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MIR222 and RBMS2
Number of citations of the paper that reports this interaction (PubMedID
28431233
)
0
Data Source:
BioGRID
(unspecified method)
MIR222
RBMS2
Description
microRNA 222
RNA binding motif single stranded interacting protein 2
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Space
RISC Complex
Extracellular Vesicle
Nucleus
Cytosol
Ribonucleoprotein Complex
Molecular Function
MRNA Base-pairing Post-transcriptional Repressor Activity
Nucleic Acid Binding
RNA Binding
MRNA 3'-UTR Binding
Poly(A) Binding
Poly(U) RNA Binding
Biological Process
Positive Regulation Of Epithelial Cell Migration
Positive Regulation Of Epithelial To Mesenchymal Transition
Negative Regulation Of Angiogenesis
Negative Regulation Of Interleukin-21 Production
MiRNA-mediated Post-transcriptional Gene Silencing
Negative Regulation Of Apoptotic Process
Host-mediated Suppression Of Viral Genome Replication
Positive Regulation Of Erythrocyte Differentiation
Positive Regulation Of Axon Regeneration
Negative Regulation Of Inflammatory Response
Positive Regulation Of Cardiac Muscle Cell Proliferation
Negative Regulation Of Cell Adhesion Molecule Production
Negative Regulation Of Cytokine Production Involved In Inflammatory Response
Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle
Positive Regulation Of Schwann Cell Migration
Negative Regulation Of Hematopoietic Stem Cell Proliferation
Negative Regulation Of TRAIL-activated Apoptotic Signaling Pathway
Negative Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis
Positive Regulation Of Vascular Associated Smooth Muscle Cell Proliferation
Negative Regulation Of Leukocyte Adhesion To Vascular Endothelial Cell
Positive Regulation Of Schwann Cell Proliferation Involved In Axon Regeneration
Negative Regulation Of Cardiac Muscle Cell Differentiation
RNA Processing
Pathways
Drugs
Diseases
GWAS
Plasma free amino acid levels (adjusted for twenty other PFAAs) (
30659259
)
Platelet count (
29403010
)
Serum metabolite levels (
23093944
)
Interacting Genes
75 interacting genes:
ADARB1
AIMP1
AIMP2
APOBEC3B
AQR
C1QBP
DARS1
DDX1
DDX21
DDX3X
DHX36
EDC4
EIF2AK2
EPRS1
ESRP1
FAM98A
FAM98B
FUS
G3BP2
HNRNPA0
HNRNPA1
HNRNPA2B1
HNRNPA3
HNRNPF
HNRNPH1
HNRNPH2
HNRNPH3
HNRNPK
HNRNPL
HNRNPM
HNRNPR
IGF2BP1
IGF2BP2
IGF2BP3
KNOP1
LARP7
LIN28A
LRPPRC
MATR3
MSI2
NONO
PDCD11
PLOD1
PRMT1
PTBP1
PTBP3
PUF60
PURA
QARS1
RBFOX2
RBM14
RBM4
RBMS2
RTCA
RTCB
SF3B1
SF3B2
SF3B3
SF3B4
SFPQ
SPOUT1
SUGP2
SYNCRIP
TAF15
TENT2
TRA2A
TRA2B
U2SURP
UPF1
UTP20
YBX1
YBX2
YBX3
ZFR
ZNF346
22 interacting genes:
DIPK1B
FOXP1
MIR1-2
MIR155
MIR15B
MIR16-2
MIR19A
MIR19B1
MIR19B2
MIR205
MIR222
MIR29A
MIR29B1
MIR34C
MIR7-1
MIR7-2
MIR9-2
MIR92A2
MIR93
MIRLET7C
SRPK1
UBC
Entrez ID
407007
5939
HPRD ID
03860
Ensembl ID
ENSG00000207725
ENSG00000076067
Uniprot IDs
Q15434
PDB IDs
1X4E
Enriched GO Terms of Interacting Partners
?
