VAMP5 and STX4

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		VAMP5	STX4
Gene Name		vesicle-associated membrane protein 5	syntaxin 4
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Late Endosome Trans-Golgi Network Plasma Membrane Integral Component Of Plasma Membrane Synaptic Vesicle Cell Surface Intercalated Disc Cytoplasmic Vesicle Membrane SNARE Complex Integral Component Of Organelle Membrane Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome	Extracellular Space Intracellular Endosome Vacuole Trans-Golgi Network Cytosol Plasma Membrane Synaptic Vesicle Cell Surface Membrane Integral Component Of Membrane Basolateral Plasma Membrane Lamellipodium SNARE Complex Myelin Sheath Adaxonal Region Somatodendritic Compartment Specific Granule Dendritic Spine Lateral Loop Synapse Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	SNARE Binding SNAP Receptor Activity	SNARE Binding SNAP Receptor Activity Protein Binding Sphingomyelin Phosphodiesterase Activator Activity
	Biological Process	Exocytosis Vesicle Fusion Neurotransmitter Secretion Muscle Organ Development Skeletal Muscle Tissue Development Cell Differentiation Golgi To Plasma Membrane Protein Transport	Intracellular Protein Transport Post-Golgi Vesicle-mediated Transport Blood Coagulation Positive Regulation Of Cell Proliferation Regulation Of Exocytosis Platelet Activation Positive Regulation Of Cell Migration Synaptic Vesicle Fusion To Presynaptic Membrane Response To Hydroperoxide SNARE Complex Assembly Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Positive Regulation Of Catalytic Activity Positive Regulation Of Eosinophil Degranulation Positive Regulation Of Cell Adhesion Vesicle Docking Organelle Fusion Positive Regulation Of Chemotaxis Positive Regulation Of Immunoglobulin Secretion Long-term Synaptic Potentiation Membrane Organization Positive Regulation Of Establishment Of Protein Localization To Plasma Membrane Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Positive Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of Protein Localization To Cell Surface
Pathways			Response to elevated platelet cytosolic Ca2+ Translocation of GLUT4 to the plasma membrane Disinhibition of SNARE formation Platelet activation, signaling and aggregation trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding
Drugs
Diseases
GWAS		Prostate cancer ( 21743467)
Protein-Protein Interactions		6 interactors: MDC1 SNAP23 SNAP29 STX16 STX1A STX4	48 interactors: ACTB BET1 CYBRD1 DLG1 GIMAP5 GOSR2 ITSN2 LLGL1 NAPA NAPB NSF PSMA3 RAB11A RAB4A RAB5A SCRIB SEC22A SEPT5 SNAP23 SNAP25 SNAP29 SNAP47 STX12 STX16 STX3 STX5 STX6 STX7 STX8 STXBP3 STXBP4 STXBP5 STXBP6 SYT1 SYT4 SYT7 TXLNA TXLNB TXLNG VAMP1 VAMP2 VAMP3 VAMP4 VAMP5 VAMP7 VAMP8 VAPB VTI1B
Entrez ID		10791	6810
HPRD ID		09513	01722
Ensembl ID		ENSG00000168899	ENSG00000103496
Uniprot IDs		O95183 Q6FG93	A8MXY0 B7Z425 Q12846
PDB IDs
Enriched GO Terms of Interacting Partners?		Vesicle Fusion Synaptic Vesicle Fusion To Presynaptic Membrane Organelle Fusion Membrane Fusion Vesicle Organization Synaptic Vesicle Exocytosis Neurotransmitter Secretion Synaptic Vesicle Transport Regulation Of Neurotransmitter Levels Neurotransmitter Transport Establishment Of Vesicle Localization Vesicle Localization Membrane Organization Establishment Of Organelle Localization Exocytosis Vesicle Docking Membrane Docking Organelle Localization Synaptic Vesicle Priming Secretion By Cell Protein Transport Vesicle-mediated Transport Establishment Of Protein Localization Synaptic Transmission Secretion Protein Localization Establishment Of Localization In Cell Golgi Vesicle Transport Cell-cell Signaling Vesicle Targeting Cellular Protein Complex Assembly Cellular Localization Positive Regulation Of Exocytosis Post-Golgi Vesicle-mediated Transport Organelle Organization Intracellular Transport Positive Regulation Of Synaptic Transmission Cellular Macromolecular Complex Assembly Positive Regulation Of Eosinophil Degranulation Regulation Of Exocytosis Intracellular Protein Transport Regulation Of Insulin Secretion Regulation Of Peptide Hormone Secretion Protein Complex Assembly Golgi Ribbon Formation Regulation Of Hormone Secretion Positive Regulation Of Protein Localization To Cell Surface Transport Autophagic Vacuole Fusion Positive Regulation Of Immunoglobulin Secretion	Vesicle Fusion Membrane Fusion Organelle Fusion Vesicle-mediated Transport Membrane Organization Vesicle Organization Establishment Of Localization In Cell Cellular Localization Exocytosis Secretion By Cell Secretion Transport Golgi Vesicle Transport Protein Transport Establishment Of Protein Localization Protein Localization Intracellular Transport Neurotransmitter Secretion Regulation Of Exocytosis Regulation Of Cellular Localization Vesicle Docking Regulation Of Vesicle-mediated Transport Post-Golgi Vesicle-mediated Transport Membrane Docking Regulation Of Neurotransmitter Levels Intracellular Protein Transport Neurotransmitter Transport Synaptic Vesicle Exocytosis Vesicle Fusion With Golgi Apparatus Synaptic Vesicle Transport Cellular Protein Localization Regulation Of Secretion Establishment Of Vesicle Localization Vesicle Localization Cell-cell Signaling Organelle Organization Endomembrane System Organization Cytoplasmic Transport SNARE Complex Assembly Endosomal Transport Regulation Of Protein Localization To Plasma Membrane Synaptic Vesicle Fusion To Presynaptic Membrane Organelle Localization Establishment Of Organelle Localization Synaptic Transmission Golgi To Plasma Membrane Transport Regulation Of Protein Localization ER To Golgi Vesicle-mediated Transport Golgi To Plasma Membrane Protein Transport Positive Regulation Of Exocytosis
Tagcloud ?		apparatus arrangement autolysosomes caveolin compartments differentiating ends existence golgi junction myofibers myotendinous myotube myotubes near neuromuscular organelles perinuclear reticulum rough sarcolemma sarcoplasmic tubules vamp2 vamp3 vamps vesicle vesicles vesicular	address ageing armx3 b2mg consequence dep1 ebp50 effectors fact issue lancl1 maintaining modulators note ntal organismal pld3 preferentially recognize screened senescence senescent sorting straightforward triggering utilized vamp3 view vps26a
Tagcloud (Difference) ?		apparatus arrangement autolysosomes caveolin compartments differentiating ends existence golgi junction myofibers myotendinous myotube myotubes near neuromuscular organelles perinuclear reticulum rough sarcolemma sarcoplasmic tubules vamp2 vamps vesicle vesicles vesicular	address ageing armx3 b2mg consequence dep1 ebp50 effectors fact issue lancl1 maintaining modulators note ntal organismal pld3 preferentially recognize screened senescence senescent sorting straightforward triggering utilized view vps26a
Tagcloud (Intersection) ?		vamp3