PTPN21 and KIF1C

Number of citations of the paper that reports this interaction (PMID 9685376)
24

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		PTPN21	KIF1C
Gene Name		protein tyrosine phosphatase, non-receptor type 21	kinesin family member 1C
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytoskeleton	Endoplasmic Reticulum Golgi Apparatus Kinesin Complex Microtubule
	Molecular Function	Protein Tyrosine Phosphatase Activity Protein Binding	Motor Activity Protein Binding ATP Binding Microtubule Binding ATP-dependent Microtubule Motor Activity, Plus-end-directed ATPase Activity Poly(A) RNA Binding
	Biological Process	Protein Dephosphorylation Peptidyl-tyrosine Dephosphorylation	Retrograde Vesicle-mediated Transport, Golgi To ER Microtubule-based Movement Metabolic Process Vesicle-mediated Transport Cytoskeleton-dependent Intracellular Transport
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: AKAP1 BMX KIF1C SRC TEC	9 interactors: CSNK2A1 CSNK2A2 LAMC3 PTPN21 YWHAB YWHAE YWHAG YWHAQ YWHAZ
Entrez ID		11099	10749
HPRD ID		04468	04342
Ensembl ID		ENSG00000070778	ENSG00000129250
Uniprot IDs		Q16825	O43896
PDB IDs			2G1L
Enriched GO Terms of Interacting Partners?		Peptidyl-tyrosine Autophosphorylation Protein Autophosphorylation Peptidyl-tyrosine Phosphorylation Wound Healing Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Response To Wounding Integrin-mediated Signaling Pathway Response To Hydrogen Peroxide Mesoderm Development Innate Immune Response Cellular Response To Progesterone Stimulus Enzyme Linked Receptor Protein Signaling Pathway Cellular Response To Steroid Hormone Stimulus Positive Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Peptidyl-amino Acid Modification Response To Reactive Oxygen Species Intracellular Receptor Signaling Pathway Vestibular Reflex Positive Regulation Of Integrin Activation Negative Regulation Of Mitochondrial Depolarization Positive Regulation Of Podosome Assembly Negative Regulation Of Protein Homooligomerization Progesterone Receptor Signaling Pathway Fc Receptor Signaling Pathway Adaptive Immune Response Regulation Of Podosome Assembly Immune Response-activating Cell Surface Receptor Signaling Pathway Positive Regulation Of Cell Cycle Immune Response Regulation Of Caveolin-mediated Endocytosis Protein Phosphorylation Defense Response Osteoclast Development Negative Regulation Of Protein Oligomerization Response To Stress Regulation Of Cell Proliferation Movement Of Cell Or Subcellular Component Semicircular Canal Morphogenesis Regulation Of Integrin Activation Immune Response-regulating Cell Surface Receptor Signaling Pathway Regulation Of Early Endosome To Late Endosome Transport Axon Guidance Transcytosis Cellular Response To Organic Cyclic Compound Signal Complex Assembly Semicircular Canal Development Stress Fiber Assembly Cellular Response To Lipid Blood Coagulation Response To Oxidative Stress	Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrion Organization Regulation Of Mitochondrion Organization Intrinsic Apoptotic Signaling Pathway Regulation Of Organelle Organization Positive Regulation Of Apoptotic Signaling Pathway Apoptotic Process Programmed Cell Death Cell Death Death Positive Regulation Of Intracellular Transport Apoptotic Signaling Pathway Positive Regulation Of Organelle Organization Protein Targeting Regulation Of Intracellular Transport Regulation Of Cellular Component Organization Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Negative Regulation Of Protein Dephosphorylation Positive Regulation Of Signal Transduction Regulation Of Establishment Of Protein Localization Nervous System Development Positive Regulation Of Transport Regulation Of Apoptotic Process Regulation Of Protein Localization Negative Regulation Of Cellular Protein Metabolic Process Regulation Of Cell Death Membrane Organization Negative Regulation Of Protein Metabolic Process Neurogenesis Intracellular Protein Transport Regulation Of Cellular Localization Negative Regulation Of Cellular Metabolic Process Hippo Signaling Cellular Protein Localization Protein Transport Mitotic Cell Cycle Process Substantia Nigra Development Establishment Of Protein Localization Cell Morphogenesis Involved In Differentiation Mitotic Spindle Checkpoint Intracellular Transport Negative Regulation Of Chromosome Segregation Mitotic Cell Cycle Generation Of Neurons System Development Spindle Checkpoint
Tagcloud ?		16p 17p 17q 20q 6q16 8q amplifications amplifier bbs12 bbs9 ciliogenesis dnah9 exome firestorm fmn2 foxo3 hsp90b1 idcs impc impcs micropapillary pangenomic polarity q22 sawtooth sec63 sptlc3 ubr4 unsupervised	18b 20b 5b ancca atad2 bromodomain concerted coregulator deregulation drives impeded kif10 kif11 kif15 kif18a kif1a kif20a kif21 kif23 kif24 kif25 kif4a kif5a kif7 kifc1 kifc3 kinesin kinesins mll1
Tagcloud (Difference) ?		16p 17p 17q 20q 6q16 8q amplifications amplifier bbs12 bbs9 ciliogenesis dnah9 exome firestorm fmn2 foxo3 hsp90b1 idcs impc impcs micropapillary pangenomic polarity q22 sawtooth sec63 sptlc3 ubr4 unsupervised	18b 20b 5b ancca atad2 bromodomain concerted coregulator deregulation drives impeded kif10 kif11 kif15 kif18a kif1a kif20a kif21 kif23 kif24 kif25 kif4a kif5a kif7 kifc1 kifc3 kinesin kinesins mll1
Tagcloud (Intersection) ?