VAMP5 and STX1A

Number of citations of the paper that reports this interaction (PMID 24722188)
1

Data Source:
BioGRID (two hybrid)

		VAMP5	STX1A
Gene Name		vesicle-associated membrane protein 5	syntaxin 1A (brain)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Late Endosome Trans-Golgi Network Plasma Membrane Integral Component Of Plasma Membrane Synaptic Vesicle Cell Surface Intercalated Disc Cytoplasmic Vesicle Membrane SNARE Complex Integral Component Of Organelle Membrane Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome	Extracellular Region Cytosol Plasma Membrane Synaptic Vesicle Endomembrane System Integral Component Of Membrane Cell Junction Secretory Granule Synaptic Vesicle Membrane SNARE Complex Actomyosin Neuron Projection Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I Complex Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II Complex Synaptobrevin 2-SNAP-25-syntaxin-1a Complex
	Molecular Function	SNARE Binding SNAP Receptor Activity	SNARE Binding Glycoprotein Binding SNAP Receptor Activity Protein Binding Myosin Binding Calcium Channel Inhibitor Activity Chloride Channel Inhibitor Activity Kinase Binding Protein Domain Specific Binding Protein Binding, Bridging Myosin Head/neck Binding ATP-dependent Protein Binding Protein Heterodimerization Activity Protein N-terminus Binding Calcium-dependent Protein Binding
	Biological Process	Exocytosis Vesicle Fusion Neurotransmitter Secretion Muscle Organ Development Skeletal Muscle Tissue Development Cell Differentiation Golgi To Plasma Membrane Protein Transport	Positive Regulation Of Neurotransmitter Secretion Energy Reserve Metabolic Process Intracellular Protein Transport Synaptic Transmission Neurotransmitter Secretion Pathogenesis Response To Gravity Regulation Of Synaptic Vesicle Priming Glutamate Secretion Synaptic Vesicle Docking Calcium Ion-dependent Exocytosis Synaptic Vesicle Fusion To Presynaptic Membrane Secretion By Cell Cellular Protein Metabolic Process Small Molecule Metabolic Process Positive Regulation Of Exocytosis Vesicle Docking Regulation Of Insulin Secretion Positive Regulation Of Excitatory Postsynaptic Membrane Potential
Pathways			Dopamine Neurotransmitter Release Cycle Integration of energy metabolism Acetylcholine Neurotransmitter Release Cycle Regulation of insulin secretion Toxicity of botulinum toxin type C (BoNT/C) Norepinephrine Neurotransmitter Release Cycle GABA synthesis, release, reuptake and degradation Glutamate Neurotransmitter Release Cycle Peptide hormone metabolism Uptake and actions of bacterial toxins Neurotransmitter Release Cycle Insulin processing Serotonin Neurotransmitter Release Cycle Neurotoxicity of clostridium toxins Transmission across Chemical Synapses
Drugs
Diseases
GWAS		Prostate cancer ( 21743467)
Protein-Protein Interactions		6 interactors: MDC1 SNAP23 SNAP29 STX16 STX1A STX4	58 interactors: ABCC9 APBA1 ATP4B ATP6V1B1 CACNA1D CCSER2 CDK5 CFTR CPLX1 CSNK2A1 CSNK2A2 DAPK1 KCNB1 NAPA NAPB NSF PSMA3 RAB27A RIMS1 SCNN1A SCNN1B SCNN1G SDCBP SEPT2 SEPT5 SLC6A1 SLC6A2 SLC6A3 SLC6A4 SLC6A5 SLC6A9 SNAP23 SNAP25 SNAP29 SNPH STX8 STXBP1 STXBP2 STXBP5 STXBP6 SUMO1P1 SYT1 SYT4 SYT7 SYTL4 TRDMT1 TXLNA TXLNB UNC13B VAMP1 VAMP2 VAMP5 VAMP7 VAMP8 VAPB VIM VPS11 VPS18
Entrez ID		10791	6804
HPRD ID		09513	01721
Ensembl ID		ENSG00000168899	ENSG00000106089
Uniprot IDs		O95183 Q6FG93	A8MZ54 Q16623 Q75ME0
PDB IDs
