RIC3 and FATE1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		RIC3	FATE1
Description		RIC3 acetylcholine receptor chaperone	fetal and adult testis expressed 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Membrane Neuron Projection Neuronal Cell Body Intracellular Membrane-bounded Organelle Synapse	Cytoplasm Mitochondrion Mitochondrial Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Mitochondria-associated Endoplasmic Reticulum Membrane Contact Site
	Molecular Function	Protein Binding Acetylcholine Receptor Binding Protein Folding Chaperone	Protein Binding Ubiquitin Protein Ligase Binding Identical Protein Binding
	Biological Process	Protein Folding Positive Regulation Of Cytosolic Calcium Ion Concentration Synaptic Transmission, Cholinergic Protein Localization To Cell Surface Protein-containing Complex Assembly Positive Regulation Of Protein Localization To Cell Surface	Apoptotic Process Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Mitochondrial Calcium Ion Concentration
Pathways
Drugs		Theophylline
Diseases
GWAS		Blood protein levels ( 30072576) Body mass index ( 26426971) Body mass index (age <50) ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Malaria ( 31844061)	Systemising ( 31508503)
Interacting Genes		16 interacting genes: BCL2L1 CACNA1C CLN6 FA2H FATE1 GOSR2 NINJ2 PRB1 STX12 STX7 TMBIM1 TMEFF2 TMEM11 TMEM86A TRAF3IP3 YIF1A	99 interacting genes: AGTRAP APOL3 AQP9 ASGR2 ATCAY BCL2L2 BIK BNIP2 BNIP3 BNIP3L BSND BTN2A2 C1QL4 CALN1 CCDC70 CD302 CD79A CD83 CDC37 CERS4 CREB3L3 CSF2RA CTRL CXCR1 CXCR3 DCTN5 DNAJC30 EMD FAM177A1 FAM209A FRMD8 GIMAP5 GINM1 GOSR2 GPR25 HSD17B13 INPP5K KASH5 KCNS2 LMNA LNPEP LRRC25 MARCHF2 MARCHF3 MARCHF5 MARVELD2 MFF MOSPD3 MR1 NDUFB11 NRG4 NRSN1 OCLN OTOP2 PIN4 PKMYT1 PLP2 PRRG2 RBFA RIC3 RNF183 RPRM RTP2 SCAMP5 SEC22A SEC22C SEC23A SEC23B SLC38A1 SLC41A2 SLC7A1 SLC7A14 SMIM14 SNAP47 SSMEM1 SYNDIG1 SYNE4 SYNGR1 SYNGR2 SYNPR TBP TIMMDC1 TM4SF4 TMEM11 TMEM179B TMEM201 TMEM74 TRAF2 TRAF3IP3 UBE2I UNC93B1 USHBP1 USP20 VSIG4 VSTM1 YIPF2 YIPF4 ZCCHC12 ZFPL1
Entrez ID		79608	89885
HPRD ID		17974	02346
Ensembl ID		ENSG00000166405	ENSG00000147378
Uniprot IDs		A0A0S2Z607 A0A0S2Z6D3 B7Z3Z0 Q7Z5B4	Q969F0
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane SNARE Complex SNAP Receptor Activity Membrane Organization Endoplasmic Reticulum SNARE Binding Vesicle Fusion Organelle Membrane Fusion Regulation Of Protein Localization To Plasma Membrane Organelle Fusion Golgi Membrane Endoplasmic Reticulum Membrane Regulation Of Protein Localization To Cell Periphery Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Negative Regulation Of Protein Localization To Plasma Membrane Membrane Fusion Regulation Of Protein Localization To Membrane Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Apoptotic Process In Bone Marrow Cell Mitochondrial Outer Membrane Negative Regulation Of Integrin Biosynthetic Process 4-hydroxysphinganine Ceramide Fatty Acyl 2-hydroxylase Activity Free Fatty Acid 2-hydroxylase Activity Fatty Acid 2-hydroxylase Activity Glycosphingolipid Metabolic Process Calcium Ion Transmembrane Transport Via High Voltage-gated Calcium Channel Endomembrane System Vesicle Docking Negative Regulation Of Fas Signaling Pathway Sebaceous Gland Cell Differentiation Glucosylceramide Biosynthetic Process Regulation Of Sebum Secreting Cell Proliferation Regulation Of Acinar Cell Proliferation Alkenylglycerophosphocholine Hydrolase Activity Dendritic Cell Proliferation Dendritic Cell Apoptotic Process Membrane Depolarization During Atrial Cardiac Muscle Cell Action Potential Calcium Channel Activity Voltage-gated Calcium Channel Activity Involved In AV Node Cell Action Potential Voltage-gated Calcium Channel Activity Involved In Cardiac Muscle Cell Action Potential Vesicle Organization Tertiary Granule Organelle Localization By Membrane Tethering Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Central Nervous System Myelin Maintenance Membrane Docking Vesicle-mediated Transport Membrane Destabilizing Activity Positive Regulation Of Receptor Localization To Synapse Glycolipid Metabolic Process	Membrane Protein Binding Endoplasmic Reticulum Nuclear Envelope Membrane Organization Endoplasmic Reticulum Membrane Cytoplasmic Vesicle Spindle Pole Centrosome Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Synaptic Vesicle Membrane Organization Vesicle-mediated Transport Perinuclear Region Of Cytoplasm Positive Regulation Of Mitochondrial Fission COPII-coated Vesicle Budding
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