VAMP5 and SNAP23

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		VAMP5	SNAP23
Gene Name		vesicle-associated membrane protein 5	synaptosomal-associated protein, 23kDa
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Late Endosome Trans-Golgi Network Plasma Membrane Integral Component Of Plasma Membrane Synaptic Vesicle Cell Surface Intercalated Disc Cytoplasmic Vesicle Membrane SNARE Complex Integral Component Of Organelle Membrane Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome	Nucleoplasm Cytoplasm Plasma Membrane Focal Adhesion SNARE Complex Specific Granule Azurophil Granule Mast Cell Granule Neuron Projection Synapse Extracellular Vesicular Exosome
	Molecular Function	SNARE Binding SNAP Receptor Activity	SNAP Receptor Activity Protein Binding Syntaxin Binding
	Biological Process	Exocytosis Vesicle Fusion Neurotransmitter Secretion Muscle Organ Development Skeletal Muscle Tissue Development Cell Differentiation Golgi To Plasma Membrane Protein Transport	Histamine Secretion By Mast Cell Post-Golgi Vesicle-mediated Transport Vesicle Targeting Protein Transport Synaptic Vesicle Priming Synaptic Vesicle Fusion To Presynaptic Membrane Membrane Organization Membrane Fusion
Pathways			Translocation of GLUT4 to the plasma membrane trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding
Drugs
Diseases
GWAS		Prostate cancer ( 21743467)
Protein-Protein Interactions		6 interactors: MDC1 SNAP23 SNAP29 STX16 STX1A STX4	34 interactors: ABI2 ABI3 CFTR FXR2 ITSN1 KIF5B MATR3 NAPA NAPB PRKCA SCAMP1 SCAMP2 SCGN SNAPIN SNTG1 STX11 STX12 STX1A STX1B STX2 STX3 STX4 STX5 STX6 STXBP2 STXBP5 TLK1 VAMP1 VAMP2 VAMP3 VAMP5 VAMP7 VAMP8 WASH2P
Entrez ID		10791	8773
HPRD ID		09513	03962
Ensembl ID		ENSG00000168899	ENSG00000092531
Uniprot IDs		O95183 Q6FG93	A8K287 O00161
PDB IDs			1NHL 3ZUS
Enriched GO Terms of Interacting Partners?		Vesicle Fusion Synaptic Vesicle Fusion To Presynaptic Membrane Organelle Fusion Membrane Fusion Vesicle Organization Synaptic Vesicle Exocytosis Neurotransmitter Secretion Synaptic Vesicle Transport Regulation Of Neurotransmitter Levels Neurotransmitter Transport Establishment Of Vesicle Localization Vesicle Localization Membrane Organization Establishment Of Organelle Localization Exocytosis Vesicle Docking Membrane Docking Organelle Localization Synaptic Vesicle Priming Secretion By Cell Protein Transport Vesicle-mediated Transport Establishment Of Protein Localization Synaptic Transmission Secretion Protein Localization Establishment Of Localization In Cell Golgi Vesicle Transport Cell-cell Signaling Vesicle Targeting Cellular Protein Complex Assembly Cellular Localization Positive Regulation Of Exocytosis Post-Golgi Vesicle-mediated Transport Organelle Organization Intracellular Transport Positive Regulation Of Synaptic Transmission Cellular Macromolecular Complex Assembly Positive Regulation Of Eosinophil Degranulation Regulation Of Exocytosis Intracellular Protein Transport Regulation Of Insulin Secretion Regulation Of Peptide Hormone Secretion Protein Complex Assembly Golgi Ribbon Formation Regulation Of Hormone Secretion Positive Regulation Of Protein Localization To Cell Surface Transport Autophagic Vacuole Fusion Positive Regulation Of Immunoglobulin Secretion See more	Vesicle Fusion Membrane Fusion Organelle Fusion Vesicle Organization Vesicle-mediated Transport Establishment Of Localization In Cell Exocytosis Cellular Localization Protein Transport Membrane Organization Establishment Of Protein Localization Intracellular Transport Secretion By Cell Synaptic Vesicle Fusion To Presynaptic Membrane Vesicle Docking Membrane Docking Secretion Protein Localization Neurotransmitter Secretion Intracellular Protein Transport Post-Golgi Vesicle-mediated Transport Regulation Of Neurotransmitter Levels Synaptic Vesicle Exocytosis Neurotransmitter Transport Synaptic Vesicle Transport Golgi Vesicle Transport Transport Establishment Of Vesicle Localization Vesicle Localization Cellular Protein Localization SNARE Complex Assembly Regulation Of Exocytosis Establishment Of Organelle Localization Organelle Organization Regulation Of Cellular Localization Cell-cell Signaling Organelle Localization Synaptic Transmission Regulation Of Secretion Regulation Of Vesicle-mediated Transport Calcium Ion-dependent Exocytosis Positive Regulation Of Synaptic Transmission Regulation Of Synaptic Vesicle Priming Positive Regulation Of Exocytosis Golgi To Plasma Membrane Protein Transport Positive Regulation Of Transport Neutrophil Degranulation Regulation Of Cellular Component Organization Golgi To Plasma Membrane Transport Regulation Of Synaptic Transmission See more
Tagcloud ?		apparatus arrangement autolysosomes caveolin compartments differentiating ends existence golgi junction myofibers myotendinous myotube myotubes near neuromuscular organelles perinuclear reticulum rough sarcolemma sarcoplasmic tubules vamp2 vamp3 vamps vesicle vesicles vesicular	apical brevin brevins cellubrevin clostridial codistributed cryosections exocytosis exocytotic immunogold insensitive maleimide nem neurotoxin neurotoxins nsf nts proteolyze snare snares syntaxin tent tetanus ti ultrathin vamp vesicle
Tagcloud (Difference) ?		apparatus arrangement autolysosomes caveolin compartments differentiating ends existence golgi junction myofibers myotendinous myotube myotubes near neuromuscular organelles perinuclear reticulum rough sarcolemma sarcoplasmic tubules vamp2 vamp3 vamps vesicles vesicular	apical brevin brevins cellubrevin clostridial codistributed cryosections exocytosis exocytotic immunogold insensitive maleimide nem neurotoxin neurotoxins nsf nts proteolyze snare snares syntaxin tent tetanus ti ultrathin vamp
Tagcloud (Intersection) ?		vesicle