Enriched GO Terms of Interacting Partners?		Vesicle Fusion Synaptic Vesicle Fusion To Presynaptic Membrane Organelle Fusion Membrane Fusion Vesicle Organization Synaptic Vesicle Exocytosis Neurotransmitter Secretion Synaptic Vesicle Transport Regulation Of Neurotransmitter Levels Neurotransmitter Transport Establishment Of Vesicle Localization Vesicle Localization Membrane Organization Establishment Of Organelle Localization Exocytosis Vesicle Docking Membrane Docking Organelle Localization Synaptic Vesicle Priming Secretion By Cell Protein Transport Vesicle-mediated Transport Establishment Of Protein Localization Synaptic Transmission Secretion Protein Localization Establishment Of Localization In Cell Golgi Vesicle Transport Cell-cell Signaling Vesicle Targeting Cellular Protein Complex Assembly Cellular Localization Positive Regulation Of Exocytosis Post-Golgi Vesicle-mediated Transport Organelle Organization Intracellular Transport Positive Regulation Of Synaptic Transmission Cellular Macromolecular Complex Assembly Positive Regulation Of Eosinophil Degranulation Regulation Of Exocytosis Intracellular Protein Transport Regulation Of Insulin Secretion Regulation Of Peptide Hormone Secretion Protein Complex Assembly Golgi Ribbon Formation Regulation Of Hormone Secretion Positive Regulation Of Protein Localization To Cell Surface Transport Autophagic Vacuole Fusion Positive Regulation Of Immunoglobulin Secretion	Exocytosis Secretion By Cell Neurotransmitter Transport Secretion Regulation Of Exocytosis Regulation Of Neurotransmitter Levels Transport Vesicle-mediated Transport Regulation Of Secretion Neurotransmitter Secretion Synaptic Transmission Cell-cell Signaling Regulation Of Vesicle-mediated Transport Establishment Of Localization In Cell Synaptic Vesicle Transport Synaptic Vesicle Exocytosis Cellular Localization Positive Regulation Of Exocytosis Regulation Of Cellular Localization Membrane Fusion Glutamate Secretion Establishment Of Vesicle Localization Vesicle Localization Ion Transport Vesicle Fusion Protein Transport Establishment Of Protein Localization Amino Acid Transport Vesicle Docking Organelle Fusion Membrane Docking Establishment Of Organelle Localization Membrane Organization Acid Secretion Vesicle Organization Positive Regulation Of Secretion Organelle Localization Protein Localization Monovalent Inorganic Cation Transport Anion Transport Dicarboxylic Acid Transport Regulated Secretory Pathway Metal Ion Transport Vesicle Docking Involved In Exocytosis Positive Regulation Of Transport Carboxylic Acid Transport Regulation Of Synaptic Transmission Organic Acid Transport Sodium Ion Transport Organic Anion Transport
Tagcloud ?		apparatus arrangement autolysosomes caveolin compartments differentiating ends existence golgi junction myofibers myotendinous myotube myotubes near neuromuscular organelles perinuclear reticulum rough sarcolemma sarcoplasmic tubules vamp2 vamp3 vamps vesicle vesicles vesicular	colitis colonized died h7 hemolytic hemorrhagic hus isogenic k3995 lysogenic o157 outbreak outbreaks phage phages rabbits reflects shiga spinach stec streptomycin stx2 stx2a stx2c succumbed toxin uremic virulence
Tagcloud (Difference) ?		apparatus arrangement autolysosomes caveolin compartments differentiating ends existence golgi junction myofibers myotendinous myotube myotubes near neuromuscular organelles perinuclear reticulum rough sarcolemma sarcoplasmic tubules vamp2 vamp3 vamps vesicle vesicles vesicular	colitis colonized died h7 hemolytic hemorrhagic hus isogenic k3995 lysogenic o157 outbreak outbreaks phage phages rabbits reflects shiga spinach stec streptomycin stx2 stx2a stx2c succumbed toxin uremic virulence
Tagcloud (Intersection) ?