VAMP5 and TMCO5A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		VAMP5	TMCO5A
Description		vesicle associated membrane protein 5	transmembrane and coiled-coil domains 5A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Late Endosome Golgi Apparatus Trans-Golgi Network Plasma Membrane Cell Surface Endomembrane System Intercalated Disc Membrane Cytoplasmic Vesicle Membrane Organelle Membrane Perinuclear Region Of Cytoplasm Extracellular Exosome	Nucleus Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Nuclear Membrane
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Muscle Organ Development Skeletal Muscle Tissue Development Vesicle-mediated Transport Cell Differentiation Golgi To Plasma Membrane Protein Transport
Pathways
Drugs
Diseases
GWAS		Appendicular lean mass ( 33097823) Coronary artery disease ( 26343387 29212778) Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975) Myocardial infarction ( 26343387) Platelet distribution width ( 32888494) Prostate cancer ( 21743467) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)	Body size at age 10 ( 32376654) Femoral neck bone mineral density ( 29499414) Gut microbiota (bacterial taxa) ( 27723756) Lumbar spine bone mineral density ( 29499414) Major depressive disorder ( 27479909) NASH resolution in nonalcoholic steatohepatitis ( 31832568) Total body bone mineral density ( 29304378) Urate levels in overweight individuals ( 25811787)
Interacting Genes		57 interacting genes: ABHD16A AQP6 ARL13B ASGR2 ATP6AP2 BIK CD53 CLDN5 CLDN7 COMT CPLX4 CYB5R3 ELOVL4 ERGIC3 FAM209A FNDC9 GJA8 GORAB GPR152 GPX8 GRAMD2B HIBADH HSD17B13 IL3RA JAGN1 KIR2DL3 KIR3DL3 KLRC1 LMNA LRRC25 MDC1 MUC1 NCAPH2 PANX1 PLAC8 PVR RETREG3 SAR1A SLC14A2 SLC18A1 SPINT1 STX1A STX1B STX2 TAS2R5 TM4SF18 TMCO5A TMEM106C TMEM139 TMEM14B TMEM31 TMEM45B TMEM52B TMEM86B TMPRSS2 TMX2 VSIG4	7 interacting genes: BET1 C1orf216 GOSR2 PRH1 TMEM60 TSPAN18 VAMP5
Entrez ID		10791	145942
HPRD ID		09513	11341
Ensembl ID		ENSG00000168899	ENSG00000166069
Uniprot IDs		O95183 Q6FG93	A0A024R9I9 Q8N6Q1
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Protein Binding SNARE Complex Endoplasmic Reticulum Membrane SNARE Binding Endoplasmic Reticulum Presynaptic Active Zone Membrane Synaptic Vesicle Exocytosis Monoatomic Anion Channel Activity Signal Release Norepinephrine Transport Structural Molecule Activity SNAP Receptor Activity Neurotransmitter Transport Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Vesicle Fusion To Plasma Membrane Exocytosis Regulation Of Synaptic Vesicle Priming	SNARE Complex SNAP Receptor Activity Golgi Vesicle Transport Vesicle Fusion Organelle Membrane Fusion Vesicle-mediated Transport Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Organelle Fusion Membrane Fusion Vesicle Fusion With Golgi Apparatus Endomembrane System
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