KIF1C and PTPN21

Number of citations of the paper that reports this interaction (PMID 9685376)
24

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		KIF1C	PTPN21
Gene Name		kinesin family member 1C	protein tyrosine phosphatase, non-receptor type 21
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Golgi Apparatus Kinesin Complex Microtubule	Cytoplasm Cytoskeleton
	Molecular Function	Motor Activity Protein Binding ATP Binding Microtubule Binding ATP-dependent Microtubule Motor Activity, Plus-end-directed ATPase Activity Poly(A) RNA Binding	Protein Tyrosine Phosphatase Activity Protein Binding
	Biological Process	Retrograde Vesicle-mediated Transport, Golgi To ER Microtubule-based Movement Metabolic Process Vesicle-mediated Transport Cytoskeleton-dependent Intracellular Transport	Protein Dephosphorylation Peptidyl-tyrosine Dephosphorylation
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		9 interactors: CSNK2A1 CSNK2A2 LAMC3 PTPN21 YWHAB YWHAE YWHAG YWHAQ YWHAZ	5 interactors: AKAP1 BMX KIF1C SRC TEC
Entrez ID		10749	11099
HPRD ID		04342	04468
Ensembl ID		ENSG00000129250	ENSG00000070778
Uniprot IDs		O43896	Q16825
PDB IDs		2G1L
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrion Organization Regulation Of Mitochondrion Organization Intrinsic Apoptotic Signaling Pathway Regulation Of Organelle Organization Positive Regulation Of Apoptotic Signaling Pathway Apoptotic Process Programmed Cell Death Cell Death Death Positive Regulation Of Intracellular Transport Apoptotic Signaling Pathway Positive Regulation Of Organelle Organization Protein Targeting Regulation Of Intracellular Transport Regulation Of Cellular Component Organization Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Negative Regulation Of Protein Dephosphorylation Positive Regulation Of Signal Transduction Regulation Of Establishment Of Protein Localization Nervous System Development Positive Regulation Of Transport Regulation Of Apoptotic Process Regulation Of Protein Localization Negative Regulation Of Cellular Protein Metabolic Process Regulation Of Cell Death Membrane Organization Negative Regulation Of Protein Metabolic Process Neurogenesis Intracellular Protein Transport Regulation Of Cellular Localization Negative Regulation Of Cellular Metabolic Process Hippo Signaling Cellular Protein Localization Protein Transport Mitotic Cell Cycle Process Substantia Nigra Development Establishment Of Protein Localization Cell Morphogenesis Involved In Differentiation Mitotic Spindle Checkpoint Intracellular Transport Negative Regulation Of Chromosome Segregation Mitotic Cell Cycle Generation Of Neurons System Development Spindle Checkpoint	Peptidyl-tyrosine Autophosphorylation Protein Autophosphorylation Peptidyl-tyrosine Phosphorylation Wound Healing Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Response To Wounding Integrin-mediated Signaling Pathway Response To Hydrogen Peroxide Mesoderm Development Innate Immune Response Cellular Response To Progesterone Stimulus Enzyme Linked Receptor Protein Signaling Pathway Cellular Response To Steroid Hormone Stimulus Positive Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Peptidyl-amino Acid Modification Response To Reactive Oxygen Species Intracellular Receptor Signaling Pathway Vestibular Reflex Positive Regulation Of Integrin Activation Negative Regulation Of Mitochondrial Depolarization Positive Regulation Of Podosome Assembly Negative Regulation Of Protein Homooligomerization Progesterone Receptor Signaling Pathway Fc Receptor Signaling Pathway Adaptive Immune Response Regulation Of Podosome Assembly Immune Response-activating Cell Surface Receptor Signaling Pathway Positive Regulation Of Cell Cycle Immune Response Regulation Of Caveolin-mediated Endocytosis Protein Phosphorylation Defense Response Osteoclast Development Negative Regulation Of Protein Oligomerization Response To Stress Regulation Of Cell Proliferation Movement Of Cell Or Subcellular Component Semicircular Canal Morphogenesis Regulation Of Integrin Activation Immune Response-regulating Cell Surface Receptor Signaling Pathway Regulation Of Early Endosome To Late Endosome Transport Axon Guidance Transcytosis Cellular Response To Organic Cyclic Compound Signal Complex Assembly Semicircular Canal Development Stress Fiber Assembly Cellular Response To Lipid Blood Coagulation Response To Oxidative Stress
Tagcloud ?		18b 20b 5b ancca atad2 bromodomain concerted coregulator deregulation drives impeded kif10 kif11 kif15 kif18a kif1a kif20a kif21 kif23 kif24 kif25 kif4a kif5a kif7 kifc1 kifc3 kinesin kinesins mll1	16p 17p 17q 20q 6q16 8q amplifications amplifier bbs12 bbs9 ciliogenesis dnah9 exome firestorm fmn2 foxo3 hsp90b1 idcs impc impcs micropapillary pangenomic polarity q22 sawtooth sec63 sptlc3 ubr4 unsupervised
Tagcloud (Difference) ?		18b 20b 5b ancca atad2 bromodomain concerted coregulator deregulation drives impeded kif10 kif11 kif15 kif18a kif1a kif20a kif21 kif23 kif24 kif25 kif4a kif5a kif7 kifc1 kifc3 kinesin kinesins mll1	16p 17p 17q 20q 6q16 8q amplifications amplifier bbs12 bbs9 ciliogenesis dnah9 exome firestorm fmn2 foxo3 hsp90b1 idcs impc impcs micropapillary pangenomic polarity q22 sawtooth sec63 sptlc3 ubr4 unsupervised
Tagcloud (Intersection) ?