RNA Binding
Nucleic Acid Binding
RNA Processing
RNA Splicing
RNA Metabolic Process
MRNA Processing
MRNA Metabolic Process
Nucleic Acid Metabolic Process
Nucleobase-containing Compound Metabolic Process
MRNA Binding
Regulation Of RNA Splicing
Regulation Of MRNA Metabolic Process
Nucleus
MRNA Splicing, Via Spliceosome
RNA Splicing, Via Transesterification Reactions
Macromolecule Metabolic Process
Ribonucleoprotein Complex
Post-transcriptional Regulation Of Gene Expression
Spliceosomal Complex
Catalytic Step 2 Spliceosome
Nucleoplasm
Negative Regulation Of MRNA Metabolic Process
Regulation Of MRNA Processing
Regulation Of Translation
Regulation Of MRNA Splicing, Via Spliceosome
Negative Regulation Of RNA Catabolic Process
MRNA 3'-UTR Binding
MiRNA Binding
Regulation Of Gene Expression
Cytoplasmic Stress Granule
Regulation Of Macromolecule Biosynthetic Process
Regulation Of Macromolecule Metabolic Process
Negative Regulation Of Translation
Negative Regulation Of MRNA Catabolic Process
RNA Stabilization
Positive Regulation Of Gene Expression
Regulation Of Primary Metabolic Process
MRNA Stabilization
Regulation Of Metabolic Process
Negative Regulation Of Macromolecule Metabolic Process
Positive Regulation Of Cytoplasmic Translation
Negative Regulation Of Metabolic Process
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Aminoacyl-tRNA Synthetase Multienzyme Complex
CRD-mediated MRNA Stabilization
Regulation Of Alternative MRNA Splicing, Via Spliceosome
MRNA 5'-UTR Binding
Regulation Of MRNA Stability
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Translation
MiRNA-mediated Post-transcriptional Gene Silencing
RISC Complex
Regulatory NcRNA-mediated Post-transcriptional Gene Silencing
Post-transcriptional Gene Silencing
Regulatory NcRNA-mediated Gene Silencing
Post-transcriptional Regulation Of Gene Expression
MRNA Base-pairing Post-transcriptional Repressor Activity
Negative Regulation Of Gene Expression
Negative Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Biosynthetic Process
Extracellular Vesicle
Negative Regulation Of Macromolecule Metabolic Process
Negative Regulation Of Metabolic Process
MRNA 3'-UTR Binding
Negative Regulation Of Cytokine Production
Regulation Of Gene Expression
Regulation Of Macromolecule Biosynthetic Process
MiRNA-mediated Gene Silencing By MRNA Destabilization
Negative Regulation Of Multicellular Organismal Process
MiRNA-mediated Gene Silencing By Inhibition Of Translation
Regulation Of Macromolecule Metabolic Process
Negative Regulation Of Angiogenesis
Negative Regulation Of Vasculature Development
Regulation Of Cytokine Production
Negative Regulation Of Matrix Metallopeptidase Secretion
Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Regulation Of Metabolic Process
Negative Regulation Of Developmental Process
Negative Regulation Of Cell Migration
MRNA Destabilization
RNA Destabilization
Negative Regulation Of Cell Motility
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Negative Regulation Of Cellular Response To Transforming Growth Factor Beta Stimulus
Negative Regulation Of Extracellular Matrix Assembly
Negative Regulation Of Locomotion
Positive Regulation Of MRNA Catabolic Process
Regulation Of Matrix Metallopeptidase Secretion
Negative Regulation Of Signal Transduction
Extracellular Space
Negative Regulation Of Cell Communication
Negative Regulation Of Signaling
Negative Regulation Of Vascular Endothelial Growth Factor Production
Positive Regulation Of MRNA Metabolic Process
Negative Regulation Of Cell Differentiation
Regulation Of Muscle Cell Differentiation
Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Regulation Of Heart Growth
Regulation Of Cell Migration
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Tagcloud (Intersection)
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