SNX10

Description		sorting nexin 10
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GO Annotations	Cellular Component	Nucleus Cytoplasm Endosome Endoplasmic Reticulum Centrosome Cytoskeleton Endosome Membrane Membrane Secretory Granule Extrinsic Component Of Endosome Membrane Apical Cytoplasm
	Molecular Function	Protein Binding 1-phosphatidylinositol Binding Lipid Binding Phosphatidylinositol Binding ATPase Binding Phosphatidylinositol Phosphate Binding
	Biological Process	Gastric Acid Secretion Intracellular Protein Transport Endocytosis Endosome Organization Protein Transport Vesicle Organization Cellular Homeostasis Cell Projection Organization Osteoclast Differentiation Bone Mineralization Involved In Bone Maturation Tooth Eruption Bone Resorption Bone Remodeling Establishment Of Localization In Cell Calcium Ion Homeostasis Cilium Assembly Protein Localization To Cilium Protein Localization To Centrosome Ruffle Assembly Cellular Response To Leukemia Inhibitory Factor
Pathways
Drugs
Diseases
GWAS		A body shape index ( 34021172) Dental caries (decayed, missing and filled teeth) ( 31533690) HDL cholesterol ( 30275531) HDL cholesterol levels ( 32203549) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Mean reticulocyte volume ( 32888494) Metabolic syndrome ( 31589552) Metabolite levels ( 23823483) Triglyceride levels ( 32203549) Vaginal microbiome composition (G. vaginalis) ( 32723796) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 26426971 34021172) Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971) Waist-to-hip ratio adjusted for body mass index ( 25673412)
Interacting Genes		3 interacting genes: ARL6IP1 RABAC1 YIF1A
Entrez ID		29887
HPRD ID		15409
Ensembl ID		ENSG00000086300
Uniprot IDs		B4DJM0 G5E9H5 Q8N5Z3 Q9Y5X0
PDB IDs		4ON3 4PZG 6KOK
Enriched GO Terms of Interacting Partners?		Sec61 Translocon Complex Endoplasmic Reticulum Tubular Network Membrane Organization Positive Regulation Of L-glutamate Import Across Plasma Membrane Regulation Of Endoplasmic Reticulum Tubular Network Organization Regulation Of L-glutamate Import Across Plasma Membrane Endoplasmic Reticulum Tubular Network Formation Proline-rich Region Binding Endoplasmic Reticulum Tubular Network Endoplasmic Reticulum Membrane Organization Endoplasmic Reticulum Tubular Network Organization Positive Regulation Of Amino Acid Transport Cotranslational Protein Targeting To Membrane GTPase Binding COPII-coated ER To Golgi Transport Vesicle Endoplasmic Reticulum Membrane Endoplasmic Reticulum Organization Endoplasmic Reticulum-Golgi Intermediate Compartment Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Protein Targeting To Membrane Regulation Of Amine Transport
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