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of RNA Metabolic Process
Regulation Of RNA Metabolic Process
Regulation Of Transcription By RNA Polymerase II
Nucleoplasm
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of Macromolecule Metabolic Process
Nucleosome Disassembly
Protein-DNA Complex Disassembly
Nuclear Steroid Receptor Activity
Positive Regulation Of Multicellular Organismal Process
Positive Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of MiRNA Transcription
Positive Regulation Of Biosynthetic Process
Nuclear Thyroid Hormone Receptor Binding
DNA Binding
Sequence-specific DNA Binding
Positive Regulation Of Developmental Process
Regulation Of Response To Nutrient Levels
Regulation Of Metabolic Process
Regulation Of Thyroid Hormone Receptor Signaling Pathway
Positive Regulation Of Vitamin D Receptor Signaling Pathway
Negative Regulation Of Biosynthetic Process
Transcription Coregulator Binding
Positive Regulation Of Bone Mineralization
Nuclear Protein Quality Control By The Ubiquitin-proteasome System
Regulation Of Primary Metabolic Process
Positive Regulation Of Myoblast Differentiation
Somitogenesis
MRNA Transcription By RNA Polymerase II
Positive Regulation Of Transcription By RNA Polymerase II
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