SNX10 and ARL6IP1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SNX10	ARL6IP1
Description		sorting nexin 10	ARL6 interacting reticulophagy regulator 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Endosome Endoplasmic Reticulum Centrosome Cytoskeleton Endosome Membrane Membrane Secretory Granule Extrinsic Component Of Endosome Membrane Apical Cytoplasm	Cytoplasm Endoplasmic Reticulum Sec61 Translocon Complex Endoplasmic Reticulum Membrane Cytosol Endomembrane System Membrane Endoplasmic Reticulum Tubular Network
	Molecular Function	Protein Binding 1-phosphatidylinositol Binding Lipid Binding Phosphatidylinositol Binding ATPase Binding Phosphatidylinositol Phosphate Binding	Protein Binding Identical Protein Binding
	Biological Process	Gastric Acid Secretion Intracellular Protein Transport Endocytosis Endosome Organization Protein Transport Vesicle Organization Cellular Homeostasis Cell Projection Organization Osteoclast Differentiation Bone Mineralization Involved In Bone Maturation Tooth Eruption Bone Resorption Bone Remodeling Establishment Of Localization In Cell Calcium Ion Homeostasis Cilium Assembly Protein Localization To Cilium Protein Localization To Centrosome Ruffle Assembly Cellular Response To Leukemia Inhibitory Factor	Positive Regulation Of L-glutamate Import Across Plasma Membrane Cotranslational Protein Targeting To Membrane Apoptotic Process Negative Regulation Of Apoptotic Process Endoplasmic Reticulum Tubular Network Formation Regulation Of Endoplasmic Reticulum Tubular Network Organization Endoplasmic Reticulum Tubular Network Membrane Organization
Pathways
Drugs
Diseases
GWAS		A body shape index ( 34021172) Dental caries (decayed, missing and filled teeth) ( 31533690) HDL cholesterol ( 30275531) HDL cholesterol levels ( 32203549) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Mean reticulocyte volume ( 32888494) Metabolic syndrome ( 31589552) Metabolite levels ( 23823483) Triglyceride levels ( 32203549) Vaginal microbiome composition (G. vaginalis) ( 32723796) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 26426971 34021172) Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971) Waist-to-hip ratio adjusted for body mass index ( 25673412)	Caffeine consumption from coffee or tea ( 33287642) Refractive error ( 32231278)
Interacting Genes		3 interacting genes: ARL6IP1 RABAC1 YIF1A	78 interacting genes: ACSF2 AQP6 ARL4D ARL6 BCL2L13 C19orf18 CERT1 DIABLO DRC4 EHD3 EMP1 F2RL1 FBXW7 FDFT1 FXR2 GAD2 GOLPH3 GOLPH3L GORASP2 GPR151 GPR152 HGS HMGCL HSD17B13 INPP5K LMNA MCEMP1 MGST3 MIEF2 MTERF3 MYG1 NAPB NDRG4 NTAQ1 NUDT3 PAM16 PBX3 PICK1 PTPN9 RAB33A REEP6 RETREG3 RNF5 SDCBP SENP2 SHISA5 SHMT2 SLC10A6 SLC13A1 SLC35H1 SLC61A1 SLC71A2 SNX1 SNX10 SNX11 SNX12 SNX15 SNX2 SNX3 SNX4 SNX8 SPG21 STARD4 SUCLA2 TARS2 TFAM TMED8 TMEM14B TMEM248 TMEM258 TUFM UBE2I VMA21 WDFY2 WIPI2 YIPF4 ZFYVE21 ZNF391
Entrez ID		29887	23204
HPRD ID		15409	09641
Ensembl ID		ENSG00000086300	ENSG00000170540
Uniprot IDs		B4DJM0 G5E9H5 Q8N5Z3 Q9Y5X0	Q15041
PDB IDs		4ON3 4PZG 6KOK
Enriched GO Terms of Interacting Partners?		Sec61 Translocon Complex Endoplasmic Reticulum Tubular Network Membrane Organization Positive Regulation Of L-glutamate Import Across Plasma Membrane Regulation Of Endoplasmic Reticulum Tubular Network Organization Regulation Of L-glutamate Import Across Plasma Membrane Endoplasmic Reticulum Tubular Network Formation Proline-rich Region Binding Endoplasmic Reticulum Tubular Network Endoplasmic Reticulum Membrane Organization Endoplasmic Reticulum Tubular Network Organization Positive Regulation Of Amino Acid Transport Cotranslational Protein Targeting To Membrane GTPase Binding COPII-coated ER To Golgi Transport Vesicle Endoplasmic Reticulum Membrane Endoplasmic Reticulum Organization Endoplasmic Reticulum-Golgi Intermediate Compartment Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Protein Targeting To Membrane Regulation Of Amine Transport	Lipid Binding Phosphatidylinositol Binding Cellular Localization Establishment Of Protein Localization Retromer Complex Intracellular Transport Protein Transport Membrane Establishment Of Localization In Cell Leptin Receptor Binding Localization Within Membrane Intracellular Protein Transport Early Endosome To Golgi Transport Intracellular Protein Localization Vesicle-mediated Transport To The Plasma Membrane Golgi Vesicle Transport Retrograde Transport, Endosome To Golgi Endosome Phosphatidylinositol-4-phosphate Binding Transferrin Receptor Binding Negative Regulation Of Early Endosome To Late Endosome Transport Endosomal Transport Endocytic Recycling Cytosolic Transport Early Endosome Membrane Phosphatidylinositol-3-phosphate Binding Protein Targeting To Golgi Apparatus Protein Binding Mitochondrial Matrix Early Endosome Retromer, Tubulation Complex Golgi Vesicle Budding Cargo Adaptor Activity Establishment Of Protein Localization To Plasma Membrane Insulin Receptor Binding Vesicle-mediated Transport Organelle Organization Phosphatidylinositol Phosphate Binding Late Endosome To Golgi Transport Succinate Metabolic Process Lamellipodium Morphogenesis Epidermal Growth Factor Receptor Binding Vesicle Budding From Membrane Protein Localization To Membrane Vesicle Organization Positive Regulation Of Exocytosis Regulation Of Establishment Of Protein Localization Membrane Organization Golgi Cisterna Regulation Of Protein Localization
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